Regional patterns of myocardial sympathetic denervation in dilated cardiomyopathy: An analysis using carbon-11 hydroxyephedrine and positron emission tomography

Heart

Volumn 81, Issue 3, 1999, Pages 262-270

  Hartmann, F ^a   Ziegler, S ^b   Nekolla, S ^b   Hadamitzky, M ^b   Seyfarth, M ^b   Richardt, G ^a   Schwaiger, M ^b  

^a UNIVERSITY OF LÜBECK   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

C 11 hydroxyephedrine; Dilated cardiomyopathy; Heart failure; Positron emission tomography; Sympathetic nervous system

Indexed keywords

3 HYDROXYEPHEDRINE; AMMONIA; CARBON 11; CATECHOLAMINE DERIVATIVE; EPHEDRINE DERIVATIVE; GERMANIUM; NITROGEN 13;

ADRENERGIC SYSTEM; ADULT; ARTICLE; AUTONOMIC DENERVATION; CARDIOMYOPATHY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; HEART DILATATION; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART SCINTISCANNING; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; ISOTOPE LABELING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROGNOSIS;

EID: 0033009377     PISSN: 13556037     EISSN: None     Source Type: Journal    
DOI: 10.1136/hrt.81.3.262     Document Type: Article

References (50)

1. Francis GS, Goldsmith SR, Levine TB, et al. The neurohumoral axis in congestive heart failure. Ann Intern Med 1984;101:370-7.
2. Leimbach WN, Wallin GB, Victor RG, et al. Direct evidence from intraneural recordings for increased central sympathetic outflow in patients with heart failure. Circulation 1986;73:913-19.
3. Francis GS, Rector TS, Cohn JN. Sequential neurohumoral measurements in patients with congestive heart failure. Am Heart J 1988;116:1464-8.
4. Swedberg K, Eneroth P, Kjekshus J, et al. Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality. Circulation 1990;82:1730-6.
5. Francis GS, Benedict C, Johnstone DE, et al. Comparison of neuroendocrine activation in patients with left ventricular dysfunction with and without congestive heart failure: a substudy of the studies of left ventricular dysfunction (SOLVD). Circulation 1990;82:1724-9.
6. Hasking GJ, Esler MD, Jennings GL, et al. Norepinephrine spillover to plasma in patients with congestive heart failure: evidence of increased overall and cardiorenal sympathetic nervous activity. Circulation 1986;73:615-21.
7. Fowler MB, Laser JA, Hopkins GL, et al. Assessement of the β-adrenergic receptor pathway in the intact failing human heart: progressive receptor down-regulation and subsensitivity to agonist response. Circulation 1986;74:1290-302.
8. Bristow MR, Ginsburg R, Umans V, et al. β1-and β2-adrenergic receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective β1-receptor down-regulation in heart failure. Circ Res 1986;59:297-309.
9. Brodde OE. β1- and β2-adrenoceptors in the human heart property, function, and alterations in chronic heart failure. Pharmacol Rev 1991;43:203-42.
10. Bristow MR, Hershberger RE, Port JD, et al. Beta-adrenergic pathways in nonfailing and failing human ventricular myocardium. Circulation 1990;82:12-25.
11. Bohm M, Gierschik P, Jakobs KH. Increase of Gi α in human hearts with dilated but not ischemic cardiomyopathy. Circulation 1990;82:1249.
12. Bristow MR, Feldman AM. Changes in the receptor-G protein-adenyl cyclase system in heart failure from various types of heart muscle disease. Basic Res Cardiol 1992;1:15-35.
13. Rose CP, Burgess JH, Cousineau D. Reduced aortocoronary sinus extraction of norepinephrine in patients with left ventricular failure secondary to long-standing pressure or volume overload. Circulation 1983;68:241-4.
14. Meredith IT, Eisenhofer G, Lambert GW, et al. Cardiac sympathetic nervous activity in congestive heart failure: evidence for increased neuronal norepinephrine release and preserved neuronal uptake. Circulation 1993;88:136-45.
15. Port JD, Gilbert EM, Larrabee P, et al. Neurotransmitter depletion compromises the ability of indirect-acting amines to provide inotropic support in the failing human heart. Circulation 1990;81:929-38.
16. Rose CP, Burgess JH, Cousineau D. Tracer norepinephrine kinetics in coronary circulation of patients with heart failure secondary to chronic pressure and volume overload. J Clin Invest 1985;76:1740-7.
17. Bohm M, La Rosée K, Schwinger RHG, et al. Evidence for reduction of norepinephrine uptake sites in the failing human heart. J Am Coll Cardiol 1995;25:146-53.
18. Schwaiger M, Kalff V, Rosenspire K, et al. Noninvasive evaluation of sympathetic nervous system in human heart by positron emission tomography. Circulation 1990;82:457-64.
19. Schwaiger M, Hutchins GD, Kalff V, et al. Evidence for regional catecholamine uptake and storage sites in the transplanted human heart by positron emission tomography. J Clin Invest 1991;87:1681-90.
20. Allman KC, Stevens MJ, Wieland DM, et al. Noninvasive assessment of cardiac diabetic neuropathy by carbon-11 hydroxyephedrine and positron emission tomography. J Am Coll Cardiol 1993;22:1425-32.
21. Schwaiger M, Guibourg H, Rosenspire K, et al. Effect of regional myocardial ischemia on sympathetic nervous system as assessed by fluorine-18-metaraminol. J Nucl Med 1990;31:1352-7.
22. Schömig A, Dart AM, Dietz R, et al. Release of endogenous catecholamines in the ischemic myocardium of the rat. Part A: locally mediated release. Circ Res 1984;55:689-701.
23. Schömig A, Fischer S, Kurz T, et al. Nonexocytotic release of endogenous noradrenaline in the ischemic and anoxic rat heart: mechanisms and metabolic requirements. Circ Res 1987;60:194-205.
24. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Heart rate variability: standards of measurement, physiological interpretation, and clinical use. Circulation 1996;93:1043-65.
25. Rosenspire KC, Haka MS, Van DM, et al. Synthesis and preliminary evaluation of carbon-11-metahydroxyephedrine: a false transmitter agent for heart neuronal imaging. J Nucl Med 1990;31:1328-34.
26. Melon P, Schwaiger M. Imaging of metabolism and autonomic innervation of the heart by positron emission tomography. Eur J Nucl Med 1992;19:453-64.
27. Allman KC, Wieland DM, Muzik O, et al. Carbon-II hydroxyephedrine with positron emission tomography for serial assessment of cardiac adrenergic neuronal function after acute myocardial infarction in humans. J Am Coll Cardiol 1993;22:368-75.
28. Calkins H, Allman K, Bolling S, et al. Correlation between scintigraphic evidence of regional sympathetic neuronal dysfunction and ventricular refractoriness in the human heart. Circulation 1993;88:172-9.
29. Melon PG, Nguyen N, DeGrado TR, et al. Imaging of cardiac neuronal function after cocaine exposure using carbon-11 hydroxyephedrine and positron emission tomography. J Am Coll Cardiol 1994;23:1693-9.
30. Wolpers H, Nguyen N, Rosenpire K, et al. C-11 hydroxyephedrine as a marker for neuronal catecholamine retention in reperfused canine myocardium. Coron Artery Dis 1991;2:923-9.
31. Rabinovitch MA, Rose CP, Rouleau JL, et al. Metaiodobenzylguanidine [131I] scintigraphy detects impaired myocardial sympathetic neuronal transport function of canine mechanical-overload heart failure. Circ Res 1987;61:797-804.
