Protection from lethal coxsackievirus-induced pancreatitis by expression of gamma interferon

Journal of Virology

Volumn 73, Issue 3, 1999, Pages 1756-1766

  Horwitz, Marc S ^a   Krahl, Troy ^a   Fine, Cody ^a   Lee, Jae ^a   Sarvetnick, Nora ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGUANIDINE; GAMMA INTERFERON; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; COXSACKIE VIRUS; COXSACKIE VIRUS INFECTION; DEATH; FEMALE; HYPOGLYCEMIA; KNOCKOUT MOUSE; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREATITIS; PRIORITY JOURNAL; PROTECTION; TRANSGENIC MOUSE; VIRUS REPLICATION;

EID: 0033011863     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.3.1756-1766.1999     Document Type: Article

References (32)

1. Chapman, N. M., A. I. Ramsingh, and S. Tracy. 1997. Genetics of Coxsackievirus virulence. Curr. Top. Microbiol. Immunol. 223:227-258.
2. Chatterjee, N., J. Hou, P. Dockstader, and T. Charbonneau. 1992. Coxsackievirus B4 infection alters thymic, splenic, and peripheral lymphocyte repertoire preceding onset of hyperglycemia in mice. J. Med. Virol. 38:124-131.
3. Chelbi-Alix, M. K., F. Quignon, L. Pelicano, M. H. M. Koken, and H. de Thé. 1998. Resistance to virus infection conferred by the interferon-induced promyelocytic leukemia protein. J. Virol. 72:1043-1051.
4. Clements, G., D. Galbraith, and K. Taylor. 1995. Coxsackie B virus infection and onset of childhood diabetes. Lancet 346:221-223.
5. Coccia, E. M., G. Romeo, A. Nissim, and G. Marziali. 1990. A full-length 2-5A synthetase cDNA transfected in NIH-3T3 cells impairs EMCV but not VSV replication. Virology 179:228-233.
6. Corbett, J. A., R. G. Tilton, K. Chang, K. S. Hasan, Y. Ido, J. L. Wang, M. A. Sweetland, J. R. Lancaster, Jr., J. R. Williamson, and M. L. McDaniel. 1992. Aminoguanidine inhibits nitric oxide formation and prevents diabetic vascular dysfunction. Diabetes 41:552-556.
7. Dalton, D. K., S. Pitts-Meek, S. Keshav, I. S. Figari, A. Bradley, and T. A. Stewart. 1993. Multiple defects of immune cell function in mice with disrupted interferon-gamma genes. Science 259:1739-1742.
8. Geiger, K., E. Howes, M. Gallina, X. J. Huang, G. H. Travis, and N. Sarvetnick. 1994. Transgenic mice expressing IFN-γ in the retina develop inflammation and photoreceptor loss. Investig. Ophthalmol. Vis. Sci. 35:2667-2681.
9. Geiger, K., E. L. Howes, and N. Sarvetnick. 1994. Ectopic expression of gamma interferon in the eye protects transgenic mice from intraocular herpes simplex virus type 1 infections. J. Virol. 68:5556-5567.
10. Geiger, K. D., T. Nash, S. Sawyer, T. Krahl, G. Patstone, J. C. Reed, S. Krajewski, D. Dalton, M. J. Buchmeier, and N. Sarvetnick. 1997. Interferon-γ protects against herpes simplex virus type 1-mediated neuronal death. Virology 238:189-197.
11. Gu, D.-L., M.-S. Lee, T. Krahl, and N. Sarvetnick. 1994. Transitional cells in the regenerating pancreas. Development 120:1873-1881.
12. Gu, D.-L., and N. Sarvetnick. 1993. Epithelial cell proliferation and islet neogenesis in IFN-γ transgenic mice. Development 118:33-46.
13. Guidotti, L. G., T. Ishikawa, M. V. Hobbs, B. Malzke, R. Shreiber, and F. V. Chisari. 1996. Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes. Immunity 4:25-36.
