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Volumn 20, Issue 1, 1999, Pages 67-76

In vivo stability and metabolism of 99tcm-labelled anti-cd4 monoclonal antibodies and fab’ fragments

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN DERIVATIVE; CYSTEINE; GLUTATHIONE; IMMUNOGLOBULIN F(AB) FRAGMENT; MONOCLONAL ANTIBODY; TECHNETIUM 99M;

EID: 0033012358     PISSN: 01433636     EISSN: 14735628     Source Type: Journal    
DOI: 10.1097/00006231-199901000-00011     Document Type: Article
Times cited : (4)

References (23)
  • 1
    • 0025183991 scopus 로고
    • Horneff Get al. Imaging rheumatoid arthritis specifically with technetium 99m CD4-specific (T-helper lymphocytes) antibodies
    • Becker W, Emmrich F, Horneff Get al. Imaging rheumatoid arthritis specifically with technetium 99m CD4-specific (T-helper lymphocytes) antibodies. Eur J Nucl Med 1990; 17: 156-159.
    • (1990) Eur J Nucl Med , vol.17 , pp. 156-159
    • Becker, W.1    Emmrich, F.2
  • 2
    • 84936910238 scopus 로고
    • Comparison of ’relabeled specific murine anti-CD4 monoclonal antibodies and nonspecific human immunoglobulin for imaging of inflamed joints in rheumatoid arthritis
    • Kinne RW, Becker W, Schwab J et al. Comparison of ’relabeled specific murine anti-CD4 monoclonal antibodies and nonspecific human immunoglobulin for imaging of inflamed joints in rheumatoid arthritis. Nucl Med Commun 1993; 14: 667-675.
    • (1993) Nucl Med Commun , vol.14 , pp. 667-675
    • Kinne, R.W.1    Becker, W.2    Schwab, J.3
  • 3
    • 0028144311 scopus 로고
    • Imaging of rheumatoid arthritis joints with 99Tcm-labeled specific anti-CD4 and non-specific immunoglobulins: Case report
    • Kinne RW, Becker W, Schwab J et al. Imaging of rheumatoid arthritis joints with 99Tcm-labeled specific anti-CD4 and non-specific immunoglobulins: Case report. Eur J Nucl Med 1994; 21: 178-180.
    • (1994) Eur J Nucl Med , vol.21 , pp. 178-180
    • Kinne, R.W.1    Becker, W.2    Schwab, J.3
  • 4
    • 0027505659 scopus 로고
    • Joint uptake and body distribution of a technetium-99m-labeled anti-rat-CD4 monoclonal antibody in rat adjuvant arthritis
    • Kinne RW, Becker W, Simon G et al. Joint uptake and body distribution of a technetium-99m-labeled anti-rat-CD4 monoclonal antibody in rat adjuvant arthritis. J Nucl Med 1993; 34: 92-98.
    • (1993) J Nucl Med , vol.34 , pp. 92-98
    • Kinne, R.W.1    Becker, W.2    Simon, G.3
  • 5
    • 0028880803 scopus 로고
    • Koscheck et al. Rat adjuvant arthritis: Imaging with technetium-99m-anti-CD4 Fab’ fragments
    • Kinne RW, Becker W, Koscheck et al. Rat adjuvant arthritis: Imaging with technetium-99m-anti-CD4 Fab’ fragments. J Nucl Med 1995; 36: 2268-2275.
    • (1995) J Nucl Med , vol.36 , pp. 2268-2275
    • Kinne, R.W.1    Becker, W.2
  • 6
    • 0025057548 scopus 로고
    • Preclinical evaluation of an ’instant’ 99Tcm-labeling kit for antibody imaging
    • Hansen HJ, Jones AL, Sharkey RM et al. Preclinical evaluation of an ’instant’ 99Tcm-labeling kit for antibody imaging. Cancer Res 1990; 50 (suppl): 794s-798s.
