Use of indomethacin in Langerhans cell histiocytosis

Medical and Pediatric Oncology

Volumn 32, Issue 4, 1999, Pages 247-249

  Munn, Stephanie E ^a   Olliver, Lucy ^b   Broadbent, Valerie ^c   Pritchard, Jon ^b  

^a KING S COLLEGE HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

Eosinophilic granuloma of bone; Indomethacin; Langerhans cell histiocytosis; NSAIDs; Prostaglandins; Treatment

Indexed keywords

INDOMETACIN; PROSTAGLANDIN E2; PROSTAGLANDIN INHIBITOR;

ANTIINFLAMMATORY ACTIVITY; ARACHIDONIC ACID METABOLISM; ARTICLE; BONE DISEASE; BONE PAIN; CELL PROLIFERATION; CHILD; DRUG EFFECT; ENZYME INHIBITION; FEMALE; HISTIOCYTOSIS; HUMAN; INFANT; LANGERHANS CELL; MAJOR CLINICAL STUDY; MALE; OSTEOLYSIS; PRIORITY JOURNAL;

ADOLESCENT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BONE NEOPLASMS; CHILD; CHILD, PRESCHOOL; FEMALE; HISTIOCYTOSIS, LANGERHANS-CELL; HUMANS; INDOMETHACIN; MALE; PROSTAGLANDIN ANTAGONISTS; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 0033012521     PISSN: 00981532     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-911X(199904)32:4<247::AID-MPO1>3.0.CO;2-J     Document Type: Article

References (6)

1. Brown RE, Bowman WP, d'Cruz CA, et al. Endoperoxidation, hyperprostaglandinaemia and hyperlipidaemia in a case of erythrophagocytic lymphohistiocytosis: reversal with VP16 and indomethacin. Cancer 1987;60:2388-2393.
2. Arenza-Seisdedos F, Barbey S, Virelizier JL, et al. Histiocytosis X, purified T6Y cells from bone granuloma produce interleukin 1 and prostaglandin E2 in culture. J Clin Invest 1986;77:326-329.
3. Gonzalez-Crussi F, Hsueh W, Wiederhold MD. Prostaglandins in histiocytosis X: PG synthesis by histiocytosis-X cells. Am J Clin Pathol 1981;75:243-253.
4. Broadbent V, Egeler RM, Nesbit ME. Langerhans cell histiocytosis: clinical and epidemiological aspects. Br J Cancer 1994;70: S11-S16.
5. Writing Group of the Histiocytosis Society. Histiocytosis syndromes in children. Lancet 1987;1:208-209.
6. McLean TW, Pritchard J. Langerhans cell histiocytosis and hypercalcaemia: clinical response to indomethacin. J Paediatr Haematol Oncol 1996;18:318-320.