Metabolic assessment of tissue oxygenation

Seminars in Respiratory and Critical Care Medicine

Volumn 20, Issue 1, 1999, Pages 11-15

  Gutierrez, Guillermo ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Hypoxia; Metabolism; Oxygen transport

Indexed keywords

ADENYLATE KINASE; CREATINE KINASE; LACTIC ACID; VASOACTIVE AGENT;

ANAEROBIC GLYCOLYSIS; ARTERY CATHETERIZATION; CELL HYPOXIA; ENZYME MECHANISM; HUMAN; HYPOXEMIA; LACTATE BLOOD LEVEL; MORTALITY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXYGEN CONSUMPTION; OXYGEN TRANSPORT; PATHOGENESIS; PATIENT MONITORING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PULMONARY ARTERY; REVIEW; RISK ASSESSMENT; TISSUE BLOOD FLOW; TISSUE DISTRIBUTION; TISSUE METABOLISM; TISSUE OXYGENATION; TISSUE PERFUSION; TONOMETRY;

EID: 0033018318     PISSN: 10693424     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-1009442     Document Type: Review

References (37)

1. Connors AF Jr, Speroff T, Dawson NV, et al. The effectiveness of right heart catheterization in the initial care of critically ill patients. JAMA 1996;276:889-897
2. Schlichtig R, Pinsky MR. Defining the hypoxic threshold. Crit Care Med 1991;19:147-149
3. Cain SM, Curtis SE. Systemic and regional oxygen uptake and lactate flux in endotoxic dogs resuscitated with dextran and dopexamine or dextran alone. Circulatory Shock 1992;38:173-181
4. Hochachka PW. Defense strategies against hypoxia and hypothermia. Science, 1986;231:234-241
5. Hochachka PW, Mommsen TP. Protons and anaerobiosis. Science 1983;219:1391-1397
6. Gevers W. Generation of protons by metabolic processes in heart cells. J Mol Cell Cardiol 1977;9:867-874
7. Poole RC, Halestrap AP. Transport of lactate and other monocarboxylates across mammalian plasma membranes. Am J Physiol 1993;264:C761-C782
8. Roth DA, Brooks GA. Lactate and pyruvate transport is dominated by a pH gradient-sensitive carrier in rat skeletal muscle sarcolemmal vesicles. Arch Biochem Biophys 1990;279: 386-394
9. 2 deficit in hypoxic dogs. J Appl Physiol 1977;42:44-49
10. Gladden LB, Yates JW. Lactic acid infusion in dogs: effects of varying infusate pH. J Appl Physiol 1983;54:1254-1260
11. Chin ER, Lindinger MI, Heigenhauser GJF. Lactate metabolism in inactive skeletal muscle during lactacidosis. Am J Physiol 1991;261:R98-R105
12. Poortmans JR, Bossche JD, Leclercq R. Lactate uptake by inactive forearm during progressive leg exercise. J Appl Physiol 1978;45:835-839
13. Catcheside PG, Scroop GC. Lactate kinetics in resting and exercising forearms during moderate-intensity supine leg exercise. J Appl Physiol 1993;74:435-443
14. Gladden LB. Net lactate uptake during progressive steady-level contractions in canine skeletal muscle. J Appl Physiol 1991;71:514-520
15. Gutierrez G, Hurtado FJ, Gutierrez AM, Fernandez E. Net uptake of lactate by rabbit hindlimb during hypoxia. Am Rev Respir Dis 1993;148:1204-1209
16. Druml W, Grimm G, Laggner AN, Lenz K, Schneeweiß B. Lactic acid kinetics in respiratory alkalosis. Crit Care Med 1991;19:1120-1124
17. 2 in a working red muscle in situ. J Appl Physiol 1986;61:402-408
18. Rashkin MC, Bosken C, Baughman RP. Oxygen delivery in critically ill patients. Relationship to blood lactate and survival. Chest 1985;87:580-584
19. Astiz ME, Rackow EC, Kaufman B, et al. Relationship of oxygen delivery and mixed venous oxygenation to lactic acidosis in patients with sepsis and acute myocardial infarction. Crit Care Med 1988;16:655-658
20. Graf H, Leach W, Arieff AI. Evidence for a detrimental effect of bicarbonate therapy in lactic acidosis. Science 1985;227: 754-756
21. Benjamin E, Oropello JM, Abalos AM, Hannon EM, Wang JK, Fischer E, Iberti TJ. Effects of acid-base correction on hemodynamks, oxygen dynamics, and resuscitability in severe canine hemorrhagic shock. Crit Care Med 1994;22: 1616-1623
22. Stacpoole PW, Wright EC, Baumgartner TG, et al. A controlled clinical trial of dichloroacetate for treatment of lactir acidosis in adults. The Dichloroacetate-Lactic Acidosis Study Group. N Engl J Med 1992;327:1564-1569
23. Berne RM. Adenosine: An important physiological regulation. News Physiol Sci 1986;1:163-167
24. Van Belle H, Goossens F, Wynants J. Formation and release of purine catabolites during hypoperfusion, anoxia, and ischemia. Am J Physiol 1987;252:H886-H893
25. Gutierrez G, Lund N, Bryan-Brown CW. Cellular oxygen utilization during multiple organ failure. Crit Care Clin 1989; 5:271-287
26. Dudley GA, Terjung RL: Influence of acidosis on AMP deaminase activity in contracting fast-twitch muscle. Am J Physiol 1985;248:C43-C50
27. Araki R, Tamura M, Yamazaki I. The effect of intracellular oxygen concentration on lactate release, pyridine nucleotide reduction, and respiration rate in the rat cardiac tissue. Circ Res 1983;53:448-455
28. Dudley GA, Terjung RL. Influence of aerobic metabolism on IMP accumulation in fast-twitch muscle. Am J Physiol 1985; 248:C37-C42
29. Meyer RA, Dudley GA, Terjung RL. Ammonia and IMP in different skeletal muscle fibers after exercise in rats. J Appl Physiol 1980;49:1037-1041
30. Granger DN, Hollwarth MA, Parks DA. Ischemia reperfusion injury: Role of oxygen derived free radicals. Acta Physiol Scand 1986;126:4(suppl):47-63
31. Granger DN. Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury. Am J Physiol 1988;255:H1269-H1275
32. Grum CM, Simon RH, Dantzker DR, Fox IH. Evidence for adenosine triphosphate degradation in critically ill patients. Chest 1985;88:763-767
33. Bessman SP. The creatine-creatine phosphate energy shuttle. Ann Rev Biochem 1985;54:831-862
34. Gutierrez G. Cellular energy metabolism during hypoxia. Crit Care Med 1991;19:619
35. Clark CH, Gutierrez G. Gastric intramucosal pH: A noninvasive method for the indirect measurement of tissue oxygenation. Am J Crit Care 1992;1:53-60
36. Grum CM, Fiddian-Green RG, Pittenger GL, et al. Adequacy of tissue oxygenation in intact dog intestine. J Appl Physiol 1984;56:1065-1069
37. 2 metabolism. Semin Respir Crit Care Med; in press