메뉴 건너뛰기




Volumn 11, Issue 7, 1999, Pages 2291-2304

Acute application of NGF increases the firing rate of aged rat basal forebrain neurons

Author keywords

Acetylcholine; Alzheimer's disease; Medial septum; Neurodegeneration; Neurotrophins

Indexed keywords

ANTIBODY; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR; TRANSFERRIN RECEPTOR;

EID: 0033009979     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.1999.00644.x     Document Type: Article
Times cited : (30)

References (106)
  • 3
    • 0026010125 scopus 로고
    • Involvement of nerve growth factor and its receptor in the regulation of the cholinergic function in aged rats.
    • Alberch, J., Perez‐Navarro, E., Arenas, E., Marsal, J. 1991 Involvement of nerve growth factor and its receptor in the regulation of the cholinergic function in aged rats. J. Neurochem., 57, 1483 1487.
    • (1991) J. Neurochem. , vol.57 , pp. 1483-1487
    • Alberch, J.1    Perez‐Navarro, E.2    Arenas, E.3    Marsal, J.4
  • 6
    • 0345557871 scopus 로고    scopus 로고
    • Carrier mediated delivery of NGF: alterations in basal forebrain neurons in aged rats revealed using antibodies against low and high affinity NGF receptors.
    • Bäckman, C., Rose, G.M., Bartus, R.T., Hoffer, B.J., Mufson, E.J., Granholm, A.‐Ch. E. 1997 Carrier mediated delivery of NGF: alterations in basal forebrain neurons in aged rats revealed using antibodies against low and high affinity NGF receptors. J. Comp. Neurol., 387, 1 11.
    • (1997) J. Comp. Neurol. , vol.387 , pp. 1-11
    • Bäckman, C.1    Rose, G.M.2    Bartus, R.T.3    Hoffer, B.J.4    Mufson, E.J.5    Granholm, A.‐Ch. E.6
  • 7
    • 0029843679 scopus 로고    scopus 로고
    • Systemic administration of a nerve growth factor conjugate reverses age‐related cognitive dysfunction and prevents cholinergic neuron atrophy.
    • Bäckman, C., Rose, G.M., Hoffer, B.J., Henry, M.A., Bartus, R.T., Friden, P.M., Granholm, A.‐Ch. E. 1996a Systemic administration of a nerve growth factor conjugate reverses age‐related cognitive dysfunction and prevents cholinergic neuron atrophy. J. Neurosci., 16, 5437 5442.
    • (1996) J. Neurosci. , vol.16 , pp. 5437-5442
    • Bäckman, C.1    Rose, G.M.2    Hoffer, B.J.3    Henry, M.A.4    Bartus, R.T.5    Friden, P.M.6    Granholm, A.‐Ch. E.7
  • 8
    • 0019972810 scopus 로고
    • The cholinergic hypothesis of geriatric memory dysfunction.
    • Bartus, R.T., Dean, R.L., Beer, B., Lippa, A.S. 1982 The cholinergic hypothesis of geriatric memory dysfunction. Science, 217, 408 417.
    • (1982) Science , vol.217 , pp. 408-417
    • Bartus, R.T.1    Dean, R.L.2    Beer, B.3    Lippa, A.S.4
  • 9
    • 0027526580 scopus 로고
    • HSV‐1 vector‐mediated gene transfer of the human nerve growth factor receptor p75hNGFR defines high affinity NGF binding.
    • Battleman, D.S., Geller, A.I., Chao, M.V. 1993 HSV‐1 vector‐mediated gene transfer of the human nerve growth factor receptor p75hNGFR defines high affinity NGF binding. J. Neurosci., 13, 941 951.
    • (1993) J. Neurosci. , vol.13 , pp. 941-951
    • Battleman, D.S.1    Geller, A.I.2    Chao, M.V.3
  • 12
    • 0028079865 scopus 로고
    • In vivo demonstration of subcellular localization of anti‐transferrin receptor monoclonal antibody‐colloidal gold conjugate in brain capillary endothelium.
    • Bickel, U., Kang, Y.S., Yoshikawa, T., Pardridge, W.M. 1994 In vivo demonstration of subcellular localization of anti‐transferrin receptor monoclonal antibody‐colloidal gold conjugate in brain capillary endothelium. J. Histochem. Cytochem., 42, 1493 1497.
    • (1994) J. Histochem. Cytochem. , vol.42 , pp. 1493-1497
    • Bickel, U.1    Kang, Y.S.2    Yoshikawa, T.3    Pardridge, W.M.4
  • 13
    • 0029074694 scopus 로고
    • Characterization of nerve growth factor (NGF) release from hippocampal neurons: evidence for a constitutive and an unconventional sodium‐dependent regulated pathway.
    • Blöchl, A. & Thoenen, H. 1995 Characterization of nerve growth factor (NGF) release from hippocampal neurons: evidence for a constitutive and an unconventional sodium‐dependent regulated pathway. Eur. J. Neurosci., 7, 1220 1228.
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 1220-1228
    • Blöchl, A.1    Thoenen, H.2
  • 14
    • 0030985884 scopus 로고    scopus 로고
    • Intracellular recordings from medial septal neurons during hippocampal theta rhythm.
    • Brazhnik, E.S. & Fox, S.E. 1997 Intracellular recordings from medial septal neurons during hippocampal theta rhythm. Exp. Brain Res., 114, 442 453.
    • (1997) Exp. Brain Res. , vol.114 , pp. 442-453
    • Brazhnik, E.S.1    Fox, S.E.2
  • 15
    • 0022447887 scopus 로고
    • Control of the neuronal rhythmic bursts in the septal pacemaker of theta‐rhythm: effects of anaesthetic and anticholinergic drugs.
    • Brazhnik, E.S. & Vinogradova, O.S. 1986 Control of the neuronal rhythmic bursts in the septal pacemaker of theta‐rhythm: effects of anaesthetic and anticholinergic drugs. Brain Res., 380, 94 106.
