Pathways of cadmium influx in mammalian neurons

Journal of Neurochemistry

Volumn 72, Issue 5, 1999, Pages 2154-2161

  Usai, Cesare ^a   Barberis, Andrea ^a   Moccagatta, Luca ^a   Marchetti, Carla ^a  

^a CNR   (Italy)

Author keywords

Cadmium uptake; Calcium channel; Fura 2; Glutamate receptors; Neurotoxicity

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; 5,7 DICHLOROKYNURENIC ACID; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; CADMIUM; CALCIUM CHANNEL; CALCIUM ION; CHELATING AGENT; FURA 2; GLUTAMIC ACID; GLYCINE; MAGNESIUM ION; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID; NEUROTOXIN; NIMODIPINE; OMEGA AGATOXIN IVA; OMEGA CONOTOXIN MVIIC; POTASSIUM CHLORIDE; TETRAKIS (2 PYRIDYLMETHYL) ETHYLENEDIAMINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL MEMBRANE PERMEABILITY; CELL MEMBRANE TRANSPORT; CEREBELLUM; CONTROLLED STUDY; GRANULE CELL; MAMMAL CELL; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SPECTROFLUOROMETRY;

ANIMALS; CADMIUM; CALCIUM CHANNEL BLOCKERS; CELLS, CULTURED; CYTOSOL; FLUORESCENT DYES; FURA-2; GLUTAMIC ACID; MODELS, NEUROLOGICAL; NEURONS; OSMOLAR CONCENTRATION; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA; IVA; MAMMALIA;

EID: 0033009376     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0722154.x     Document Type: Article

References (46)