    • (1990) Cancer Res , vol.50 , pp. 794s-798s
    • Hansen, H.J.1    Jones, A.L.2    Sharkey, R.M.3
  • 7
    • 0029565958 scopus 로고
    • Long-term amelioration of rat adjuvant arthritis following systemic elimination of macrophages by clodronate-containing liposomes
    • Kinne RW, Schmidt-Weber CB, Hoppe R et al. Long-term amelioration of rat adjuvant arthritis following systemic elimination of macrophages by clodronate-containing liposomes. Arthritis Rheum 1995; 38: 1777-1790.
    • (1995) Arthritis Rheum , vol.38 , pp. 1777-1790
    • Kinne, R.W.1    Schmidt-Weber, C.B.2    Hoppe, R.3
  • 9
    • 0028892309 scopus 로고
    • Targeting of liver metastases of colorectal cancer with IgG, F(Ab’)2 and Fab’ anti-carcinoembryonic antigen antibodies labeled with 99Tcm: The role of metabolism and kinetics
    • Behr T, Becker W, Hannappel E, Goldenberg DM, Wolf F. Targeting of liver metastases of colorectal cancer with IgG, F(ab’)2 and Fab’ anti-carcinoembryonic antigen antibodies labeled with 99Tcm: The role of metabolism and kinetics. Cancer Res 1995; 55 (suppl.): 5777s-5785s.
    • (1995) Cancer Res , vol.55 , pp. 5777s-5785s
    • Behr, T.1    Becker, W.2    Hannappel, E.3    Goldenberg, D.M.4    Wolf, F.5
  • 10
    • 0027949083 scopus 로고
    • Structural modifications of monoclonal antibodies following direct versus indirect labelling with 99Tcm: Does fragmentation really occur?
    • Behr T, Becker W, Hannappel E, Wolf F. Structural modifications of monoclonal antibodies following direct versus indirect labelling with 99Tcm: Does fragmentation really occur? Nucl Med Commun 1994; 15: 865-870.
    • (1994) Nucl Med Commun , vol.15 , pp. 865-870
    • Behr, T.1    Becker, W.2    Hannappel, E.3    Wolf, F.4
  • 11
    • 85026156332 scopus 로고    scopus 로고
    • Spezifische Darstellung entzündeter Gelenke in der Ratten-Adjuvans-Arthritis mit einem Technetium-99m markierten anti-CD4 Fab’-Frag-ment
    • Koscheck, I. Inaugural dissertation, Spezifische Darstellung entzündeter Gelenke in der Ratten-Adjuvans-Arthritis mit einem Technetium-99m markierten anti-CD4 Fab’-Frag-ment, Friedrich-Alexander-Universität Erlangen-Nürnberg, 25 April 1996.
    • (1996) Friedrich-Alexander-Universität Erlangen-Nürnberg , pp. 25
    • Koscheck, I.I.D.1
  • 12
    • 0026612798 scopus 로고
    • The stability of technetium-99m directly labeled to a Fab’ antibody via stannous ion and mercaptoethanol reduction
    • Mardirossian G, Wu C, Ruschkowski M, Hnatowich DJ. The stability of technetium-99m directly labeled to a Fab’ antibody via stannous ion and mercaptoethanol reduction. Nucl Med Commun 1992; 13: 503-512.
    • (1992) Nucl Med Commun , vol.13 , pp. 503-512
    • Mardirossian, G.1    Wu, C.2    Ruschkowski, M.3    Hnatowich, D.J.4
  • 14
    • 0027251628 scopus 로고
    • Internalization and degradation of anti-CD4 monoclonal antibodies bound to human peripheral blood lymphocytes
    • Morel P, Vincent C, Wijdenes J, Revillard D. Internalization and degradation of anti-CD4 monoclonal antibodies bound to human peripheral blood lymphocytes. Mol Immunol 1993; 30: 649-657.
    • (1993) Mol Immunol , vol.30 , pp. 649-657
    • Morel, P.1    Vincent, C.2    Wijdenes, J.3    Revillard, D.4
  • 15
    • 85026171733 scopus 로고    scopus 로고
    • Gel filtration, theory and practice. Pharmacia Fine Chemicals, Company publication
    • Gel filtration, theory and practice. Pharmacia Fine Chemicals, Company publication.
