Gene transfer mediated by fusion protein hemagglutinin reconstituted in cationic lipid vesicles

Gene Therapy

Volumn 6, Issue 5, 1999, Pages 823-832

  Schoen, P ^a   Chonn, A ^b,c   Cullis, P R ^b,c   Wilschut, J ^a   Scherrer, P ^b,c  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b Inex Pharmaceuticals   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Carrier system; Gene therapy; Hemagglutinin; Intracellular delivery; Non viral gene delivery; Virosomes

Indexed keywords

HYBRID PROTEIN; VIRUS HEMAGGLUTININ;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL STRAIN BHK; ERYTHROCYTE GHOST; GENE TARGETING; GENE TRANSFER; GENETIC TRANSFECTION; LIPID VESICLE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CELLS, CULTURED; CRICETINAE; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HEMAGGLUTININS, VIRAL; LIPOSOMES; ORTHOMYXOVIRIDAE; QUATERNARY AMMONIUM COMPOUNDS; VIRAL FUSION PROTEINS;

ANIMALIA; INFLUENZA VIRUS;

EID: 0033011921     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300919     Document Type: Article

References (37)

1. Cristiano RJ, Roth JA. Molecular conjugates: a targeted gene delivery vector for molecular medicine. J Mol Med 1995; 73: 479-486.
2. Gao X, Huang L. Cationic liposome-mediated gene transfer. Gene Therapy 1995; 2: 710-722.
3. Remy JS et al. Targeted gene transfer into hepatoma cells with lipopolyamine-condensed DNA particles presenting galactose ligands: a stage toward artificial viruses. Proc Natl Acad Sci USA 1995; 92: 1744-1748.
4. Cooper MJ. Noninfectious gene transfer and expression systems for cancer gene therapy. Semin Oncol 1996; 23: 172-187.
5. Felgner PL et al. Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc Natl Acad Sci USA 1987; 84: 7413-7417.
6. Zhou X, Huang L. DNA transfection mediated by cationic liposomes containing lipopolylysine: characterization and mechanism of action. Biochim Biophys Acta 1994; 1189: 195-203.
7. Wrobel I, Collins D. Fusion of cationic liposomes with mammalian cells occurs after endocytosis. Biochim Biophys Acta 1995; 1235: 296-304.
8. Friend DS, Papahadjopoulos D, Debs RJ. Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes. Biochim Biophys Acta 1996; 1278: 41-50.
9. Wagner E, Curiel D, Cotten M. Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis. Adv Drug Del Rev 1994; 14: 113-135.
10. Gottschalk S et al. A novel DNA-peptide complex for efficient gene transfer and expression in mammalian cells. Gene Therapy 1996; 3: 448-457.
11. Wagner E et al. Influenza virus hemagglutinin HA-2 N-terminal fusigenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle. Proc Natl Acad Sci USA 1992; 89: 7934-7938.
12. Kamata H, Yagisawa H, Takahashi S, Hirata H. Amphiphilic peptides enhance the efficiency of liposome-mediated DNA transfection. Nucl Acids Res 1994; 22: 536-537.
13. Plank C et al. The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems. J Biol Chem 1994; 269: 12918-12924.
14. Wilschut J, Bron R. The influenza virus hemagglutinin: membrane fusion activity in intact virons and reconstituted virosomes. In: Bentz J (ed). Viral Fusion Mechanisms. CRC Press: Boca Raton, FL, 1993, pp 133-160.
15. Stegmann T. Membrane fusion. Curr Biol 1994; 4: 551-554.
16. Hughson FM. Molecular mechanisms of protein-mediated membrane fusion. Curr Opin Struct Biol 1995; 5: 507-513.
17. Stegmann T et al. Functional reconstitution of influenza virus envelopes. EMBO J 1987; 6: 2651-2659.
18. Bron R et al. Preparation, properties, and applications of reconstituted influenza virus envelopes (virosomes). Meth Enzymol 1993; 220: 313-331.
19. Schoen P, Bron R, Wilschut J. Delivery of foreign substances to cells mediated by fusion-active reconstituted influenza virus envelopes. J Liposome Res 1993; 3: 767-792.
20. Bron R, Ortiz A, Wilschut J. Cellular cytoplasmic delivery of a polypeptide toxin by reconstituted influenza virus envelopes (virosomes). Biochemistry 1994; 33: 9110-9117.
21. Stegmann T et al. Evaluation of viral membrane fusion assays. Comparison of the octadecylrhodamine dequenching assay with the pyrene excimer assay. Biochemistry 1993; 32: 11330-11337.
22. Ohkuma S, Poole B. Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents. Proc Natl Acad Sci USA 1978; 75: 3327-3331.
23. Stegmann T, Hoekstra D, Scherphof G, Wilschut J. Fusion activity of influenza virus. A comparison between biological and artificial target membrane vesicles. J Biol Chem 1986; 261: 10966-10969.
24. Gershon H, Ghirlando R, Guttman SB, Minsky A. Mode of formation and structural features of DNA-cationic liposome complexes used for transfection. Biochemistry 1993; 32: 7143-7151.
25. Xu Y, Szoka Jr FC. Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. Biochemistry 1996; 35: 5616-5623.
26. Farhood H, Serbina N, Huang L. The role of dioleoylphosphatidylethanolamine in cationic liposome mediated gene transfer. Biochim Biophys Acta 1995; 1235: 289-295.
27. Litzinger DC et al. Fate of cationic liposomes and their complex with oligonucleotide in vivo. Biochim Biophys Acta 1996; 1281: 139-149.
28. Liu F, Yang J, Huang L, Liu D. New cationic lipid formulations for gene transfer. Pharm Res 1996; 13: 1856-1860.
29. Hagstrom JE et al. Complexes of non-cationic liposomes and histone H1 mediate efficient transfection of DNA without encapsulation. Biochim Biophys Acta 1996; 1284: 47-55.
30. Zabner J et al. Cellular and molecular barriers to gene transfer by a cationic lipid. J Biol Chem 1995; 270: 18997-19007.
31. Shangguan T, Alford D, Bentz J. Influenza-virus-liposome lipid mixing is leaky and largely insensitive to the material properties of the target membrane. Biochemistry 1996; 35: 4956-4965.
32. Saeki Y et al. Development and characterization of cationic liposomes conjugated with HVJ (Sendai virus): reciprocal effect of cationic lipid for in vitro and in vivo gene transfer. Hum Gene Ther 1997; 8: 2133-2144.
33. Birnboim HC, Doly J. A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Res 1979; 7: 1513-1523.
34. Ames BN. Assay of inorganic phosphate, total phosphate and phosphatases. Meth Enzymol 1966; 8: 115-118.
35. Böttcher CJF, van Gent CM, Pries CA. Rapid and sensitive submicro phosphorus determination. Anal Chim Acta 1961; 24: 203-204.
36. Steck TL, Kant JA. Preparation of impermeable ghosts and inside-out vesicles from human erythrocyte membranes. Meth Enzymol 1974; 31: 172-180.
37. Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Biochem Physiol 1959; 37: 911-917.