    • (1986) Brain Res. , vol.380 , pp. 94-106
    • Brazhnik, E.S.1    Vinogradova, O.S.2
  • 16
    • 0030297155 scopus 로고    scopus 로고
    • Transcytosis of protein through the mammalian cerebral epithelium and endothelium. III. Receptor‐mediated transcytosis through the blood–brain barrier of blood‐borne transferrin and antibody against the transferrin receptor.
    • Broadwell, R.D., Baker‐Cairns, B.J., Friden, P.M., Oliver, C., Villegas, J.C. 1996 Transcytosis of protein through the mammalian cerebral epithelium and endothelium. III. Receptor‐mediated transcytosis through the blood–brain barrier of blood‐borne transferrin and antibody against the transferrin receptor. Exp. Neurol., 142, 47 65.
    • (1996) Exp. Neurol. , vol.142 , pp. 47-65
    • Broadwell, R.D.1    Baker‐Cairns, B.J.2    Friden, P.M.3    Oliver, C.4    Villegas, J.C.5
  • 17
    • 0030458462 scopus 로고    scopus 로고
    • How structural features influence the biomembrane permeability of peptides.
    • Burton, P.S., Conradi, R.A., Ho, N.F., Hilgers, A.R., Borchardt, R.T. 1996 How structural features influence the biomembrane permeability of peptides. J. Pharm. Sci., 85, 1336 1340.
    • (1996) J. Pharm. Sci. , vol.85 , pp. 1336-1340
    • Burton, P.S.1    Conradi, R.A.2    Ho, N.F.3    Hilgers, A.R.4    Borchardt, R.T.5
  • 19
    • 0028074493 scopus 로고
    • Constitutive upregulation of calcium channel currents in rat phaeochromocytoma cells: role of c‐fos and c‐jun.
    • Cavalie, A., Berninger, B., Haas, C.A., Garcia, D.E., Lindholm, D., Lux, H.D. 1994 Constitutive upregulation of calcium channel currents in rat phaeochromocytoma cells: role of c‐fos and c‐jun. J. Physiol., 479, 11 27.
    • (1994) J. Physiol. , vol.479 , pp. 11-27
    • Cavalie, A.1    Berninger, B.2    Haas, C.A.3    Garcia, D.E.4    Lindholm, D.5    Lux, H.D.6
  • 20
    • 0026730310 scopus 로고
    • Neurotrophin receptors: a window into neuronal differentiation.
    • Chao, M.V. 1992 Neurotrophin receptors: a window into neuronal differentiation. Neuron, 9, 583 593.
    • (1992) Neuron , vol.9 , pp. 583-593
    • Chao, M.V.1
  • 21
    • 0030605874 scopus 로고    scopus 로고
    • Atrophy of cholinergic basal forebrain neurons following excitotoxic cortical lesions is reversed by intravenous administration of an NGF conjugate.
    • Charles, V., Mufson, E.J., Friden, P.M., Bartus, R.T., Kordower, J.H. 1996 Atrophy of cholinergic basal forebrain neurons following excitotoxic cortical lesions is reversed by intravenous administration of an NGF conjugate. Brain Res., 728, 193 203.
    • (1996) Brain Res. , vol.728 , pp. 193-203
    • Charles, V.1    Mufson, E.J.2    Friden, P.M.3    Bartus, R.T.4    Kordower, J.H.5
  • 22
    • 0028171962 scopus 로고
    • Reduced transport of (125I) nerve growth factor by cholinergic neurons and down‐regulated TrkA expression in the medial septum of aged rats.
    • Cooper, J.D., Lindholm, D., Sofroniew, M.V. 1994 Reduced transport of (125I) nerve growth factor by cholinergic neurons and down‐regulated TrkA expression in the medial septum of aged rats. Neuroscience, 62, 625 629.
    • (1994) Neuroscience , vol.62 , pp. 625-629
    • Cooper, J.D.1    Lindholm, D.2    Sofroniew, M.V.3
  • 23
    • 0025950097 scopus 로고
    • Hippocampal NGF levels are not reduced in the aged Fischer 344 rat.
    • Crutcher, K.A. & Weingartner, J. 1991 Hippocampal NGF levels are not reduced in the aged Fischer 344 rat. Neurobiol. Aging, 12, 449 454.
    • (1991) Neurobiol. Aging , vol.12 , pp. 449-454
    • Crutcher, K.A.1    Weingartner, J.2
  • 25
    • 0000241799 scopus 로고
    • pH and the recycling of transferrin during receptor‐mediated endocytosis.
    • Dautry‐Varsat, A., Ciechanover, A., Lodish, H.F. 1983 pH and the recycling of transferrin during receptor‐mediated endocytosis. Proc. Natl Acad. Sci. USA, 80, 2258 2262.
    • (1983) Proc. Natl Acad. Sci. USA , vol.80 , pp. 2258-2262
    • Dautry‐Varsat, A.1    Ciechanover, A.2    Lodish, H.F.3
  • 26
    • 0026602935 scopus 로고
    • Delayed treatment with nerve growth factor improves acquisition of a spatial task in rats with lesions of the nucleus basalis magnocellularis: evaluation of the involvement of different neurotransmitter systems.
    • Dekker, A.J., Gage, F.H., Thal, L.J. 1992 Delayed treatment with nerve growth factor improves acquisition of a spatial task in rats with lesions of the nucleus basalis magnocellularis: evaluation of the involvement of different neurotransmitter systems. Neuroscience, 48, 111 119.
    • (1992) Neuroscience , vol.48 , pp. 111-119
    • Dekker, A.J.1    Gage, F.H.2    Thal, L.J.3
  • 27
    • 0031214428 scopus 로고    scopus 로고
    • Nerve growth factor attenuates cholinergic deficits following traumatic brain injury in rats.