  • 16
    • 0029143994 scopus 로고
    • Reduction of the renal uptake of radiolabeled monoclonal antibody fragments by cationic amino acids and their derivatives
    • Behr TM, Sharkey RM, Juweid ME et al. Reduction of the renal uptake of radiolabeled monoclonal antibody fragments by cationic amino acids and their derivatives. Cancer Res 1995; 55: 3825-3834.
    • (1995) Cancer Res , vol.55 , pp. 3825-3834
    • Behr, T.M.1    Sharkey, R.M.2    Juweid, M.E.3
  • 17
    • 0013592343 scopus 로고
    • Nierenfunktion, Wasser und Elektrolythaushalt
    • Steinhausen M, ed., München: Bergmann Verlag
    • Steinhausen M. Nierenfunktion, Wasser und Elektrolythaushalt. In: Steinhausen M, ed. Lehrbuch der vegetativen Physiologie. München: Bergmann Verlag, 1984: 230-278.
    • (1984) Lehrbuch Der Vegetativen Physiologie , pp. 230-278
    • Steinhausen, M.1
  • 18
    • 0013995970 scopus 로고
    • Über die Größe der Porenäquivalente in isolierten Basalmembranen der Rattennierenrinde
    • Gekle G, Von Bruchhausen F, Fuchs G. Über die Größe der Porenäquivalente in isolierten Basalmembranen der Rattennierenrinde. Pflügers Archiv 1966; 289: 180-190.
    • (1966) Pflügers Archiv , vol.289 , pp. 180-190
    • Gekle, G.1    Von Bruchhausen, F.2    Fuchs, G.3
  • 20
    • 0025340481 scopus 로고
    • Urinary N-acetyl-beta-D-glucosaminidase as a marker of renal injury in adjuvant arthritis
    • Franch MA, Moreno JJ, Castell M, Queralt J. Urinary N-acetyl-beta-D-glucosaminidase as a marker of renal injury in adjuvant arthritis. Res Exp Med (Berl) 1990; 190: 213-218.
    • (1990) Res Exp Med (Berl) , vol.190 , pp. 213-218
    • Franch, M.A.1    Moreno, J.J.2    Castell, M.3    Queralt, J.4
  • 21
    • 0025719051 scopus 로고
    • Anomalies in reduction-mediated technetium-99m-labelling of monoclonal antibodies
    • Pimm MV, Rajput RS, Frier M, Gribben SJ. Anomalies in reduction-mediated technetium-99m-labelling of monoclonal antibodies. Eur J Nucl Med 1991; 18: 973-976.
    • (1991) Eur J Nucl Med , vol.18 , pp. 973-976
    • Pimm, M.V.1    Rajput, R.S.2    Frier, M.3    Gribben, S.J.4
  • 22
    • 0027204992 scopus 로고
    • In vivo instability of reduction-mediated 99Tcm-labeled monoclonal antibody
    • Sakahara H, Saga T, Endo K et al. In vivo instability of reduction-mediated 99Tcm-labeled monoclonal antibody. Nucl Med Biol 1993; 20: 617-623.
    • (1993) Nucl Med Biol , vol.20 , pp. 617-623
    • Sakahara, H.1    Saga, T.2    Endo, K.3
  • 23
    • 0027463977 scopus 로고
    • Directly and indirectly technetium-99m-labeled antibodies: A comparison of in vitro and animal in vivo properties
    • Hnatowich DJ, Madirossian G, Ruschowski M, Fogarasi M, Virzi F, Winnard P Directly and indirectly technetium-99m-labeled antibodies: A comparison of in vitro and animal in vivo properties. J Nucl Med 1993; 34: 109-119.
    • (1993) J Nucl Med , vol.34 , pp. 109-119
    • Hnatowich, D.J.1    Madirossian, G.2    Ruschowski, M.3    Fogarasi, M.4    Virzi, F.5    Winnard, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.