The versatility of polysorbate 80 (Tween 80) as an ionophore

Journal of Pharmaceutical Sciences

Volumn 88, Issue 2, 1999, Pages 258-260

  Thoman, Charles J ^a  

^a UNIVERSITY OF THE SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZOBENZENE DERIVATIVE; AZULENE; FERROCENE; GUANIDINE; IONOPHORE; PARAQUAT; POLYSORBATE 80;

ARTICLE; ARTIFICIAL MEMBRANE; DRUG TRANSPORT; ION TRANSPORT; LIPOPHILICITY; MEMBRANE TRANSPORT;

EID: 0033009903     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js980216n     Document Type: Article

References (18)

1. Thoman, C. J. The Ionophoric Properties of Polysorbate 80 (Tween 80). J. Pharm. Sci. 1986, 75, 983.
2. Thoman, C. J.; Habeeb, T. D.; Huhn, M.; Korpusik, M.; Slish, D. F. The Use of Polysorbate 80 (Tween 80) as a Phase Transfer Catalyst. J. Org. Chem. 1989, 54, 4476.
3. Thoman, C. J.; Vermeulen, L. A.; Coffee, A. M.; DeSanto, R. J. Effect of Dietary Polysorbate 80 on the Serum Concentrations of Calcium and Magnesium in the Rat. J. Agric. Food Chem. 1993, 41, 714.
4. Thoman, C. J. The Effect of Temperature on the Transport Capabilities of Some Common Ionophores. J. Am. Chem. Soc. 1985, 107, 1437. This work has recently been confirmed: Borowitz, G. B. et al. Metal Cation Transport Studies Comparing Dibenzo-18-Crown-6 (DB18C6) with N,N,N′,N′-Tetrakis(n-propyl)-2,3-naphthalenedioxydiacetamide (Npr). J. Inclusion Phenom. Mol. Recogit. Chem. 1998, 30, 271.
5. Thoman, C. J. The Effect of Temperature on the Transport Capabilities of Some Common Ionophores. J. Am. Chem. Soc. 1985, 107, 1437. This work has recently been confirmed: Borowitz, G. B. et al. Metal Cation Transport Studies Comparing Dibenzo-18-Crown-6 (DB18C6) with N,N,N′,N′-Tetrakis(n-propyl)-2,3-naphthalenedioxydiacetamide (Npr). J. Inclusion Phenom. Mol. Recogit. Chem. 1998, 30, 271.
6. Cheng, K. L., Ueno, K., Imamura, T., Eds. CRC Handbook of Organic Analytical Reagents; CRC Press: Boca Raton, FL, 1982; pp 231-238.
7. Perez-Ruiz, T.; Martinez-Lozano, C.; Tomas, V. Simultaneous Flow Injection Determination of Diquat and Paraquat in Foodstuffs, Natural Waters and Biological Fluids. Intern. J. Environ. Anal. Chem. 1991, 44, 243.
8. 60. A New, Inexpensive and Facile Methodol. J. Am. Chem. Soc. 1992, 114, 7917.
9. Allemand, P.-M. et al. Two Different Fullerenes Have the Same Cyclic Voltametry. J. Am. Chem. Soc. 1991, 113, 1050.
10. Chia, P. S. K. et al. Supramolecular Transport of Metal Ammine and Amine Complexes by the Natural Ionophore Lasalocid A. The Selective Enantiomeric Transport of Chiral Metal Complexes. J. Am. Chem. Soc. 1991, 113, 2533.
11. Lindoy, L. F.; Walker, G. W.; Everett, G. W. Supramolecular Transport of Metal Complexes. Chiroselective Membrane Transport of Metal Amine Complexes by a Polyether Ionophore, Lasalocid A. J. Am. Chem. Soc. 1990, 112, 3659.
12. Shinkai, S. et al. Hexasulfonated Calix[6]arene Derivatives: A New Class of Catalysts, Surfactants and Host Molecules. J. Am. Chem. Soc. 1986, 108, 2409.
13. Alam, I.; Gutsche, C. D. Calixerenes. 24. Complexation by Water-soluble Calixarenes. J. Org. Chem. 1990, 55, 4487.
14. Diederich, F. Molecular Recognition in Aqueous Solution. J. Chem. Educ. 1990, 67, 813.
15. Diederich, F.; Dick, K. A New Water Soluble Cyclophane Type Host-Guest Complexation with Aromatic Guests in Aqueous Solution and Acceleration of the Transport of Arenes Through an Aqueous Phase. J. Am. Chem. Soc. 1984, 106, 8024
16. Rethwisch, D. G.; Subramanian, A.; Yi, G.; Dordick, J. S. Enzyme Facilitated Transport of Organic Acids Through Liquid Membranes. J. Am. Chem. Soc. 1990, 112, 1649.
17. B. Manno: private communication..
18. + Complex in Water: A Molecular Dynamics Simulation. J. Am. Chem. Soc. 1990, 112, 5716.