    • Dixon, C.E., Flinn, P., Bao, J., Venya, R., Hayes, R.L. 1997 Nerve growth factor attenuates cholinergic deficits following traumatic brain injury in rats. Exp. Neurol., 146 (2), 479 490.
    • (1997) Exp. Neurol. , vol.146 , Issue.2 , pp. 479-490
    • Dixon, C.E.1    Flinn, P.2    Bao, J.3    Venya, R.4    Hayes, R.L.5
  • 30
    • 0025938955 scopus 로고
    • NGF improves spatial memory in aged rodents as a function of age.
    • Fischer, W., Bjorklund, A., Chen, K., Gage, F.H. 1991 NGF improves spatial memory in aged rodents as a function of age. J. Neurosci., 11, 1889 1906.
    • (1991) J. Neurosci. , vol.11 , pp. 1889-1906
    • Fischer, W.1    Bjorklund, A.2    Chen, K.3    Gage, F.H.4
  • 31
    • 0026567917 scopus 로고
    • Progressive decline in spatial learning and integrity of forebrain cholinergic neurons in rats during aging.
    • Fischer, W., Chen, K., Gage, F.H., Bjorklund, A. 1992 Progressive decline in spatial learning and integrity of forebrain cholinergic neurons in rats during aging. Neurobiol. Aging, 13, 9 23.
    • (1992) Neurobiol. Aging , vol.13 , pp. 9-23
    • Fischer, W.1    Chen, K.2    Gage, F.H.3    Bjorklund, A.4
  • 32
    • 0024346318 scopus 로고
    • Degenerative changes in forebrain cholinergic nuclei correlate with cognitive impairments in aged rats.
    • Fischer, W., Gage, F.H., Bjorklund, A. 1989 Degenerative changes in forebrain cholinergic nuclei correlate with cognitive impairments in aged rats. Eur. J. Neurosci., 1, 34 45.
    • (1989) Eur. J. Neurosci. , vol.1 , pp. 34-45
    • Fischer, W.1    Gage, F.H.2    Bjorklund, A.3
  • 33
    • 0028064960 scopus 로고
    • Reversal of spatial memory impairments in aged rats by nerve growth factor and neurotrophins 3 and 4/5 but not by brain‐derived neurotrophic factor.
    • Fischer, W., Sirevaag, A., Wiegand, S.J., Lindsay, R.M., Bjorklund, A. 1994 Reversal of spatial memory impairments in aged rats by nerve growth factor and neurotrophins 3 and 4/5 but not by brain‐derived neurotrophic factor. Proc. Natl Acad. Sci. USA, 1991, 8607 8611.
    • (1994) Proc. Natl Acad. Sci. USA , vol.1991 , pp. 8607-8611
    • Fischer, W.1    Sirevaag, A.2    Wiegand, S.J.3    Lindsay, R.M.4    Bjorklund, A.5
  • 34
    • 0023643241 scopus 로고
    • Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor.
    • Fischer, W., Wictorin, K., Björklund, A., Williams, L.R., Varin, S., Gage, F.H. 1987 Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor. Nature, 329, 65 68.
    • (1987) Nature , vol.329 , pp. 65-68
    • Fischer, W.1    Wictorin, K.2    Björklund, A.3    Williams, L.R.4    Varin, S.5    Gage, F.H.6
  • 35
    • 0028136182 scopus 로고
    • Receptor‐mediated transport of therapeutics across the blood–brain barrier.
    • Friden, P.M. 1994 Receptor‐mediated transport of therapeutics across the blood–brain barrier. Neurosurgery, 35, 294 298.
    • (1994) Neurosurgery , vol.35 , pp. 294-298
    • Friden, P.M.1
  • 36
    • 0030438707 scopus 로고    scopus 로고
    • Characterization, receptor mapping and blood–brain barrier transcytosis of antibodies ot the human transferrin receptor.
    • Friden, P.M., Olson, T.S., Obar, R., Walus, L.R., Putney, S.D. 1996 Characterization, receptor mapping and blood–brain barrier transcytosis of antibodies ot the human transferrin receptor. J. Pharm. Exp. Ther., 278, 1491 1498.
    • (1996) J. Pharm. Exp. Ther. , vol.278 , pp. 1491-1498
    • Friden, P.M.1    Olson, T.S.2    Obar, R.3    Walus, L.R.4    Putney, S.D.5
  • 37
  • 40
    • 0023627477 scopus 로고
    • Characterization of the techniques of pressure ejection and microiontophoresis using in vivo electrochemistry.
    • Gerhardt, G.A. & Palmer, M.R. 1987 Characterization of the techniques of pressure ejection and microiontophoresis using in vivo electrochemistry. J. Neurosci. Meth., 22, 147 159.
    • (1987) J. Neurosci. Meth. , vol.22 , pp. 147-159
    • Gerhardt, G.A.1    Palmer, M.R.2
  • 41
    • 85013563873 scopus 로고
    • Hippocampal transplants in oculo: a model for establishment of isolated circuits. , in: Methods in Neurosciences
    • Granholm, A.‐Ch. E. 1991 Hippocampal transplants in oculo: a model for establishment of isolated circuits. In Cohn, M, ed. Methods in Neurosciences, Vol. 7. Academic Press, San Diego, pp. 327 345.
    • (1991) , vol.7 , pp. 327-345
    • Granholm, A.‐Ch. E.1
  • 44
    • 0029865021 scopus 로고    scopus 로고
    • Development of an intact blood–brain barrier in brain tissue transplants is dependent on the site of transplantation.
    • Granholm, A.‐Ch. E., Curtis, M., Diamond, D.M., Branch, B.J., Heman, K.L., Rose, G.M. 1996 Development of an intact blood–brain barrier in brain tissue transplants is dependent on the site of transplantation. Cell Transplantation, 5, 305 314.
