Progression of Alzheimer-related neuritic plaque pathology in the entorhinal region, perirhinal cortex and hippocampal formation

Dementia and Geriatric Cognitive Disorders

Volumn 10, Issue 2, 1999, Pages 70-76

  Yilmazer Hanke, Deniz M ^a   Hanke, Joachim ^b  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b NONE

Author keywords

Alzheimer's disease; Braak's staging; Predilection sites; Sequence of neuritic plaques

Indexed keywords

AMYLOID BETA PROTEIN;

ALZHEIMER DISEASE; ARTICLE; BRAIN CORTEX; ENTORHINAL CORTEX; FEMALE; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; NEURITE; NEUROFIBRILLARY TANGLE; PRIORITY JOURNAL; SENILE PLAQUE;

AGED; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; DISEASE PROGRESSION; ENTORHINAL CORTEX; FEMALE; HIPPOCAMPUS; HUMANS; MALE; NEUROFIBRILLARY TANGLES; NEUROPIL; SENILE PLAQUES;

EID: 0033014539     PISSN: 14208008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000017104     Document Type: Article

References (45)

1. Delacourte A, Defossez A: Alzheimer's disease: Tau proteins, the promoting factors of microtubule assembly, are major components of paired helical filaments. J Neurol Sci 1986;76:173-186.
2. Grundke-Iqbal I, Iqbal K, Tung Y-C, Quinlan M, Wisniewski HM, Binder LI: Abnormal phosphorylation of the microtubule-associated protein τ (tau) in Alzheimer cytoskeletal pathology. Proc Natl Acad Sci USA 1986;83: 4913-4917.
3. Goedert M, Wischik CM, Crowther RA, Walker JE, Klug A: Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer's disease: Identification as the microtubule-associated protein tau. Proc Natl Acad Sci USA 1988;85:4051-4055.
4. Braak H, Braak E: Neuropil threads occur in the dendrites of tangle-bearing nerve cells. Neuropathol Appl Neurobiol 1988;14:39-44.
5. Wisniewski HM, Terry RD: Reexamination of the senile plaque. Prog Neuropathol 1973;2: 101-142.
6. Masters CL, Multhaup G, Sims G, Pottgiesser J, Martins RN, Beyreuther K: Neuronal origin of a cerebral amyloid: Neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels. EMBO J 1985;4:2757-2763.
7. Barcikowska M, Wisniewski HM, Bancher C, Grundke-Iqbal I: About the presence of paired helical filaments in dystrophic neurites participating in the plaque formation. Acta Neuropathol 1989;78:225-231.
8. Itagaki S, McGeer PL, Akiyama H, Zhu S, Sekoe D: Relationship of microglia and astrocytes to amyloid deposits of Alzheimer's disease. J Neuroimmunol 1989;24:173-182.
9. Schmidt ML, Lee VM-Y, Trojanowski JQ: Comparative epitope analysis of neuronal cytoskeletal proteins in Alzheimer's disease senile plaque neurites and neuropil threads. Lab Invest 1991;64:352-357.
10. Akiyama H: Inflammatory response in Alzheimer's disease. Tokohu J Exp Med 1994;174: 295-303.
11. Mackenzie IR, Hao C, Munoz DG: Role of microglia in senile plaque formation. Neurobiol Aging 1995;16:797-804.
12. Masliah E: Mechanisms of synaptic dysfunction in Alzheimer's disease. Histol Histopathol 1995;10:509-519.
13. Wang D, Munoz DG: Qualitative and quantitative differences in senile plaque dystrophic neurites of Alzheimer's disease and normal aged brain. J Neuropathol Exp Neurol 1995;54: 548-556.
14. Van de Nes JAP, Kamphorst W, Swaab DF: Arguments for and against the primary amyloid local induction hypothesis of the pathogenesis of Alzheimer's disease: in Cacabelos R, Winblad B (eds): Annals of Psychiatry. Barcelona, Prous Science, 1994, vol 4, pp 95-111.
15. Probst A, Basler V, Bron B, Ulrich J: Neuritic plaques in senile dementia of Alzheimer type: A Golgi analysis in the hippocampal region. Brain Res 1983;268:249-254.
16. Selkoe DJ: Amyloid protein and Alzheimer's disease. Sci Am 1991;265:68-78.
17. Masters CL, Beyreuther K: Molecular pathology of β/A4-amyloid protein precursor in Alzheimer's disease; in Cacabelos R, Winblad B (eds): Annals of Psychiatry. Barcelona, Prous Science, 1994, vol 4, pp 137-145.
18. Braak H, Braak E: Neuropathological staging of Alzheimer-related changes. Acta Neuropathol 1991;82:239-259.
19. Nagy Zs, Vatter-Bittner B, Braak H, Braak E, Yilmazer-Hanke DM, Schulz C, Hanke J: Staging of Alzheimer-type pathology: An interrater-intrarater study. Dementia Geriatr Cogn Disord 1997;8:248-251.
20. Crain BJ, Burger PC: The laminar distribution of neuritic plaques in the fascia dentata of patients with Alzheimer's disease. Acta Neuropathol 1988;76:87-93.
21. Hyman BT, Kromer LJ, van Hoesen GW: A direct demonstration of the perforant pathway terminal zone in Alzheimer's disease using the monoclonal antibody Alz-50. Brain Res 1988; 450:392-397.
