A combined analysis of regional energy metabolism and immunohistochemical ischemic damage in the gerbil brain

Journal of Neurochemistry

Volumn 72, Issue 3, 1999, Pages 1232-1242

  Ueda, Hirokazu ^a,b   Tagawa, Kunio ^b,c   Furuya, Eisuke ^b,d   Matsumoto, Masayasu ^b   Yanagihara, Takehiko ^a,b  

^a MAYO CLINIC   (United States)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c OKAYAMA PREFECTURAL UNIVERSITY   (Japan)

^d OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

Cerebral ischemia; Energy metabolism; Immunohistochemistry; Microtubule associated protein; Selective vulnerability

Indexed keywords

MICROTUBULE ASSOCIATED PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN MITOCHONDRION; CAROTID ARTERY OBSTRUCTION; CONTROLLED STUDY; ENERGY METABOLISM; GERBIL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOHISTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; REPERFUSION;

ADENINE NUCLEOTIDES; ANIMALS; ARTERIAL OCCLUSIVE DISEASES; BRAIN; CAROTID ARTERY DISEASES; ENERGY METABOLISM; FEMALE; GERBILLINAE; GLUCOSE; IMMUNOHISTOCHEMISTRY; MALE; MICROTUBULE-ASSOCIATED PROTEINS; PHOSPHOCREATINE; REPERFUSION INJURY;

ANIMALIA; GERBILLINAE;

EID: 0033014179     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0721232.x     Document Type: Article

References (44)

