Dystrophin and beta-dystrpglycan in photoreceptor terminals from normal and mdx3Cv mouse retinae

European Journal of Neuroscience

Volumn 11, Issue 6, 1999, Pages 2121-2133

  Blank, Martina ^a   Koulen, Peter ^a   Blake, Derek J ^b   Kröger, Stephan ^a  

^a MAX PLANCK INSTITUTE FOR BRAIN RESEARCH   (Germany)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Electroretinogram; Muscular dystrophy; Outer plexiform layer; Photoreceptor; Retina

Indexed keywords

DYSTROGLYCAN; DYSTROPHIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAPILLARY BASEMENT MEMBRANE; CELL ULTRASTRUCTURE; COGNITIVE DEFECT; ELECTRORETINOGRAM; GENE MUTATION; IMMUNOREACTIVITY; MOUSE; MUSCULAR DYSTROPHY; NERVE ENDING; NONHUMAN; PHENOTYPE; PHOTORECEPTOR; PRIORITY JOURNAL; RETINA; RETINA CONE; RETINA ROD;

ANIMALS; BLOTTING, WESTERN; CYTOSKELETAL PROTEINS; DYSTROGLYCANS; DYSTROPHIN; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, INBRED MDX; MICROSCOPY, ELECTRON; NERVE ENDINGS; PHOTORECEPTORS, VERTEBRATE; REFERENCE VALUES; RETINA; RODS (RETINA); TISSUE DISTRIBUTION;

EID: 0033008768     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.1999.00636.x     Document Type: Article

References (42)

