A somatropin counterfeit challenging the European Pharmacopoeia monograph

Pharmacy and Pharmacology Communications

Volumn 5, Issue 1, 1999, Pages 61-66

  Charton, Emmanuelle ^a   Wierer, Michael ^b   Spieser, Jean Marc ^a   Van Dorsselaer, Alain ^c   Rautmann, Guy ^a  

^a European Network of National Information Centers   (France)

^b Landesinstitut Offentlichen G   (Germany)

^c Institut de Chimie   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN GROWTH HORMONE;

AMINO TERMINAL SEQUENCE; ANALYTIC METHOD; CONFERENCE PAPER; DRUG QUALITY; GEL PERMEATION CHROMATOGRAPHY; ISOELECTRIC FOCUSING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PEPTIDE MAPPING; POLYACRYLAMIDE GEL ELECTROPHORESIS; QUALITY CONTROL;

EID: 0033009856     PISSN: 14608081     EISSN: None     Source Type: Journal    
DOI: 10.1211/146080899128734082     Document Type: Conference Paper

References (6)

1. European Pharmacopoeia. 3rd ed. (1997) Somatropin for Injection 0952. Council of Europe, Strasbourg, pp1524-1526
2. Haro, L. S., Lewis, U. J., Garcia, M., Bustamante, J., Martinez, A. O., Ling, N. C. (1996) Glycosylated human growth-hormone - a novel 24kDa Hgh-N variant. Biochem. Biophys. Res. Commun. 228: 549-556
3. Kostyo, J. L., Skottner, A., Brostedt, P., Roos, P., Cameron, C. M., Forsman, A., Fryklund, L., Adamafio, N. A., Skoog, I. (1987) Biological characterization of purified native 20-kDa human growth-hormone. Biochim. Biophys. Acta 925: 314-324
4. Prusiner, S. P., Dearmond, S. J. (1995) Prion protein amyloid and neurodegeneration. Amyloid Int. J. Exp. Clin. Invest. 2: 39-65
5. Pharmeuropa Vol. 9.1 (1997a) Somatropin for Injection. Council of Europe, Strasbourg, pp 81-85
6. Pharmeuropa Vol 9.3 (1997b) Polyacrylamide gel electrophor0 esis. Council of Europe, Strasbourg, pp 528-534