14. Hartig, P., G. Madge, and S. Webb. 1983. Diversity within a human isolate of coxsackie B4: relationship to viral-induced diabetes. J. Med. Virol. 11:23-30.
15. + T lymphocytes in coxsackievirus B3-induced myocarditis. J. Virol. 69:6720-6728.
16. Horwitz, M. S., C. F. Evans, D. B. McGaver, M. Rodriguez, and M. B. A. Oldstone. 1997. Primary demyelination in transgenic mice expressing interferon-gamma. Nat. Med. 3:1037-1041.
17. Kagi, D., and H. Hengartner. 1996. Different roles for cytotoxic T cells in the control of infections with cytopathic versus noncytopathic viruses. Curr. Opin. Immunol. 8:472-477.
18. Lowenstein, C. J., S. L. Hill, A. Lafond-Walker, J. Wu, G. Allen, M. Landavere, N. R. Rose, and A. Herskowitz. 1996. Nitric oxide inhibits viral replication in murine myocarditis. J. Clin. Investig. 97:1837-1843.
19. Meurs, E., Y. Watanabe, S. Kadereit, G. Barber, M. Katze, K. Chong, B. Williams, and A. Hovanessian. 1992. Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eukaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth. J. Virol. 66:5805-5814.
20. Pavlovic, J., T. Zürcher, O. Haller, and P. Staeheli. 1990. Resistance to influenza virus and vesicular stomatitis virus conferred by expression of human MxA protein. J. Virol. 64:3370-3375.
21. Ramsay, A. J., J. Ruby, and I. A. Ramshaw. 1993. A case for cytokines as effector molecules in the resolution of virus infection. Immunol. Today 14:155-157.
22. Ramsingh, A. I., W. T. Lee, D. N. Collins, and L. E. Armstrong. 1997. Differential recruitment of B and T cells in coxsackievirus B4-induced pancreatitis is influenced by a capsid protein. J. Virol. 71:8690-8697.
23. Samuel, C. E. 1991. Antiviral-regulated cellular proteins and their surprisingly selective antiviral activities. Virology 183:1-11.
24. Sarvetnick, N., D. Liggitt, S. Pitts, S. Hansen, and T. Stewart. 1988. Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gamma. Cell 52:773-782.
25. Sarvetnick, N., J. Shizuru, D. Liggitt, L. Martin, B. McIntyre, A. Gregory, T. Parslow, and T. Stewart. 1990. Loss of pancreatic islet tolerance induced by beta-cell expression of interferon-gamma. Nature 346:844-847.
26. Sen, G. C., and R. M. Ransohoff. 1993. Interferon-induced antiviral actions and their regulation. Adv. Virus Res. 42:57-102.
27. Simpson, E. M., C. C. Linder, E. E. Sargent, M. T. Davisson, L. E. Mobraaten, and J. J. Sharp. 1997. Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice. Nat. Genet. 16:19-27.
28. Spitalny, G. L., and E. A. Havell. 1984. Monoclonal antibody to murine gamma interferon inhibits lymphokine-induced antiviral and macrophage tumoricidal activities. J. Exp. Med. 158:1560-1565.
29. Staeheli, P., F. Pitossi, and J. Pavlovic. 1993. Mx proteins: GTPases with antiviral activity. Trends Cell Biol. 3:268-272.
30. Tracy, S., N. M. Chapman, J. Romeru, and A. I. Ramsingh. 1996. Genetics of coxsackievirus B cardiovirulence and inflammatory heart muscle disease. Trends Microbiol. 4:175-179.
31. Webb, S., R. Loria, G. Madge, and S. Kibrick. 1976. Susceptibility of mice to group B coxsackie virus is influenced by the diabetic gene. J. Exp. Med. 143:1239-1248.
32. Yoon, J., M. Austin, T. Onodera, and A. Notkins. 1979. Isolation of a virus from the pancreas of a child with diabetic ketoacidosis. N. Engl. J. Med. 300:1173-1179.