1. Araki, E., Nakamura, K., Nakao, K., Kameya, S., Kobayashi, O., Nonaka, I., Kobayashi, T. & Katsuki, M. (1997) Targeted disruption of exon 52 in the mouse dystrophin gene induced muscle degeneration similar to that observed in Duchenne muscular dystrophy. Biochem. Biophys. Res. Commun., 238, 492-497.
2. Bewick, G.S., Nicholson, L.V.B., Young, C. & Slater, C.R. (1993) Relationship of a dystrophin-associated glycoprotein to junctional acetylcholine receptor clusters in rat skeletal muscle. Neuromusc. Disord., 3, 503-506.
3. Blake, D.J., Tinsley, J.M. & Davies, K.E. (1996) Utrophin: a structural and functional comparison to dystrophin. Brain Pathol., 6, 37-47.
4. Blake, D.J., Nawrotzki, R., Loh, N.Y., Gorecki, D.C. & Davies, K.E. (1998) Beta-dystrobrevin, a member of the dystrophin-related protein family. Proc. Natl Acad. Sci. USA, 95, 241-246.
5. Blank, M., Koulen, P. & Kröger, S. (1997) Subcellular concentration of beta-dystroglycan in photoreceptors and glial cells of the chick retina. J. Comp. Neurol., 389, 668-678.
6. Brown, R.H. (1996) Dystrophin-associated proteins and the muscular dystrophies: a glossary. Brain Pathol., 6, 19-24.
7. Campbell, K.P. (1995) Three muscular dystrophies: loss of cytoskeleton-extracellular matrix linkage. Cell, 80, 675-679.
8. Campbell, K.P. & Kahl, S.D. (1989) Association of dystrophin and an integral membrane glycoprotein. Nature, 338, 259-262.
9. Carter-Dawson, L.D. & LaVail, M.M. (1979) Rods and cones in the mouse retina. I. Structural analysis using light and electron microscopy. J. Comp. Neurol., 188, 245-262.
10. Chapman, V.M., Miller, D.R., Armstrong, D. & Caskey, C.T. (1989) Recovery of induced mutations for X chromosome-linked muscular dystrophy in mice. Proc. Natl Acad. Sci. USA, 86, 1292-1296.
11. Cibis, G.W., Fitzgerald, K.M., Harris, D.J., Rothberg, P.G. & Rupani, M. (1993) The effects of dystrophin gene mutations on the ERG in mice and humans. Invest. Ophthalmol. Vis. Sci., 34, 3646-3652.
12. Cox, G.A., Phelps, S.F., Chapman, V.M. & Chamberlain, J.S. (1993) New mdx mutation disrupts expression of muscle and nonmuscle isoforms of dystrophin. Nature Genet, 4, 87-93.
13. Cullen, M.J., Walsh, J. & Nicholson, L.V.B. (1994) Immunogold localization of the 43-kDa dystroglycan at the plasma membrane in control and dystrophic human muscle. Acta Neuropathol., 87, 349-354.
14. D'Souza, V.N., Nguyen, T.M., Morris, G.E., Karges, W., Pillers, D.M. & Ray, P.N. (1995) A novel dystrophin isoform is required for normal retinal electrophysiology. Hum. Mol. Gen., 4, 837-842.
15. Drenckhahn, D., Holbach, M., Ness, W., Schmilz, F. & Anderson, L.V.B. (1996) Dystrophin and the dystrophin-associated glycoprotein, β-dystroglycan, co-localize in photoreceptor synaptic complexes of the human retina. Neuroscience, 73, 605-612.
16. Eldred, W.D., Zucker, C., Karten, HJ. & Yazulla, S. (1983) Comparison of fixation and penetration enhancement techniques for use in ultrastructural immunocytochemistry. J. Histochem. Cytochem., 31, 285-292.
17. Ervasti, J.M. & Campbell, K.P. (1991) Membrane organization of the dystrophin-glycoprotein complex. Cell, 66, 1121-1131.
18. Euler, T. & Wässle, H. (1995) Immunocytochemical identification of cone bipolar cells in the rat retina. J. Comp. Neurol., 361, 461-478.
19. Fitzgerald, K.M., Cibis, G.W., Giambrone, S.A. & Harris, D.J. (1994) Retinal signal transmission in Duchenne muscular dystrophy: evidence for dysfunction in the photoreceptor/depolarizing bipolar cell pathway. J. Clin. Invest., 93, 2425-2430.
20. Gorecki, D.C., Deny, J.M. & Barnard, E.A. (1994) Dystroglycan: brain localisation and chromosome mapping in the mouse. Hum. Mol. Gen., 3, 1589-1597.
21. Greferath, U., Grünert, U. & Wässle, H. (1990) Rod bipolar cells in the mammalian retina show protein kinase C-like immunoreactivity. J. Comp. Neurol, 301, 433-442.
22. Henry, M.D. & Campbell, K.P. (1996) Dystroglycan: an extracellular matrix receptor linked to the cytoskeleton. Curr. Opin. Cell Biol., 8, 625-631.
23. Jensen, H., Warburg, M., Sjö, O. & Schwanz, M. (1995) Duchenne muscular dystrophy: negative electroretinograms and normal dark adaptation: reappraisal of assignment of X-linked incomplete congenital stationary night blindness. J. Med. Genet. 348-351.
24. Jeon, C.J., Strettoi, E. & Masland, R.H. (1998) The major cell populations of the mouse retina. J. Neurosci., 18, 8936-8946.
25. Kameya, S., Araki, E., Katsuki, M., Mizota, A., Adachi, E., Nakahara, K., Nonaka, I., Sakuragi, S., Takeda, S. & Nabeshima, Y. (1997) Dp260 disrupted mice revealed prolonged implicit time of the b-wave in ERG and loss of accumulation of β-dystroglycan in the outer plexiform layer of the retina. Hum. Mol. Gen., 6, 2195-2203.
26. Kirsch, J. & Betz, H. (1995) The postsynaptic localization of the glycine receptor-associated protein gephyrin is regulated by the cytoskeleton. J. Neurosci., 15, 4148-1156.
27. Koulen, P., Blank, M. & Kröger, S. (1998) Differential distribution of beta-dystroglycan in rabbit and rat retina. J. Neurosci. Res., 51, 735-747.
28. Kröger, S. & Mann, S. (1996) Biochemical and functional characterization of basal lamina-bound agrin in the chick central nervous system. Eur. J. Neurosci., 8, 500-509.
29. Lambrecht, H.-G. & Koch, K.-W. (1992) Recoverin, a novel calcium-binding protein from vertebrate photoreceptors. Biochim. Biophys. Acta, 1160, 63-66.
30. Lenk, U., Oexle, K., Voit, T., Ancker, U., Hellner, K.A., Speer, A. & Hübner, C. (1996) A cysteine 3340 substitution in the dystroglycan-binding domain of dystrophin associated with Duchenne muscular dystrophy, mental retardation and absence of the ERG b-wave. Hum. