Pneumococcal conjugate vaccine primes for polysaccharide-inducible IgG2 antibody response in children with recurrent otitis media acuta

Journal of Infectious Diseases

Volumn 179, Issue 5, 1999, Pages 1152-1156

  Breukels, Mijke A ^a   Rijkers, Ger T ^a   Voorhorst Ogink, Marleen M ^a   Zegers, Ben J M ^a   Sanders, Lieke A M ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; PNEUMOCOCCUS VACCINE; POLYSACCHARIDE;

ADOLESCENT; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; CHILD; CLINICAL ARTICLE; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; OTITIS MEDIA; PRIORITY JOURNAL; RECURRENT INFECTION; VACCINATION;

ANTIBODIES, BACTERIAL; BACTERIAL VACCINES; CHILD; CHILD, PRESCHOOL; HUMANS; IMMUNIZATION, SECONDARY; IMMUNOGLOBULIN G; MENINGOCOCCAL VACCINES; OTITIS MEDIA; PNEUMOCOCCAL INFECTIONS; PNEUMOCOCCAL VACCINES; POLYSACCHARIDES, BACTERIAL; RECURRENCE; SEROTYPING; STREPTOCOCCUS PNEUMONIAE; VACCINATION; VACCINES, CONJUGATE;

EID: 0033013043     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/314705     Document Type: Article

References (20)

1. 1. Klein JO. The epidemiology of pneumococcal disease in infants and children. Rev Infect Dis 1981;3:246-53.
2. 2. Freijd A, Hammerström L, Persson MAA, Smith CIE. Plasma anti-pneumococcal antibody activity of the IgG class and subclasses in otitis prone children. Clin Exp Immunol 1984;56:233-8.
3. 3. Sanders LA, Rijkers GT, Tenbergen-Meekes AM, Voorhorst-Ogink MM, Zegers BJ. Immunoglobulin isotype specific responses to pneumococcal polysaccharide vaccine in patients with recurrent respiratory tract infections. Pediatr Res 1995;37:812-9.
4. 4. Kayhty H, Ahman H, Ronnberg PR, Tillikainen R, Eskola J. Pneumococcal polysaccharide-meningococcal outer membrane protein complex conjugate vaccine is immunogenic in infants and children. J Infect Dis 1995; 172:1273-8.
5. 5. Anderson EL, Kennedy DJ, Geldmacher KM, Donnelly J, Mendelman PM. Immunogenicity of heptavalent pneumococcal conjugate vaccine in infants. J Pediatr 1996;128:649-53.
6. 6. O'Brien KL, Steinhoff MC, Edwards K, Keyserling H, Thoms ML, Madore D. Immunologic priming of young children by pneumococcal glycoprotein conjugate, but not polysaccharide, vaccines. Pediatr Infect Dis J 1996;15: 425-30.
7. 7. Casselbrant ML, Kaleida PH, Rockette HE, et al. Efficacy of antimicrobial prophylaxis and of tympanostomy tube insertion for prevention of recurrent acute otitis media: results of a randomized clinical trial [see comments]. Pediatr Infect Dis J 1992;11:278-86.
8. 8. Siber GR, Ambrosino DM, McIver J, et al. Preparation of human hyperimmune globulin to Haemophilus influenzae b, Streptococcus pneumoniae, and Neisseria meningitidis. Infect Immun 1984;45:248-54.
9. 9. Rynnel-Dagoo B, Freijd A, Hammarstrom L, Oxelius V, Persson MA, Smith CI. Pneumococcal antibodies of different immunoglobulin subclasses in normal and IgG subclass deficient individuals of various ages. Acta Otolaryngol (Stockh) 1986;101:146-51.
10. 10. French MA, Denis KA, Dawkins R, Peter JB. Severity of infections in 1gA deficiency: correlation with decreased serum antibodies to pneumococcal polysaccharides and decreased serum IgG2 and/or IgG4. Clin Exp Immunol 1995;100:47-53.
11. 11. Rijkers GT, Sanders LA, Zegers BJ. Anti-capsular polysaccharide antibody deficiency states. Immunodeficiency 1993;5:1-21.
12. 12. Gray BM, Dillon HC. Clinical and epidemiologic studies of pneumococcal infection in children. Pediatr Infect Dis 1986;5:201-7.
13. 13. Pabst HF, Kreth HW. Ontogeny of the immune response as a basis of childhood disease. J Pediatr 1980;97:519-34.
14. 14. Paradiso PR, Lindberg AA. Glycoconjugate vaccines: future combinations. Dev Biol Stand 1996;87:269-75.
15. 15. Kayhty H, Eskola J. New vaccines for the prevention of pneumococcal infections. Emerg Infect Dis 1996;2:289-98.
16. 197 in United States infants. Pediatrics 1998;101:604-11.
17. 17. Dagan R, Melamed R, Zamir O, Leroy O. Safety and immunogenicity of tetravalent pneumococcal vaccines containing 6B, 14, 19F and 23F polysaccharides conjugated to either tetanus toxoid or diphtheria toxoid in young infants and their boosterability by native polysaccharide antigens. Pediatr Infect Dis J 1997;16:1053-9.
18. 197 vaccines: effect of saccharide size on immunogenicity and interactions with simultaneously administered vaccines. J Infect Dis 1997;176:445-55.
19. 19. O'Brien KL, Steinhoff MC, Edwards K, Keyserling H, Thoms ML, Madore D. Immunologic priming of young children by pneumococcal glycoprotein conjugate, but not polysaccharide, vaccines. Pediatr Infect Dis J 1996;15: 425-30.
20. 20. Epstein MM, Gruskay F. Selective deficiency in pneumococcal antibody response in children with recurrent infections. Ann Allergy Asthma Immunol 1995;75:125-31.