    • (1996) Cell Transplantation , vol.5 , pp. 305-314
    • Granholm, A.‐Ch. E.1    Curtis, M.2    Diamond, D.M.3    Branch, B.J.4    Heman, K.L.5    Rose, G.M.6
  • 45
    • 0022979156 scopus 로고
    • Electrophysiology of AChE‐positive neurons in basal forebrain slices.
    • Griffith, W.H. & Matthews, R.T. 1986 Electrophysiology of AChE‐positive neurons in basal forebrain slices. Neurosci. Lett., 71, 169 174.
    • (1986) Neurosci. Lett. , vol.71 , pp. 169-174
    • Griffith, W.H.1    Matthews, R.T.2
  • 47
    • 0020666935 scopus 로고
    • Is Alzheimer’s disease caused by a lack of nerve growth factor?
    • Hefti, F. 1983 Is Alzheimer’s disease caused by a lack of nerve growth factor? Ann. Neurol., 13, 109 110.
    • (1983) Ann. Neurol. , vol.13 , pp. 109-110
    • Hefti, F.1
  • 48
    • 0022486717 scopus 로고
    • Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections.
    • Hefti, F. 1986 Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections. J. Neurosci., 6, 2155 2162.
    • (1986) J. Neurosci. , vol.6 , pp. 2155-2162
    • Hefti, F.1
  • 49
    • 0027972153 scopus 로고
    • Neurotrophic factor therapy for nervous system degenerative diseases.
    • Hefti, F. 1994 Neurotrophic factor therapy for nervous system degenerative diseases. J. Neurobiol., 25, 1418 1435.
    • (1994) J. Neurobiol. , vol.25 , pp. 1418-1435
    • Hefti, F.1
  • 50
    • 0024709111 scopus 로고
    • Nerve growth factor (NGF) induction of NGF receptor gene expression and cholinergic neuronal hypertrophy within the basal forebrain of the adult rat.
    • Higgins, G.A., Koh, S., Chen, K.S., Gage, F.H. 1989 Nerve growth factor (NGF) induction of NGF receptor gene expression and cholinergic neuronal hypertrophy within the basal forebrain of the adult rat. Neuron, 3, 247 256.
    • (1989) Neuron , vol.3 , pp. 247-256
    • Higgins, G.A.1    Koh, S.2    Chen, K.S.3    Gage, F.H.4
  • 51
    • 0031972834 scopus 로고    scopus 로고
    • Growth factor receptor tyrosine kinases acutely regulate neuronal sodium channels through the src signaling pathway.
    • Hilborn, M.D., Vaillancourt, R.R., Rane, S.G. 1998 Growth factor receptor tyrosine kinases acutely regulate neuronal sodium channels through the src signaling pathway. J. Neurosci., 18, 590 600.
    • (1998) J. Neurosci. , vol.18 , pp. 590-600
    • Hilborn, M.D.1    Vaillancourt, R.R.2    Rane, S.G.3
  • 52
    • 0000211808 scopus 로고
    • Unit 2.1, in: Assays for Antibody Production. Current Protocols in
    • Hornbeck, P. 1991 Unit 2.1. In: Coligan, J.E, ed. Assays for Antibody Production. Current Protocols in Immunology, Vol. 1. John Wiley. NY, pp. 1 2.
    • (1991) , vol.1 , pp. 1-2
    • Hornbeck, P.1
  • 54
    • 0028115022 scopus 로고
    • Neurotrophin signal transduction by the trk A receptor.
    • Kaplan, D.R. & Stephens, R.M. 1994 Neurotrophin signal transduction by the trk A receptor. J. Neurobiol., 25, 1404 1417.
    • (1994) J. Neurobiol. , vol.25 , pp. 1404-1417
    • Kaplan, D.R.1    Stephens, R.M.2
  • 55
    • 0028266334 scopus 로고
    • Positive feedback between acetylcholine and the neurotrophins nerve growth factor and brain‐derived neurotrophic factor in the rat hippocampus.
    • Knipper, M., Berzaghi, M., Blöchl, A., Breer, H., Theonen, H., Lindholm, D. 1993 Positive feedback between acetylcholine and the neurotrophins nerve growth factor and brain‐derived neurotrophic factor in the rat hippocampus. Eur. J. Neurosci., 6, 668 671.
    • (1993) Eur. J. Neurosci. , vol.6 , pp. 668-671
    • Knipper, M.1    Berzaghi, M.2    Blöchl, A.3    Breer, H.4    Theonen, H.5    Lindholm, D.6
  • 56
    • 0030867019 scopus 로고    scopus 로고
    • A new twist in an old story: the role for crosstalk of neuronal and trophic activity.
    • Knipper, M. & Rylett, R.J. 1997 A new twist in an old story: the role for crosstalk of neuronal and trophic activity. Neurochem. Int., 31, 659 676.
    • (1997) Neurochem. Int. , vol.31 , pp. 659-676
    • Knipper, M.1    Rylett, R.J.2
  • 57
    • 0024464226 scopus 로고
    • Loss of NGF receptor immunoreactivity in basal forebrain neurons of aged rats: correlation with spatial memory impairment.
    • Koh, S., Chang, P., Collier, T.J., Loy, R. 1989 Loss of NGF receptor immunoreactivity in basal forebrain neurons of aged rats: correlation with spatial memory impairment. Brain Res., 498, 31 997 31  404.
    • (1989) Brain Res. , vol.498 , pp. 31 997-31
    • Koh, S.1    Chang, P.2    Collier, T.J.3    Loy, R.4
  • 59
    • 0028558577 scopus 로고
    • Intravenous administration of a transferrin receptor antibody‐nerve growth factor conjugate prevents the degeneration of cholinergic striatal neurons in a model of Huntington disease.
    • Kordower, J.H., Charles, V., Bayer, R., Bartus, R.T., Putney, S., Walus, L.R., Friden, P.M. 1994 Intravenous administration of a transferrin receptor antibody‐nerve growth factor conjugate prevents the degeneration of cholinergic striatal neurons in a model of Huntington disease. Neurobiol., 91, 9077 9080.