32. Schofer J, Spielmann R, Schuchert A, et al. Iodine-131-meta-iodobenzylguanidine scintigraphy: a noninvasive method to demonstrate myocardial adrenergic nervous system disintegrity in patients with idiopathic dilated cardiomyopathy. J Am Coll Cardiol 1988;12:1252-8.
33. Glowniak JV, Turner FE, Gray LL, et al. Iodine-123 metaiodobenzylguanidine imaging of the heart in idiopathic congestive cardiomyopathy and cardiac transplants. J Nucl Med 1989;30:1182-91.
34. DeGrado TR, Hutchins GD, Toorongian SA, et al. Myocardial kinetics of carbon-11-meta-hydroxyephedrine: retention mechanisms and effects of norepinephrine. J Nucl Med 1993;34:1287-93.
35. Kienzle MG, Ferguson DW, Birkett CL, et al. Clinical, hemodynamic and sympathetic neural correlates of heart rate variability in congestive heart failure. Am J Cardiol 1992;69:761-7.
36. Rundqvist B, Elam M, Bergmann-Sverrisdottir Y, et al. Increased cardiac adrenergic drive procedes generalized sympathetic activation in human heart failure. Circulation 1997;95:169-75.
37. Glowniak JV, Turner FE, Gray LL, et al. Iodine-123 metaiodobenzylguanidine imaging of the heart in idiopathic congestive cardiomyopathy and cardiac transplants. J Nucl Med 1989;30:1182-91.
38. Simmons WW, Freeman MR, Grima EA, et al. Abnormalities of cardiac sympathetic function in pacing-induced heart failure as assessed by (123-I) metaiodobenzylguanidine scintigraphy. Circulation 1994;89:2843-51.
39. Takatsu H, Uno Y, Fujiwara H. Modulation ofleft ventricular iodine-125-MIBG accumulation in cardiomyopathic syrian hamsters using the renin-angiotensin system. J Nucl Med 1995;36:1055-61.
40. Glowniak JV. Cardiac studies with metaiodobenzylguanidine: a critique of methods and interpretation of results. J Nucl Med 1995;36:2133-7.
41. Merlet P, Valette H, Dubois RJ, et al. Prognostic value of cardiac metaiodobenzylguanidine imaging in patients with heart failure. J Nucl Med 1992;33:471-7.
42. Goldman S, Johnson G, Cohn JN, et al. Mechanism of death in heart failure: the vasodilator-heart failure trials. The V-HeFT VA cooperative studies group. Circulation 1093; 87(suppl 4):24-31.
43. Levine TB, Francis GS, Goldsmith SR, et al. Activity of the sympathetic nervous system and renin-angiotensin system assessed by plasma hormone levels and their relationship to hemodynamic abnormalities in congestive heart failure. Am J Cardiol 1982;49:1659-66.
44. Cohn JN, Levine TB, Olivari MT, et al. Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure. N Engl J Med 1984;311:819-23.
45. Francis GS, Cohn JN, Johnson GR, et al, for the V-HeFTVA Cooperative Studies Group. Plasma norepinephrine, plasma renin activity, and congestive heart failure: relations to survival and the effects of therapy in V-HeFT II. Circulation 1993;87(suppl 4):40-8.
46. Zipes DP. Influence of myocardial ischemia and infarction on autonomic innervation of the heart. Circulation 1990;82:1095-105.
47. Zipes DP. Sympathetic stimulation and arrhythmias. N Engl J Med 1991;325:656-7.
48. Mitrani RD, Klein LS, Miles WM, et al. Regional cardiac sympathetic denervation in patients with ventricular tachycardia in the absence of coronary artery disease. J Am Coll Cardiol 1993;22:1344-53.
49. Meredith IT, Broughton A, Jennings GL, et al. Evidence of a selective increase in cardiac sympathetic activity in patients with sustained ventricular arrhythmias. N Engl J Med 1991;325:618-24.
50. Mann DL, Kent RL, Parsons B, et al. Adrenergic effects on the biology of the adult mammalian cardiocyte. Circulation 1992;85:790-804.