Caloric restriction abolishes enhanced metabolic efficiency induced by ectopic agouti protein in yellow mice

Proceedings of the Society for Experimental Biology and Medicine

Volumn 221, Issue 2, 1999, Pages 99-104

  Wolff, George L ^a,b   Kodell, Ralph L ^a   Kaput, James A ^c   Visek, Willard J ^d  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c Houston Biotechnology Incorporated   (United States)

^d UNIVERSITY OF ILLINOIS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGOUTI PROTEIN; GLUCOSE; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; BRAIN WEIGHT; CALORIC RESTRICTION; CONFERENCE PAPER; CONTROLLED STUDY; FEMALE; FOOD INTAKE; GLUCOSE BLOOD LEVEL; MOUSE; NONHUMAN; OBESITY; WEIGHT GAIN;

AGOUTI; ANIMALIA;

EID: 0033013066     PISSN: 00379727     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1525-1373.1999.d01-61.x     Document Type: Conference Paper

References (19)

1. Duhl DM, Vrieling H, Miller KA, Wolff GL, Barsh GS. Neomorphic agouti mutations in obese yellow mice. Nat Genet 8:59-65, 1994.
2. Miltenberger RJ, Mynatt RL, Wilkinson JE, Woychik RP. The role of the agouti gene in the yellow obese syndrome. J Nutr 127:19025-1907S, 1997.
3. vy/- mice: Ectopic expression of the agouti gene. FASEB J 8:479-488, 1994.
4. Lu D, Willard D, Patel IR, Kadwell S, Overton L, Kost T, Luther M, Chen W, Woychik RP, Cone RD. Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor. Nature 371:799-802, 1994.
5. Mountjoy KG, Mortrud MT, Low MJ, Simerly RB, Cone RD. Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain. Mol Endocrinol 8:1298-1308, 1994.
6. Zemel MB, Kim JH, Woychik RP, Michaud EJ, Kadwell SH, Patel IR, Wilkison WO. Agouti regulation of intracellular calcium: Role in the insulin resistance of viable yellow mice. Proc Natl Acad Sci U S A 92:4733-4737, 1995.
7. 2+-sensitive adenylyl cyclases. Adv Second Messenger Phosphoprotein Res 32:23-51, 1998.
8. Wolff GL. Variability in gene expression and tumor formation within genetically homogeneous animal populations in bioassays. Fundam Appl Toxicol 29:175-184, 1996.
9. Kwon HY, Bultman SJ, Löffler C, Chen W-J, Furdon PJ, Powell JG, Usala A-L, Wilkison W, Hansmann I, Woychik RP. Molecular structure and chromosomal mapping of the human homolog of the agouti gene. Proc Natl Acad Sci U S A 91:9760-9764, 1994.
10. Wilson BD, Ollmann MM, Kang L, Stoffel M, Bell GI, Barsh GS. Structure and function of ASP, the human homolog of the mouse agouti gene. Hum Mol Genet 4:223-230, 1995.
11. Paisley EA, Park EI, Swartz DA, Mangian HJ, Visek WJ, Kaput J. Temporal regulation of serum lipids and stearoyl CoA desaturase and lipoprotein lipase mRNA in BALB/cHnn mice. J Nutr 126:2730-2737, 1996.
12. SAS/STAT, User's Guide, Version 6 (4th ed). Cary, NC: SAS Institute, Vol 2:pp 891-996, 1993.
13. ya) and non-yellow (aa) mice in parabiosis. Genetics 48:1041-1058, 1963.
14. 1 hybrid mice to the same diets: Glucose tolerance, weight gain, and adipocyte cellularity. Int J Obes Relat Metab Disord 12:305-320, 1988.
15. y gene on pulmonary tumors in mice by alteration of its effect on normal growth. J Natl Cancer Inst 27:1189-1196, 1961.
16. Wolff GL, Roberts DW, Morrissey RL, Greenman DL, Allen RR, Campbell WL, Bergman H, Nesnow S, Frith CH. Tumorigenic responses to lindane in mice: Potentiation by a dominant mutation. Carcinogenesis 8:1889-1897, 1987.
17. Wolff GL. Obesity as a pleiotropic effect of gene action. J Nutr 127:18975-19015, 1997.
18. Wolff GL. Serum levels of somatomedin-C/insulin-like growth factor I in yellow and non-yellow mice. NCTR Tech Rept For Expt 6338:1-13, 1985.
19. D'Ercole AJ, Applewhite GT, Underwood LE. Evidence that somatomedin is synthesized by multiple tissues in the fetus. Dev Biol 75:315-328, 1980.