1. Akai F. and Yanagihara T. (1994) Identity of the dorsal hippocampal region most vulnerable to cerebral ischemia. Brain Res. 603, 87-95.
2. Almeida A., Allen K. L., Bates T. E., and Clark J. B. (1995) Effect of reperfusion following cerebral ischemia on the activity of the mitochondrial respiratory chain in the gerbil brain. J. Neurochem. 65, 1698-1703.
3. Arai H., Passonneau J. V., and Lust W. D. (1986) Energy metabolism in delayed neuronal death of CA1 neurons of the hippocampus following transient ischemia in the gerbil. Metab. Brain Dis. 1, 263-278.
4. Bolaños J. P., Almeida A., Stewart V., Peuchen S., Land J. M., Clark J. B., and Heales S. J. R. (1997) Nitric oxide-mediated mitochondrial damage in the brain: mechanisms and implications for neurodegenerative diseases. J. Neurochem. 68, 2227-2240.
5. Endres M., Wang Z.-Q., Namura S., Waeber C., and Moskowitz M. A. (1997) Ischemic brain injury is mediated by the activation of poly (ADP-ribose) polymerase. J. Cereb. Blood Flow Metab. 17, 1143-1151.
6. Hatakeyama T., Matsumoto M., Brengman J. M., and Yanagihara T. (1988) Immunohistochemical investigation of ischemic and post-ischemic damage after bilateral carotid occlusion in gerbils. Stroke 19, 1526-1534.
7. Ito U., Spatz M., Walker J. T. Jr., and Klatzo I. (1975) Experimental cerebral ischemia in mongolian gerbils I. Light microscopic observations. Acta Neuropathol. 32, 209-223.
8. Kamiike W., Watanabe F., Hashimoto T., Tagawa K., Ikeda Y., Nakao K., and Kawashima Y. (1982) Changes in cellular levels of ATP and its catabolites in ischemic rat liver. J. Biochem. (Tokyo) 91, 1349-1356.
9. Kirino T. (1982) Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res. 239, 57-69.
10. Kobayashi M., Lust D., and Passonneau J. V. (1977) Concentrations of energy metabolites and cyclic nucleotides during and after bilateral ischemia in the gerbil cerebral cortex. J. Neurochem. 29, 53-59.
11. Kogure K. and Alonso O. F. (1978) A pictorial representation of endogenous brain ATP by a bioluminescent method. Brain Res. 154, 273-284.
12. Levy D. E. and Duffy T. E. (1975) Effect of ischemia on energy metabolism in the gerbil cerebral cortex. J. Neurochem. 24, 1287-1289.
13. Levy D. E. and Duffy T. E. (1977) Cerebral energy metabolism during transient ischemia and recovery in the gerbil. J. Neurochem. 28, 63-70.
14. Li J.-Y., Ueda H., Seiyama A., Nakano M., Matsumoto M., and Yanagihara T. (1997) A near-infrared spectroscopic study of cerebral ischemia and ischemic tolerance in gerbils. Stroke 28, 1451-1457.
15. Ljunggren B., Ratcheson R. A., and Siesjö B. K. (1974) Cerebral metabolic state following complete compression ischemia. Brain Res. 73, 291-307.
16. Lowry O. H. and Passonneau J. V. (1972) A Flexible System of Enzymatic Analysis. Academic Press, New York and London.
17. Lowry O. H., Passonneau J. V., Hasselberger F. X., and Schulz D. W. (1964) Effect of ischemia on known substrates and cofactors of the glycolytic pathway in brain. J. Biol. Chem. 239, 18-30.
18. Matsumoto M., Hatakeyama T., Yamamoto K., and Yanagihara T. (1987) A combined method for measurement of cerebral blood flow and immunohistochemistry for investigation of cerebral ischemia. Brain Res. 424, 231-238.
19. Matsumoto M., Hatakeyama T., Morimoto K., and Yanagihara T. (1990) Cerebral blood flow and neuronal damage during progressive cerebral ischemia in gerbils. Stroke 21, 1470-1477.
20. Mrsulja B. B., Ueki Y., and Lust W. D. (1986) Regional metabolite profiles in early stages of global ischemia in the gerbil. Metab. Brain Dis. 1, 205-220.
21. Munekata K. and Hossmann K.-A. (1987) Effect of 5-minute ischemia on regional pH and energy state of the gerbil brain: relation to selective vulnerability of the hippocampus. Stroke 18, 412-417.
22. 31P NMR studies on the isolated perfused mandibular gland of the rat. Jpn. J. Physiol. 37, 411-423.
23. Nowak T. S. Jr., Fried R. L., Lust W. D., and Passonneau J. V. (1985) Changes in brain energy metabolism and protein synthesis following transient bilateral ischemia in the gerbil. J. Neurochem. 44, 487-494.
24. Onodera H., Iijima K., and Kogure K. (1986) Mononucleotide metabolism in the rat brain after transient ischemia. J. Neurochem. 46, 1704-1710.
25. Passonneau J. V. and Lauderdale V. R. (1974) A comparison of three methods of glycogen measurement in tissues. Anal. Biochem. 60, 405-412.
26. Pontén U., Ratcheson R. A., Salford L. G., and Siesjö B. K. (1973) Optimal freezing conditions for cerebral metabolites in rats. J. Neurochem. 21, 1127-1138.
27. Pulsinelli W. A. and Duffy T. E. (1983) Regional energy balance in rat brain after transient forebrain ischemia. J. Neurochem. 40, 1500-1503.
28. Pulsinelli W. A., Brierley J. B., and Plum F. (1982) Temporal profile of neuronal damage in a model of transient forebrain ischemia. Ann. Neurol. 11, 491-498.
29. Siesjö B. K. and Wieloch T. (1985) Cerebral metabolism in ischemia: neurochemical basis for therapy. Br. J. Anaesth. 57, 47-62.
30. Suzuki R., Yamaguchi T., Kirino T., Orzi F., and Klatzo I. (1983) The effects of 5-minute ischemia in mongolian gerbils. I. Blood-brain barrier, cerebral blood flow, and local cerebral glucose utilization changes. Acta Neuropathol. 60, 207-216.
31. Takahashi K., Greenberg J. H., Jackson P., Maclin K., and Zhang J. (1997) Neuroprotective effects of inhibiting poly (ADP-ribose) synthetase on focal cerebral ischemia in rats. J. Cereb. Blood Flow Metab. 17, 1137-1142.
32. Tomimoto H. and Yanagihara T. (1992) Immunoelectron microscopic study of tubulin and microtubule-associated proteins after transient cerebral ischemia in gerbils. Acta Neuropathol. 84, 394-399.
33. Tomimoto H. and Yanagihara T. (1993) Immunoelectron microscopic investigation of creatine kinase-BB isoenzyme after cerebral ischemia in gerbils. Acta Neuropathol. 86, 447-455.
34. Tomimoto H. and Yanagihara T. (1994) Golgi electron microscopic study of the cerebral cortex after transient cerebral ischemia and reperfusion in the gerbil. Neuroscience 63, 957-967.
35. Ueda H., Hashimoto T., Furuya E., Tagawa K., Kitagawa K., Matsumoto M., Yoneda S., Kimura K., and Kamada T. (1988) Changes in aerobic and anaerobic ATP-synthesizing activities in hypoxic mouse brain. J. Biochem. (Tokyo) 104, 81-86.
36. Ueda H., Matsumoto M., Nakamura M., Tagawa K., and Yanagihara T. (1993) A combined method for the regional analysis of high-energy metabolites and immunohistochemistry for the investigation of cerebral ischemia. (Abstr.) J. Cereb. Blood Flow Metab. 13 (Suppl. 1), S559.
37. Ueda H., Matsumoto M., Nakano M., Li J.-Y., Yoshida Y., and Yanagihara T. (1995) N-Acetyl aspartate levels in delayed neuronal death in the hippocampus of the gerbil brain. (Abstr.) J. Neurochem. 64 (Suppl.), S13.
38. Yamamoto K., Hayakawa T., Mogami H., Akai F., and Yanagihara T. (1990) Ultrastructural investigation of the CA1 region of the hippocampus after transient ischemia in gerbils. Acta Neuropathol. 80, 487-492.
39. Yanagihara T. (1990) Immunohistochemical assessment of cerebral ischemia, in Cerebral Ischemia and Resuscitation (Schurr A. and Rigor B. M., eds), pp. 389-412. CRC Press, Boca Raton, Florida.
40. Yanagihara T. (1991) Metabolic derangement and cell damage in cerebral ischemia with emphasis on protein and nucleic acid metabolism, in Advances in Brain Resuscitation (Takeshima H., Siesjö B. K., and Miller J. D., eds), pp. 77-98. Springer-Verlag, Tokyo.
41. Yanagihara T., Yoshimine T., Morimoto K., Yamamoto K., and Homburger H. A. (1985) Immunohistochemical investigation of cerebral ischemia in gerbils. J. Neuropathol. Exp. Neurol. 44, 204-215.
42. Yanagihara T., Brengman J. M., and Mushynski W. E. (1990) Differential vulnerability of microtubule components in cerebral ischemia. Acta Neuropathol. 80, 499-505.
43. Yasumoto Y., Passonneau J. V., Feussner G., and Lust W. D. (1988) Metabolic alterations in fiber layers of the CA 1 region of the gerbil hippocampus following short-term ischemia: high-energy phosphates, glucose-related metabolites, and amino acids. Metab. Brain Dis. 3, 133-149.
44. Zhang J., Dawson V. L., Dawson T. M., and Snyder S. H. (1994) Nitric oxide activation of poly (ADP-ribose) synthetase in neurotoxicity. Science 263, 687-689.