1. Amico C., Marchetti C., Nobile M., and Usai C. (1995) Pharmacological types of calcium channels and their modulation by baclofen in cerebellar granules. J. Neurosci. 15, 2839-2848.
2. Babitch J. (1988) Cadmium neurotoxicity, in Metal Neurotoxicity (Bondy S. and Prasad K., eds), pp. 141-166. CRC Press, Boca Raton, Florida.
3. Bond M., Shuman H., Somlyo A. P., and Somlyo A. V. (1984) Total cytoplasmic calcium in relaxed and maximally contracted rabbit portal vein smooth muscle. J. Physiol. (Lond.) 357, 185-201.
4. Carbone E. and Lux H. D. (1988) Omega-conotoxin blockade distinguishes Ca from Na permeable states in neuronal calcium channels. Pflugers Arch. 413, 14-22.
5. Chao S.-H., Suzuki Y., Zysk J. R., and Cheung W. Y. (1984) Activation of calmodulin by various metal cations as a function of ionic radius. Mol. Pharmacol. 26, 75-82.
6. Choudhuri S., Liu W. L., Berman N. E., and Klaassen C. D. (1996) Cadmium accumulation and metallothionein expression in brain of mice at different stages of development. Toxicol. Lett. 84, 127-133.
7. Clarkson T. W. (1993) Molecular and ionic mimicry of toxic metals. Annu. Rev. Pharmacol. Toxicol. 32, 545-571.
8. Conley C. C. (1996) Extracellular Ligand-Gated Channels. Academic Press, San Diego.
9. De S. K., Dey S. K., and Andrews G. K. (1990) Cadmium teratogenicity and its relationship with metallothionein gene expression in midgestation mouse embryos. Toxicology 64, 89-104.
10. D'Mello S. R., Galli C., Ciotti T., and Calissano P. (1993) Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP. Proc. Natl. Acad. Sci. USA 90, 10989-10993.
11. Endo T. and Shaikh Z. A. (1993) Cadmium uptake by primary cultures of rat renal cortical epithelial cells: influence of cell density and other metal ions. Toxicol. Appl. Pharmacol. 121, 203-209.
12. 2+-induced injury in CNS white matter. J. Neurophysiol. 76, 3264-3273.
13. 2+ in bovine chromaffin cells. FEBS Lett. 283, 89-92.
14. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260, 3440-3450.
15. Hagiwara S. and Byerly L. (1981) Calcium channel. Annu. Rev. Neurosci. 4, 69-125.
16. Hess P. and Tsien R. W. (1984) Mechanism of ion permeation through calcium channels. Nature 309, 453-456.
17. Hille B. (1992) Ionic Channels in Excitable Membranes. p. 108. Sinauer Associates, Sunderland, Massachusetts.
18. Hinkle P. M. and Osborne M. E. (1994) Cadmium toxicity in rat pheochromocytoma cells: studies on the mechanism of uptake. Toxicol. Appl. Pharmacol. 124, 91-98.
19. Hinkle P. M., Kinsella P. A., and Osterhoudt K. C. (1987) Cadmium uptake and toxicity via voltage-sensitive calcium channels. J. Biol. Chem. 262, 16333-16337.
20. Hinkle P. M., Shanshala E. D., and Nelson E. J. (1992) Measurement of intracellular cadmium with fluorescent dyes. Further evidence for the role of calcium channels in cadmium uptake. J. Biol. Chem. 267, 25553-25559.
21. Ishii T., Moriyoshi K., Sugihara H., Sakurada K., Kadotani H., Yokoi M., Azakawa C., Shigemoto R., Mizuno N., Masu M., and Nakanishi S. (1993) Molecular characterization of the family of N-methyl-D-aspartate receptor subunits. J. Biol. Chem. 268, 2836-2843.
22. Jin P. and Ringertz N. R. (1990) Cadmium induces transcription of proto-oncogenes c-jun and c-myc in rat L6 myoblasts. J. Biol. Chem. 265, 14061-14064.
23. Johansson J. S. and Haynes D. H. (1988) Deliberate Quin2 overload as a method for in situ characterization of active calcium extrusion systems and cytoplasmic calcium binding: application to human platelet. J. Membr. Biol. 104, 147-163.
24. Kuo C.-C. and Hess P. (1992) A functional view of the entrances of L-type calcium channels: estimates of the size and surface potential at the pore mouths. Neuron 9, 515-526.
25. ++ pore in rat pheochromocytoma cells. J. Physiol. (Lond.) 466, 657-682.
26. Kwan C.-Y. and Putney J. W. Jr. (1990) Uptake and intracellular sequestration of divalent cations in resting and methacholine-stimulated mouse lacrimal acinar cells. J. Biol. Chem. 265, 678-684.
27. Marchetti C. and Usai C. (1996) High affinity block by nimodipine of the internal calcium elevation in chronically depolarized rat cerebellar granule neurons. Neurosci. Lett. 207, 1-4.
28. Marchetti C., Carignani C., and Robello M. (1991) Voltage-dependent calcium currents in cerebellar granule cells. Neuroscience 43, 121-133.
29. Marchetti C., Amico C., and Usai C. (1995) Functional characterization of the effect of nimodipine on the calcium current in rat cerebellar granule cells. J. Neurophysiol. 73, 1169-1180.
30. 2+ channel pore. FEBS Lett. 335, 265-269.
31. Mishina M., Mori H., Araki K., Kushiya E., Meguro H., Kutsuwada T., Kashiwabuchi N., Ikeda K., Nagasawa M., Yamazaki M., Masaki H., Yamakura T., Morita T., and Sakimura K. (1993) Molecular and functional diversity of the NMDA receptor channel. Ann. NY Acad. Sci. 707, 136-152.
32. 2+ imaging in single living cells: theoretical and practical issues. Cell Calcium 11, 157-179.
33. Recasens M. and Vignes M. (1995) Excitatory amino acid metabotropic receptor subtypes and calcium regulation. Ann. NY Acad. Sci. 757, 418-429.
34. 2 on testes of mice. J. Toxicol. Environ. Health 36, 401-409.
35. Shaikh Z. A., Blazka M. E., and Endo T. (1995) Metal transport in cells: cadmium uptake by rat hepatocytes and renal cortical epithelial cells. Environ. Health Perspect. 103 (Suppl. 1), 73-75.
36. Shibuya I. and Douglas W. W. (1992) Calcium channels in rat melanotrophs are permeable to manganese, cobalt, cadmium, and lanthanum, but not to nickel: evidence provided by fluorescence changes in fura-2 loaded cells. Endocrinology 131, 1936-1941.
37. Sutoo D. (1994) Disturbances of brain function by exogenous cadmium, in The Vulnerable Brain and Environmental Risks, Vol. 3: Toxins in Air and Water (Isaacson R. L. and Jensen K. F., eds), pp. 281-300. Plenum Press, New York.
38. Sutoo D., Akiyama K., and Imamiya S. (1990) A mechanism of cadmium poisoning: the cross effect of calcium and cadmium in the calmodulin-dependent system. Arch. Toxicol. 64, 161-164.
39. Tatsumi H. and Katayama Y. (1994) Calcium homeostasis in the presence of fura-2 in neurons dissociated from rat nucleus basalis: theoretical and experimental analysis of chelating action of fura-2. J. Neurosci. Methods 53, 209-215.
40. 2+. Am. J. Physiol. 259, C762-C768.
41. 2+ entry in isolated bovine chromaffin cells. Biochim. Biophys. Acta 1069, 197-200.
42. von Tscharner V., Deranleau D. A., and Baggiolini M. (1986) Calcium fluxes and calcium buffering in human neutrophils. J. Biol. Chem. 261, 10163-10168.
43. Wetterhahn-Jennette K. (1981) The role of metals in carcinogenesis: biochemistry and metabolism. Environ. Health Perspect. 40, 233-252.
44. 2+ underlying contraction of single smooth muscle cells. Science 235, 1644-1648.
45. Wong K. L. and Klaassen C. D. (1982) Neurotoxic effects of cadmium in young rats. Toxicol. Appl. Pharmacol. 63, 330-337.
46. 2+ channels. Nature 366, 158-161.