22. Amaral DG, Insausti R: Hippocampal formation; in Paxinos G (ed): The Human Nervous System. New York, Academic Press. 1990, pp 711-755.
23. Braak H, Braak E, Yilmazer D, Bohl J: Functional anatomy of human hippocampal formation and related structures. J Clin Neurol 1996; 11:265-275.
24. Gallyas F: Silver staining of Alzheimer's neurofibrillary changes by means of physical development. Acta Morphol Acad Sci Hung 1971; 19:1-8.
25. Iqbal K, Braak H, Braak E, Grundke-Iqbal I: Silver labeling of Alzheimer neurofibrillary changes and brain beta-amyloid. J Histotechnol 1993;16:335-342.
26. Campbell SK, Switzer RC, Martin TL: Alzheimer's plaques and tangles: A controlled and enhanced silver-staining method. Soc Neurosci Abstr 1987;13:678.
27. Braak H, Braak E, Ohm T, Bohl J: Alzheimer's disease: Mismatch between amyloid plaques and neuritic plaques. Neurosci Lett 1989;103: 24-28.
28. Munoz DG, Wang D: Tangle-associated clusters: A new lesion in Alzheimer's disease and aging suggests that aggregates of dystrophic neurites are not necessarily associated with β/A4. Am J Pathol 1992;140:1167-1178.
29. Bancher C, Braak H, Fisher P, Jellinger KA: Neuropathological staging of Alzheimer lesions and intellectual status in Alzheimer's and Parkinson's disease patients. Neurosci Lett 1993; 162:179-182.
30. Shin R-W, Ogomori K, Kitamoto T, Tateishi J: Increased tau accumulation in senile plaques as a hallmark of Alzheimer's disease. Am J Pathol 1989;134:1365-1371.
31. Arai H, Lee VM-Y, Otvos L, Greenberg BD, Lowery DE, Sharma SK, Schmidt ML, Trojanowski JQ: Defined neurofilament, τ and β-amyloid precursor protein epitopes distinguish Alzheimer from non-Alzheimer senile plaques. Proc Natl Acad Sci USA 1990,87:2249-2253.
32. Yasuhara O, Kawamata T, Aimi Y, McGeer EG, McGeer PL: Two types of dystrophic neurites in senile plaques of Alzheimer's disease and elderly non-demented cases. Neurosci Lett 1994;171:73-76.
33. Mann DMA, Brown AMT, Prinja D, Jones D, Davies CA: A morphological analysis of senile plaques in the brains of non-demented persons of different ages using silver, immunocytochemical and lectin histochemical staining techniques. Neuropathol Appl Neurobiol 1990; 16:17-25.
34. Langui D, Probst A, Ulrich J: Alzheimer's changes in non-demented and demented patients: A statistical approach to their relationships. Acta Neuropathol Berl 1995;89:57-62.
35. Benzing WC, Brady DR, Mufson EJ, Armstrong DM: Evidence that transmitter-containing dystrophic neurites precede those containing paired helical filaments within senile plaques in the entorhinal cortex of nondemented elderly and Alzheimer's disease patients. Brain Res 1993;619:55-68.
36. Sparks DL, Liu H, Scheff SW, Coyne CM, Hunsaker JC: Temporal sequence of plaque formation in the cerebral cortex of non-demented individuals. J Neuropathol Exp Neurol 1993;52:135-142.
37. Yilmazer DM, Braak E, Braak H: Alzheimer-related changes within the amygdala in relationship to the gradual development of cortical pathology. Clin Neuropathol 1995;14:296.
38. Probst A, Anderton BH, Brion J-P. Ulrich J: Senile plaque neurites fail to demonstrate anti-paired helical filament and anti-microtubule-associated protein-tau immunoreactive proteins in the absence of neurofibrillary tangles in the neocortex. Acta Neuropathol 1989;77:430-436.
39. Terry RD, Hansen LA, De Teresa R, Davies P, Tobias H, Katzman R: Senile dementia of the Alzheimer type without neocortical neurofibrillary tangles. J Neuropathol Exp Neurol 1987;46:262-268.
40. Mirra SS, Heyman A, McKeel D, Sumi SM, Crain BJ, Borwnlee LM, Vogel FS, Hughes JP, van Belle G, Berg L: The consortium to establish a registry for Alzheimer's disease (CERAD). II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology 1991;41:479-486.
41. Price JL, Davis PB, Morris JC, White DL: The distribution of tangles, plaques and related immunohistochemical markers in healthy aging and Alzheimer's disease. Neurobiol Aging 1991;12:295-312.
42. Sheng JG, Mrak RE, Griffin WS: Microglial interleukin-1 alpha expression in brain regions in Alzheimer's disease: Correlation with neuritic plaque distribution. Neuropathol Appl Neurobiol 1995;21:290-301.
43. Yilmazer DM, Hanke J: Neuritic plaque formation in the hippocampus depends on the grade of amyloid deposition in the cerebral cortex in Alzheimer's disease. Clin Neuropathol 1996;15:304.
44. Dickson DW: The value of cross-sectional neuroanatomical studies as a conceptual framework for prospective clinicopathological studies. Neurobiol Aging 1997;18:382-386.
45. Frotscher M, Heimrich B, Deller T: Sprouting in the hippocampus is layer-specific. Trends Neurosci 1997;20:218-223.