    • (1994) Neurobiol. , vol.91 , pp. 9077-9080
    • Kordower, J.H.1    Charles, V.2    Bayer, R.3    Bartus, R.T.4    Putney, S.5    Walus, L.R.6    Friden, P.M.7
  • 61
    • 0023067115 scopus 로고
    • Nerve growth factor treatment after brain injury prevents neuronal death.
    • Kromer, L.F. 1987 Nerve growth factor treatment after brain injury prevents neuronal death. Science, 235, 214 216.
    • (1987) Science , vol.235 , pp. 214-216
    • Kromer, L.F.1
  • 62
    • 0024372793 scopus 로고
    • Septo‐hippocampal neurons in the aged rat: relation between their electrophysiological and pharmacological properties and behavioral performances.
    • Lamour, Y., Bassant, M.H., Jobert, A., Joly, M. 1989 Septo‐hippocampal neurons in the aged rat: relation between their electrophysiological and pharmacological properties and behavioral performances. Neuorbiol. Aging, 10, 181 186.
    • (1989) Neuorbiol. Aging , vol.10 , pp. 181-186
    • Lamour, Y.1    Bassant, M.H.2    Jobert, A.3    Joly, M.4
  • 63
    • 0023202663 scopus 로고
    • Septo‐hippocampal neurons: altered properties in the aged rat.
    • Lamour, Y., Dutar, P., Jobert, A. 1987 Septo‐hippocampal neurons: altered properties in the aged rat. Brain Res., 416, 277 282.
    • (1987) Brain Res. , vol.416 , pp. 277-282
    • Lamour, Y.1    Dutar, P.2    Jobert, A.3
  • 64
    • 0024274070 scopus 로고
    • Developmental appearance of nerve growth factor in the rat brain: significant deficits in the aged forebrain.
    • Lärksfors, L., Ebendal, T., Whittemore, S.R., Persson, H., Hoffer, B., Olson, L. 1988 Developmental appearance of nerve growth factor in the rat brain: significant deficits in the aged forebrain. Prog. Brain Res., 78, 27 31.
    • (1988) Prog. Brain Res. , vol.78 , pp. 27-31
    • Lärksfors, L.1    Ebendal, T.2    Whittemore, S.R.3    Persson, H.4    Hoffer, B.5    Olson, L.6
  • 65
    • 85120514976 scopus 로고
    • Lee, M.G., Chrobak, J.J., Sik, A.,. Wiley, R.G., Buzsaki, G. 1994 Hippocampal theta activity following selective lesion of the septal cholinergic system. Neuroscience, 62, 1033 1047.
    • (1994) , pp. 1033-1047
    • Lee, M.G.1    Chrobak, J.J.2    Sik, A.3    . Wiley, R.G.4    Buzsaki, G.5
  • 66
    • 0028816634 scopus 로고
    • Regulation of voltage‐gated ion channels by NGF and ciliary neurotrophic factor in SK‐N‐SH neuroblastoma cells.
    • Lesser, S.S. & Lo, D. 1995 Regulation of voltage‐gated ion channels by NGF and ciliary neurotrophic factor in SK‐N‐SH neuroblastoma cells. J. Neurosci., 15, 253 261.
    • (1995) J. Neurosci. , vol.15 , pp. 253-261
    • Lesser, S.S.1    Lo, D.2
  • 67
    • 0027184399 scopus 로고
    • Nerve growth factor and nociception.
    • Lewin, G.R. & Mendell, L.M. 1993 Nerve growth factor and nociception. Trends Neurosci., 16, 353 359.
    • (1993) Trends Neurosci. , vol.16 , pp. 353-359
    • Lewin, G.R.1    Mendell, L.M.2
  • 68
    • 0022387610 scopus 로고
    • Conformational changes in muscarinic receptors may produce diminished cholinergic neurotransmission and memory in aged rats.
    • Lippa, A.S., Loullis, C.C., Rotrosen, J., Cordasco, D.M., Critchett, D.J., Joesph, J.A. 1985 Conformational changes in muscarinic receptors may produce diminished cholinergic neurotransmission and memory in aged rats. Neurobiol. Aging, 6, 317 323.
    • (1985) Neurobiol. Aging , vol.6 , pp. 317-323
    • Lippa, A.S.1    Loullis, C.C.2    Rotrosen, J.3    Cordasco, D.M.4    Critchett, D.J.5    Joesph, J.A.6
  • 70
    • 0025042157 scopus 로고
    • Regional changes in NGF receptor immuohistochemical labeling in the septum of the aged rat.
    • Markram, H. & Segal, M. 1990 Regional changes in NGF receptor immuohistochemical labeling in the septum of the aged rat. Neurobiol. Aging, 11, 481 484.
    • (1990) Neurobiol. Aging , vol.11 , pp. 481-484
    • Markram, H.1    Segal, M.2
  • 71
    • 0029902122 scopus 로고    scopus 로고
    • Long‐term functional recovery from age‐induced spatial memory impairments by nerve growth factor gene transfer to the rat basal forebrain.
    • Martinez‐Serrano, A., Fischer, W., Soderstrom, S., Ebendal, T., Bjorklund, A. 1996 Long‐term functional recovery from age‐induced spatial memory impairments by nerve growth factor gene transfer to the rat basal forebrain. Proc. Natl Acad. Sci. USA, 93 (13), 6355 6360.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , Issue.13 , pp. 6355-6360
    • Martinez‐Serrano, A.1    Fischer, W.2    Soderstrom, S.3    Ebendal, T.4    Bjorklund, A.5
  • 72
    • 0025822049 scopus 로고
    • A comparison of extracellular and intracellular recordings from medial septum/diagonal band neurons in vitro.
    • Matthews, R.T. & Lee, W.L. 1991 A comparison of extracellular and intracellular recordings from medial septum/diagonal band neurons in vitro. Neuroscience, 42, 451 462.
