Growth of Candida boidinii in a methanol-limited continuous culture and the formation of methanol-degrading enzymes

Journal of Biotechnology

Volumn 72, Issue 1-2, 1999, Pages 127-139

  Aggelis, G ^a   Fakas, S ^a   Melissis, S ^a   Clonis, Y D ^a  

^a UNIVERSITY OF ATHENS   (Greece)

Author keywords

Candida boidinii; Formaldehyde dehydrogenase; Formate dehydrogenase; Methanol; Methanol oxidase

Indexed keywords

BIOGAS; BIOSYNTHESIS; CATALYST ACTIVITY; CONTINUOUS CELL CULTURE; ENZYMES; GROWTH KINETICS; METHANOL; OXIDATION; YEAST;

MONOD EQUATION;

PLANT CELL CULTURE;

FORMALDEHYDE DEHYDROGENASE; FORMATE DEHYDROGENASE; METHANOL; OXIDOREDUCTASE;

ARTICLE; BIOMASS; CANDIDA BOIDINII; CELL CULTURE; CONTINUOUS CULTURE; CULTURE MEDIUM; ENZYME ACTIVITY; ENZYME SYNTHESIS; GROWTH RATE; IN VITRO STUDY; PRIORITY JOURNAL;

CANDIDA BOIDINII;

EID: 0033012011     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-1656(99)00102-9     Document Type: Article

References (29)

1. Andrews J.F. A mathematical model for the continuous culture of microorganisms utilizing inhibitory substrates. Biotechnol. Bioeng. 10:1968;707-723.
2. Asthana H., Humphrey A.E., Moritz V. Growth of yeast on methanol as the sole carbon source. Biotechnol. Bioeng. 13:1971;923-929.
3. Beste H., Fackeldey M., Willems M., Stockmann L., Weuster-Botz D. Optimization of fermentation medium composition in substrate-controlled continuous stirred tank reactors. Chem. Eng. Technol. 20:1997;403-413.
4. Bradford M. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
5. Chenault H.K., Whitesides G.M. Regeneration of nicotinamide cofactors for use in organic synthesis. Appl. Biochem. Biotechnol. 14:1986;147-197.
6. Egli T., van Dijken J.P., Veenhuis M., Harder W., Fiechter A. Methanol metabolism in yeasts: regulation of the synthesis of catabolic enzymes. Arch. Microbiol. 124:1980;115-121.
7. Egli T., Haltmeier T., Fiechter A. Regulation of the synthesis of methanol oxidizing enzymes in Kloeckera sp. 2201 and Hansenula polymorpha, a comparison. Arch. Microbiol. 131:1982;174-175.
8. Egli T., Lindley N. Mitochondrial activities in the methylotrophic yeast Kloeckera sp. 2201 during growth with glucose and/or methanol. J. Gen. Microbiol. 130:1984;3239-3249.
9. Hazeu W., de Bruyn J.C., Bos P. Methanol assimilation by yeasts. Arch. Microbiol. 87:1972;185-188.
10. Hristozova T., Michailova L., Dmitriev V., Tsiomenko A., Roshkova Z., Tuneva D. Investigations of mannan and glucan in the cell wall of Candida boidinii cultivated on methanol. Antonie van Leeuwenhoek. 65:1994;13-20.
11. Goulding K.H. Aerobic microbial growth on one-carbon substrates. Trevan M.D., Boffey S., Goulding K.H., Standury S. Biotechnology: The Biological Principles-1987. 1987;22-42 Tata McGraw-Hill, New Delhi.
12. Kato N., Sahm H., Wagner F. Steady-state kinetics of formaldehyde dehydrogenase and fornate dehydrogenase from a methanol-utilizing yeast, Candida boidinii. Biochim. Biophys. Acta. 566:1979;12-20.
13. Labrou N., Clonis Y. The interaction of Candida boidinii formate dehydrogenase with a new family of chimeric biomimetic dye-ligands. Arch. Biochem. Biophysics. 10:1995;169-178.
14. Labrou N., Karagouni A., Clonis Y. Biomimetic-dye affinity absorbents for enzyme purification: Application to the one-step purification of Candida boidinii formate dehydrogenase. Biotechnol. Bioeng. 48:1995;278-288.
15. Lee J., Komagata K. Taxonomic study of methanol-assimilating yeasts. Gen. Appl. Microbiol. 26:1980;133-158.
16. Pilat P., Prokop A. The effect of methanol, formaldehyde and formic acid on growth of Candida boidinii 11 Bh. Biotechnol. Bioeng. 14:1975;1717-1728.
17. Reuss M., Sahm H., Wagner H. Mikrobielle protein-gewinnung auf methanol basis. Chem.-Ing. Technik. 46:1974;669-672.
18. Roggenkamp R., Sahm H., Hinkelmann W., Wagner F. Alcohol oxidase and catalase in peroxisomes of methanol-grown Candida boidinii. Eur. J. Biochem. 59:1975;231-236.
19. Sahm H., Wagner F. Microbial assimilation of methanol. Eur. J. Biochem. 36:1973;250-256.
20. Sahm H. Metabolism of methanol by yeasts. Ghose T.K., Fiechter A., Blakebrough N. Advances in Biochemical Engineering - 1977. 1977;77-103 Springer, Berlin.
21. Schütte H., Flossdorf J., Sahm H., Kula M.-R. Purification and properties of formaldehude dehydrgenase and formate dehydrogenase from Candida boidinii. Eur. J. Biochem. 62:1976;151-160.
22. Takors R., Wiechrt W., Weuster-Botz D. Experimental design for the identification of macrokinetic modelsand model discrimination. Biotechnol. Bioeng. 56:1997;564-576.
23. van Dijken J.P., Otto R., Harder W. Growth of Hansenula polymorpha in a methanol-limited chemostat. Arch. Microbiol. 111:1976;137-144.
24. Volfova O., Pilat P. Studies on methanol-oxidizing yeasts. I. Isolation and growth studies. Folia Microbiol. 19:1975;249-256.
25. Volfova O. Studies on methanol-oxidizing yeast. III Enzyme. Folia Microbiol. 20:1975;307-319.
26. Volfova O., Zizka Z., Anderova M. Effect of increasing methanol concentrations on physiology and cytology of Candida boidinii. Folia Microbiol. 37:1992;413-420.
27. Wedy M., 1992. Thesis, RWTH Aachen, FRG (from Takors et al., 1997).
28. Weuster-Botz D., Paschold H., Striegek B., Gieren H., Kula M.-R., Wandrey C. Continuous computer controlled production of formate dehydrogenase (FDH) and isolation on a pilot scale. Chem. Eng. Technol. 17:1994;131-137.
29. Weuster-Botz D., Wandrey C. Medium optimization by genetic algorithm for continuous production of formate dehydrogrnase. Process Biochem. 30:1995;563-571.