PEEP-induced pulmonary vasoconstriction in neonatal piglets: Analysis by pressure-flow curves

Pediatric Pulmonology

Volumn 28, Issue 1, 1999, Pages 12-17

  Venkataraman, Shekhar T ^a,b   Allen, Jeffrey W ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b NONE   (United States)

Author keywords

Ca2+ channel; Lung stretch; Neonate; PEEP; Piglet; Pressure flow relationship; Pulmonary artery; Pulmonary vascular resistance

Indexed keywords

VERAPAMIL;

AIRFLOW; AIRWAY PRESSURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; LUNG ARTERY PRESSURE; LUNG HEMODYNAMICS; LUNG VASCULAR RESISTANCE; LUNG VASOCONSTRICTION; NEWBORN; NONHUMAN; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; SWINE;

ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; DISEASE MODELS, ANIMAL; HEMODYNAMIC PROCESSES; LINEAR MODELS; POSITIVE-PRESSURE RESPIRATION; PRESSURE; PULMONARY ARTERY; PULMONARY WEDGE PRESSURE; REFERENCE VALUES; SENSITIVITY AND SPECIFICITY; SWINE; VASCULAR RESISTANCE; VASOCONSTRICTION;

EID: 0033011149     PISSN: 87556863     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-0496(199907)28:1<12::AID-PPUL3>3.0.CO;2-X     Document Type: Article

References (29)

1. Lopez-Muniz R, Stephens NL, Bromberger-Barnea B, Permutt S, Riley RL. Critical closure of pulmonary vessels analyzed in terms of Starling resistor model. J Appl Physiol 1968;24:625-635.
2. West JB, Dollery CT, Naimark A. Distribution of blood flow in isolated lung: relation to vascular and alveolar pressure. J Appl Physiol 1964;19:713-724.
3. Fuhrman BP, Smith-Wright DL, Venkataraman ST, Howland DF. Pulmonary vascular resistance after cessation of positive end-expiratory pressure. J Appl Physiol 1989;66:660-668.
4. Rankin JS, Olsen LO, Arentzen CE, Tyson GS, Maier G, Smith PK, Harminon JW Jr, McHale PA, Anderson RW, Sabiston DC. The effects of airway pressure on cardiac function in intact dogs and man. Circulation 1982;66:108-120.
5. Venkataraman ST, Fuhrman BP, Howland DF, DeFrancisis M. Positive end-expiratory pressure-induced, calcium-channel mediated increases in pulmonary vascular resistance in neonatal lambs. Crit Care Med 1993;21:1066-1076.
6. Graham R, Skoog C, Oppenheimer L, Rabson J, Goldberg HS. Critical closure in the canine pulmonary vasculature. Circ Res 1982;50:566-572.
7. Shoukas AA. Pressure-flow and pressure-volume relations in the entire pulmonary vascular bed of the dog determined by two-port analysis. Circ Res 1975;37:809-818.
8. DeBono EF, Caro CG. Effect of lung-inflating pressure on pulmonary blood pressure and flow. Am J Physiol 1963;205:1178-1186.
9. Permutt S, Bromberger-Barnea B, Bane HN. Alveolar pressure, pulmonary venous pressure and vascular waterfall. Med Thorac 1962;19:239-260.
10. Mitzner W, Sylvester JT. Hypoxic vasoconstriction and fluid filtration in pig lungs. J Appl Physiol 1981;51:1065-1071.
11. Dawson CA, Grimm DJ, Linehan JH. Effects of lung inflation on longitudinal distribution of pulmonary vascular resistance. J Appl Physiol 1977;43:1089-1092.
12. Nieman GF, Paskanik AS, Bredenberg CE. Effect of positive end-expiratory pressure on alveolar capillary perfusion. J Thorac Cardiovasc Surg 1988;95:712-716.
13. Fuhrman BP, Everitt J, Lock JE. Cardiopulmonary effects of unilateral airway pressure changes in intact infant lambs. J Appl Physiol 1984;56:1439-1448.
14. Fuhrman BP, Smith-Wright DL, Kulik TJ, Lock JE. Effects of static and fluctuatuing airway pressure on intact pulmonary circulation. J Appl Physiol 1986;60:114-122.
15. Ducas J, Duval D, Dasilva H, Boiteau P, Prewitt RM. Treatment of canine pulmonary hypertension: effects of norepinephrine and isoproterenol on pulmonary vascular pressure-flow characteristics. Circulation 1987;75:235-242.
16. Graham R, Skoog C, Macedo W, Carter J, Oppenheimer L, Rabson J, Goldberg HS. Dopamine, dobutamine and phentolamine effects of pulmonary vascular mechanics. J Appl Physiol 1983; 54:1277-1283.
17. Lodato RF, Michael JR, Murray PA. Multipoint pulmonary vascular pressure-cardiac output plots in conscious dogs. Am J Physiol 1985;249:351-357.
18. Domino KB, Pinsky MR. Effect of positive end-expiratory pressure on hypoxic pulmonary vasoconstriction in the dog. Am J Physiol 1990;259:697-705.
19. Hakim TS, Malik AB. Hypoxic vasoconstriction in blood and plasma perfused lungs. Respir Physiol 1988;72:109-122.
20. Lejeune P, Deloof T, Leeman M, Melot C, Naeije R. Multipoint pulmonary vascular pressure/flow relationships in hypoxic and in normoxic dogs: effects of nitrous oxide with and without cyclooxygenase inhibition. Anesthesiology 1988;68:92-99.
21. D'Orio V, Fatemi M, Mendes P, Saad G, Marcelle R. Effect of positive end-expiratory pressure on pulmonary vascular pressure-flow characteristics in canine endotoxin shock. Circ Shock 1992; 37:189-197.
22. Fuhrman BP, Smith-Wright DL, Venkataraman S, Orr RA, Howland DF. Proximal mean airway pressure: a good estimator of mean alveolar pressure during continuous positive-pressure breathing. Crit Care Med 1989;17:666-670.
23. Albert RK, Lamm WJE, Rickaby DA, Al-Tinawi A, Dawson CA. Lung inflation distends small arteries (<1 mm) in excised dog lungs. J Appl Physiol 1993;75:2595-2601.
24. Howell JBL, Permutt S, Proctor DF, Riley RL. Effect of inflation of the lung on different parts of the pulmonary vascular bed. J Appl Physiol 1961;16:71-76.
25. Nelin LD, Krenz GS, Rickaby DA, Linehan JA, Dawson CA. A distensible vessel model applied to hypoxic pulmonary vasoconstriction in the neonatal pig. J Appl Physiol 1993;74:2049-2056.
26. Kulik TJ, Evans JN, Gamble WJ. Stretch-induced contraction in pulmonary arteries. Am J Physiol 1988;255:1391-1398.
27. Levin DL, Rudolph AM, Heymann MA, Phibbs RH. Morphological development of the pulmonary vascular bed in fetal lambs. Circulation 1976;53:144-151.
28. Katz JA, Ozanne GM, Zinn SE, Fairley HB. Time course and mechanisms of lung-volume increase with PEEP in acute pulmonary failure. Anesthesiology 1981;54:9-16.
29. Pick MJ, Hatch DJ, Kerr AA. The effect of positive end-expiratory pressure on lung mechanics and arterial oxygenation after open heart surgery in young children. Br J Anaesth 1976; 48:983-987.