    • (1991) Neuroscience , vol.42 , pp. 451-462
    • Matthews, R.T.1    Lee, W.L.2
  • 73
    • 0026378521 scopus 로고
    • Exogenous nerve growth factor reverses age‐related structural changes in neocortical neurons in the aging rat.
    • Mervis, R.F., Pope, D., Lewis, R., Dvorak, R.M., Williams, L.R. 1991 Exogenous nerve growth factor reverses age‐related structural changes in neocortical neurons in the aging rat. Ann. NY Acad. Sci., 640, 95 101.
    • (1991) Ann. NY Acad. Sci. , vol.640 , pp. 95-101
    • Mervis, R.F.1    Pope, D.2    Lewis, R.3    Dvorak, R.M.4    Williams, L.R.5
  • 74
    • 0021741295 scopus 로고
    • Effects of aging on rat cortical presynaptic cholinergic processes.
    • Meyer, E.M., St. Onge, E., Crews, F.T. 1984 Effects of aging on rat cortical presynaptic cholinergic processes. Neurobiol. Aging, 5, 315 317.
    • (1984) Neurobiol. Aging , vol.5 , pp. 315-317
    • Meyer, E.M.1    St. Onge, E.2    Crews, F.T.3
  • 75
    • 0024401637 scopus 로고
    • Nerve growth factor in Alzheimer’s disease: to treat or not to treat?
    • Mobley, W.C. 1989 Nerve growth factor in Alzheimer’s disease: to treat or not to treat? Neurobiol. Aging, 10, 578 580.
    • (1989) Neurobiol. Aging , vol.10 , pp. 578-580
    • Mobley, W.C.1
  • 76
    • 0029613880 scopus 로고
    • Nerve growth factor facilitates cholinergic neurotransmission between nucleus basalis and the amygdala in rat: an electrophysiological analysis.
    • Moises, H.C., Womble, M.D., Washburn, M.S., Williams, L.R. 1995 Nerve growth factor facilitates cholinergic neurotransmission between nucleus basalis and the amygdala in rat: an electrophysiological analysis. J. Neurosci., 15, 8131 8142.
    • (1995) J. Neurosci. , vol.15 , pp. 8131-8142
    • Moises, H.C.1    Womble, M.D.2    Washburn, M.S.3    Williams, L.R.4
  • 77
    • 0029798860 scopus 로고    scopus 로고
    • Differential regulation of hippocampal neurotrophins during aging in rats.
    • Narisawa‐Saito, M. & Nawa, H. 1996 Differential regulation of hippocampal neurotrophins during aging in rats. J. Neurochem., 67, 1124 1131.
    • (1996) J. Neurochem. , vol.67 , pp. 1124-1131
    • Narisawa‐Saito, M.1    Nawa, H.2
  • 78
    • 0025840262 scopus 로고
    • Age‐ and sex‐related differences in the nerve growth factor distribution in the rat brain.
    • Nishizuka, M., Katoh‐Semba, R., Eto, K., Yasumasa, A., Iizuka, R., Kato, K. 1991 Age‐ and sex‐related differences in the nerve growth factor distribution in the rat brain. Brain Res. Bull., 27, 685 688.
    • (1991) Brain Res. Bull. , vol.27 , pp. 685-688
    • Nishizuka, M.1    Katoh‐Semba, R.2    Eto, K.3    Yasumasa, A.4    Iizuka, R.5    Kato, K.6
  • 79
    • 0027135449 scopus 로고
    • Oral administration of idebenone, a stimulator of NGF synthesis, recovers reduced NGF content in aged rat brain.
    • Nitta, A., Hasegawa, T., Nabeshima, T. 1993 Oral administration of idebenone, a stimulator of NGF synthesis, recovers reduced NGF content in aged rat brain. Neuroscience Lett., 163, 219 222.
    • (1993) Neuroscience Lett. , vol.163 , pp. 219-222
    • Nitta, A.1    Hasegawa, T.2    Nabeshima, T.3
  • 81
    • 0027175943 scopus 로고
    • Nerve growth factor‐induced excitation of selected neurons in the brain which is blocked by a low‐affinity receptor antibody.
    • Palmer, M.A., Eriksdotter‐Nilsson, M., Henschen, A., Ebendal, T., Olson, L. 1993 Nerve growth factor‐induced excitation of selected neurons in the brain which is blocked by a low‐affinity receptor antibody. Exp. Brain Res., 93, 226 230.
    • (1993) Exp. Brain Res. , vol.93 , pp. 226-230
    • Palmer, M.A.1    Eriksdotter‐Nilsson, M.2    Henschen, A.3    Ebendal, T.4    Olson, L.5
  • 82
    • 0024267852 scopus 로고
    • Antagonism of ethanol on cerebellar purkinje neurons by the benzodiazepine inverse agonists Ro15–4513 and FG 7142: Electrophysiological studies.
    • Palmer, M.A., Van Horne, C.G., Harlan, J.T., Moore, E.A. 1988 Antagonism of ethanol on cerebellar purkinje neurons by the benzodiazepine inverse agonists Ro15–4513 and FG 7142: Electrophysiological studies. J. Pharm. Exp. Ther., 247, 1018 1024.
    • (1988) J. Pharm. Exp. Ther. , vol.247 , pp. 1018-1024
    • Palmer, M.A.1    Van Horne, C.G.2    Harlan, J.T.3    Moore, E.A.4
  • 83
    • 0025836586 scopus 로고
    • Selective transport of an antitransferrin receptor antibody through the blood–brain barrier in vivo.
    • Pardridge, W.M., Buciak, J.L., Friden, P.M. 1991 Selective transport of an antitransferrin receptor antibody through the blood–brain barrier in vivo. J. Pharm. Exp. Ther., 259, 66 70.
