A Na+-H+ exchange inhibitor (SM-20550) protects from microvascular deterioration and myocardial injury after reperfusion

European Journal of Pharmacology

Volumn 374, Issue 3, 1999, Pages 355-366

  Ito, Yuichi ^a   Imai, Susumu ^a   Ui, Goro ^a   Nakano, Masayuki ^a   Imai, Kunihiko ^a   Kamiyama, Hiroshi ^a   Naganuma, Fumio ^a   Matsui, Kazuki ^b   Ohashi, Naohito ^b   Nagai, Ryozo ^a  

^a GUNMA UNIVERSITY   (Japan)

^b DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

'No reflow' phenomenon; Arrhythmia; Coronary flow reserve; Myocardial damage; Na+ H+ exchange; Reperfusion

Indexed keywords

ACETYLCHOLINE; ADENOSINE; CARDIOVASCULAR AGENT; N AMIDINO 1,4 DIMETHYL 1H INDOLE 2 CARBOXAMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL INJURY; COLLATERAL CIRCULATION; CONTROLLED STUDY; CORONARY ARTERY CIRCUMFLEX BRANCH; CORONARY VASCULAR RESISTANCE; DOG; DRUG EFFECT; HEART INFARCTION SIZE; HEART MUSCLE BLOOD FLOW; HEART MUSCLE INJURY; HEART PROTECTION; INTRAARTERIAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE; REPERFUSION INJURY;

ACETYLCHOLINE; ADENOSINE; AMIDINES; ANIMALS; CORONARY VESSELS; DOGS; FEMALE; INDOLES; MALE; MICROCIRCULATION; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; PEROXIDASE; RATS; RATS, SPRAGUE-DAWLEY; REGIONAL BLOOD FLOW; SODIUM-HYDROGEN ANTIPORTER; VASCULAR RESISTANCE; VASODILATOR AGENTS;

EID: 0033008899     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00283-6     Document Type: Article

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