Prediction of membrane permeability to peptides from calculated dynamic molecular surface properties

Pharmaceutical Research

Volumn 16, Issue 2, 1999, Pages 205-212

  Stenberg, Patric ^a   Luthman, Kristina ^b   Artursson, Per ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UNIVERSITY OF TROMSØ   (Norway)

Author keywords

Caco 2 cells; Hydrogen bonding; Intestinal drug transport; Lipophilicity; Molecular surface area

Indexed keywords

OLIGOPEPTIDE;

ARTICLE; CELL CULTURE; CELL STRAIN CACO 2; DRUG UPTAKE; HUMAN; HUMAN CELL; HYDROGEN BOND; HYDROPHOBICITY; MEMBRANE MODEL; MEMBRANE PERMEABILITY; MOLECULAR DYNAMICS; PARTITION COEFFICIENT; PRIORITY JOURNAL;

EID: 0033014577     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018816122458     Document Type: Article

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