    • (1991) J. Pharm. Exp. Ther. , vol.259 , pp. 66-70
    • Pardridge, W.M.1    Buciak, J.L.2    Friden, P.M.3
  • 84
    • 0028279458 scopus 로고
    • Transport of human recombinant brain‐derived neurotrophic factor (BDNF) through the rat blood–brain barrier in vivo using vector‐mediated peptide drug delivery.
    • Pardridge, W.M., Kang, Y.S., Buciak, J.L. 1994 Transport of human recombinant brain‐derived neurotrophic factor (BDNF) through the rat blood–brain barrier in vivo using vector‐mediated peptide drug delivery. Pharm. Res., 11, 738 746.
    • (1994) Pharm. Res. , vol.11 , pp. 738-746
    • Pardridge, W.M.1    Kang, Y.S.2    Buciak, J.L.3
  • 85
    • 0003717437 scopus 로고
    • The Rat Brain in Stereotaxic Coordinates
    • Paxinos, G. & Watson, C. 1986 The Rat Brain in Stereotaxic Coordinates. 2nd edn. Academic Press, San Diego.
    • (1986)
    • Paxinos, G.1    Watson, C.2
  • 86
    • 0030475453 scopus 로고    scopus 로고
    • The effects of intrahippocampal BDNF and NGF on spatial learning in aged Long Evans rats.
    • Pelleymounter, M.A., Cullen, M.J., Baker, M.B., Gollub, M., Wellman, C. 1996 The effects of intrahippocampal BDNF and NGF on spatial learning in aged Long Evans rats. Mol. Chem. Neuropath., 29, 211 226.
    • (1996) Mol. Chem. Neuropath. , vol.29 , pp. 211-226
    • Pelleymounter, M.A.1    Cullen, M.J.2    Baker, M.B.3    Gollub, M.4    Wellman, C.5
  • 87
    • 0029928170 scopus 로고    scopus 로고
    • Permeability at the blood–brain barrier and blood–nerve barriers of the neurotrophic factors: NGF, CNTF, NT‐3, BDNF.
    • Podulso, J.F. & Curran, G.L. 1996 Permeability at the blood–brain barrier and blood–nerve barriers of the neurotrophic factors: NGF, CNTF, NT‐3, BDNF. Mol. Brain Res., 36, 280 286.
    • (1996) Mol. Brain Res. , vol.36 , pp. 280-286
    • Podulso, J.F.1    Curran, G.L.2
  • 88
    • 0027178807 scopus 로고
    • Acetylcholine synthesis and release following continuous intracerebral administration of NGF in adult and aged Fischer 344 rats.
    • Rylett, R.J., Goddard, S., Schmidt, B.M., Williams, L.R. 1993 Acetylcholine synthesis and release following continuous intracerebral administration of NGF in adult and aged Fischer 344 rats. J. Neurosci., 13, 3956 3963.
    • (1993) J. Neurosci. , vol.13 , pp. 3956-3963
    • Rylett, R.J.1    Goddard, S.2    Schmidt, B.M.3    Williams, L.R.4
  • 89
    • 0028019154 scopus 로고
    • Role of neurotrophins in cholinergic‐neurone function in the adult and aged CNS.
    • Rylett, R.J. & Williams, L.R. 1994 Role of neurotrophins in cholinergic‐neurone function in the adult and aged CNS. Trends Neurosci., 17, 486 491.
    • (1994) Trends Neurosci. , vol.17 , pp. 486-491
    • Rylett, R.J.1    Williams, L.R.2
  • 90
    • 0028589458 scopus 로고
    • Nerve growth factor and Alzheimer’s disease.
    • Scott, S.A. & Crutcher, K.A. 1994 Nerve growth factor and Alzheimer’s disease. Rev. Neurosci., 5, 179 211.
    • (1994) Rev. Neurosci. , vol.5 , pp. 179-211
    • Scott, S.A.1    Crutcher, K.A.2
  • 91
    • 0029022112 scopus 로고
    • Nerve growth factor in Alzheimer’s disease: increased levels throughout the brain coupled with declines in nucleus basalis.
    • Scott, S.A., Mufson, E.J., Weingartner, J.A., Skau, K.A., Crutcher, K.A. 1995 Nerve growth factor in Alzheimer’s disease: increased levels throughout the brain coupled with declines in nucleus basalis. J. Neurosci., 15, 6213 6221.
    • (1995) J. Neurosci. , vol.15 , pp. 6213-6221
    • Scott, S.A.1    Mufson, E.J.2    Weingartner, J.A.3    Skau, K.A.4    Crutcher, K.A.5
  • 92
    • 0029925683 scopus 로고    scopus 로고
    • Intracellular signaling pathways activated by neurotrophic factors.
    • Segal, R. & Greenberg, M. 1996 Intracellular signaling pathways activated by neurotrophic factors. Annu. Rev. Neurosci., 19, 463 489.
    • (1996) Annu. Rev. Neurosci. , vol.19 , pp. 463-489
    • Segal, R.1    Greenberg, M.2
  • 93
    • 0030861966 scopus 로고    scopus 로고
    • Rapid retrograde tyrosine phosphorylation of trkA and other proteins in rat sympathetic neurons in compartmented cultures.
    • Senger, D.L. & Campenot, R. 1997 Rapid retrograde tyrosine phosphorylation of trkA and other proteins in rat sympathetic neurons in compartmented cultures. J.Cell Biol., 138, 411 421.
    • (1997) J.Cell Biol. , vol.138 , pp. 411-421
    • Senger, D.L.1    Campenot, R.2
  • 94
    • 0029893741 scopus 로고    scopus 로고
    • Aged‐related decrease in cholinergic synaptic transmission in three hippocampal subfields.
    • Shen, J. & Barnes, C.A. 1996 Aged‐related decrease in cholinergic synaptic transmission in three hippocampal subfields. Neurobiol. Aging, 17, 439 451.
