Inhibition of GABA-gated chloride channels by 12,14-dichlorodehydroabietic acid in mammalian brain

British Journal of Pharmacology

Volumn 126, Issue 5, 1999, Pages 1123-1132

  Nicholson, Russell A ^a   Lees, George ^b   Zheng, Jian ^a   Verdon, Bernard ^b  

^a SIMON FRASER UNIVERSITY   (Canada)

^b NONE

Author keywords

12,14 Dichlorodehydroabietic acid; 36Cl uptake; Cortical neurones; GABA receptor; Mammalian brain; Patch clamp; Synaptoneurosomes; 3H EBOB binding

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; BENZOIC ACID DERIVATIVE; CALCIUM ION; CHLORIDE CHANNEL; DEHYDROABIETIC ACID; MUSCIMOL; PICROTOXININ;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; BRAIN CORTEX; BRAIN SYNAPTOSOME; CELL MEMBRANE DEPOLARIZATION; CHLORIDE CURRENT; CHLORIDE TRANSPORT; CONTROLLED STUDY; DRUG BINDING SITE; DRUG RECEPTOR BINDING; EMBRYO; EXCITATORY POSTSYNAPTIC POTENTIAL; INHIBITORY POSTSYNAPTIC POTENTIAL; MALE; MOUSE; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; RADIORECEPTOR ASSAY; RAT; RECEPTOR AFFINITY; SYNAPSE;

EID: 0033013292     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702419     Document Type: Article

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