Possible involvement of DNA methylation in 5-azacytidine-induced neuronal cell apoptosis

Histology and Histopathology

Volumn 14, Issue 1, 1999, Pages 143-150

  Nakayama, H ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

5 Azacytidine; Apoptosis; Brain; DNA methylation; PC12 cells

Indexed keywords

3 DEAZAADENINE; 3 DEAZAURIDINE; 5 AZA 2' DEOXYCYTIDINE; 5 AZACYTOSINE; 6 AZACYTIDINE; AZACITIDINE; AZAURIDINE; CYTIDINE; CYTIDINE DERIVATIVE; DNA; NUCLEOSIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN; CONTROLLED STUDY; DEMETHYLATION; DNA METHYLATION; FETUS; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PHEOCHROMOCYTOMA CELL; RAT; SPINAL CORD;

ANIMALS; APOPTOSIS; AZACITIDINE; CYTIDINE; DNA METHYLATION; FEMALE; MICE; MICE, INBRED ICR; NEURONS; NUCLEOSIDES; PC12 CELLS; RATS;

EID: 0033008849     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Constantinides P.G., Jones P.A. and Gevers W. (1977). Functional striated muscle cells from non-myoblast precursors following 5-azacytidine treatment. Nature 267, 364-366.
2. Constantinides P.G., Taylor S.M. and Jones P.A. (1978). Phenotypic conversion of cultured mouse embryo cells by aza pyrimidine nucleosides. Dev. Biol. 66, 57-71.
3. Creusot F. and Christman J.K. (1981). Localization of DNA methyltransferase in the chromatin of Friend erythroleukemia cells. Nucleic Acids Res. 9, 5359-5381.
4. Creusot F., Acs G. and Christman J.K. (1982). Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidine and 5-aza-2′-deoxycytidine. J. Biol. Chem. 257, 2041-2048.
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