    • (1996) Neurobiol. Aging , vol.17 , pp. 439-451
    • Shen, J.1    Barnes, C.A.2
  • 95
    • 0027938821 scopus 로고
    • TrkA‐immunoreactive profiles in the central nervous system: colocalization with neurons containing p75 nerve growth factor receptor, choline acetyltransferase, and serotonin.
    • Sobreviela, T., Clary, D.O., Reichardt, L.F., Brandabur, M.M., Kordower, J.H., Mufson, E.J. 1994 TrkA‐immunoreactive profiles in the central nervous system: colocalization with neurons containing p75 nerve growth factor receptor, choline acetyltransferase, and serotonin. J. Comp. Neurol., 350, 587 611.
    • (1994) J. Comp. Neurol. , vol.350 , pp. 587-611
    • Sobreviela, T.1    Clary, D.O.2    Reichardt, L.F.3    Brandabur, M.M.4    Kordower, J.H.5    Mufson, E.J.6
  • 96
    • 0028090546 scopus 로고
    • Nerve growth factor treatment induces high‐potassium evoked calcium dependent acetylcholine release in cultured embryonic rat septal cells.
    • Suzuki, T., Kanagawa, M., Takada, Y., Fujimoto, K., Kawashima, K. 1994 Nerve growth factor treatment induces high‐potassium evoked calcium dependent acetylcholine release in cultured embryonic rat septal cells. Brain Res., 665, 311 314.
    • (1994) Brain Res. , vol.665 , pp. 311-314
    • Suzuki, T.1    Kanagawa, M.2    Takada, Y.3    Fujimoto, K.4    Kawashima, K.5
  • 97
    • 0030744442 scopus 로고    scopus 로고
    • Nerve growth factor, central nervous system apoptosis and adrenocortical activity in aged Fischer‐344/brown Norway F1 hybrid rats.
    • Taglialatelia, G., Robinson Gegg, R., Perez‐Polo, J.R. 1997 Nerve growth factor, central nervous system apoptosis and adrenocortical activity in aged Fischer‐344/brown Norway F1 hybrid rats. Brain Res. Bull., 43, 229 233.
    • (1997) Brain Res. Bull. , vol.43 , pp. 229-233
    • Taglialatelia, G.1    Robinson Gegg, R.2    Perez‐Polo, J.R.3
  • 98
    • 0027282065 scopus 로고
    • Age‐related decline in cholinergic synaptic transmission in hippocampus.
    • Taylor, L. & Griffith, W.H. 1993 Age‐related decline in cholinergic synaptic transmission in hippocampus. Neurobiol. Aging, 14, 509 515.
    • (1993) Neurobiol. Aging , vol.14 , pp. 509-515
    • Taylor, L.1    Griffith, W.H.2
  • 99
    • 0028947293 scopus 로고
    • A single pulse of nerve growth factor triggers long‐term neuronal excitability through sodium channel gene induction.
    • Toledo‐Aral, J.J., Brehm, P., Halegoua, S., Mandel, G. 1995 A single pulse of nerve growth factor triggers long‐term neuronal excitability through sodium channel gene induction. Neuron, 14, 607 611.
    • (1995) Neuron , vol.14 , pp. 607-611
    • Toledo‐Aral, J.J.1    Brehm, P.2    Halegoua, S.3    Mandel, G.4
  • 100
    • 0025513602 scopus 로고
    • Nerve growth factor infusion in the primate brain reduces lesion‐induced cholinergic neuronal degeneration.
    • Tuszynski, M.H., Amaral, D.G., Gage, F.H. 1990 Nerve growth factor infusion in the primate brain reduces lesion‐induced cholinergic neuronal degeneration. J. Neurosci., 10, 3604 3614.
    • (1990) J. Neurosci. , vol.10 , pp. 3604-3614
    • Tuszynski, M.H.1    Amaral, D.G.2    Gage, F.H.3
  • 102
    • 0029613811 scopus 로고
    • The pharmacotherapy of Alzheimer’s disease based on the cholinergic hypothesis: an update.
    • Weinstock, M. 1995 The pharmacotherapy of Alzheimer’s disease based on the cholinergic hypothesis: an update. Neurodegeneration, 4, 349 356.
    • (1995) Neurodegeneration , vol.4 , pp. 349-356
    • Weinstock, M.1
  • 103
    • 0026010866 scopus 로고
    • Exogenous nerve growth factor stimulates choline acetyltransferase activity in aging Fischer 344 male rats.
    • Williams, L.R. 1991 Exogenous nerve growth factor stimulates choline acetyltransferase activity in aging Fischer 344 male rats. Neurobiol. Aging, 12, 39 46.
    • (1991) Neurobiol. Aging , vol.12 , pp. 39-46
    • Williams, L.R.1
  • 104
    • 0025954742 scopus 로고
    • Exogenous NGF affects cholinergic transmitter function and Y‐maze behavior in aged Fischer 344 male rats.
    • Williams, L.R., Rylett, R.J., Moises, H.C., Tang, A.H. 1991 Exogenous NGF affects cholinergic transmitter function and Y‐maze behavior in aged Fischer 344 male rats. Can. J. Neurol. Sci., 18 (3 Suppl.), 403 407.
    • (1991) Can. J. Neurol. Sci. , vol.18 , Issue.3 Suppl. , pp. 403-407
    • Williams, L.R.1    Rylett, R.J.2    Moises, H.C.3    Tang, A.H.4
  • 106
    • 0030248402 scopus 로고    scopus 로고
    • Nerve growth factor and the neurotrophic factor hypothesis.
    • Yuen, E.C., Howe, C.L., Holtzman, D.M., Mobley, W.C. 1996 Nerve growth factor and the neurotrophic factor hypothesis. Brain Dev., 18, 362 368.
    • (1996) Brain Dev. , vol.18 , pp. 362-368
    • Yuen, E.C.1    Howe, C.L.2    Holtzman, D.M.3    Mobley, W.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.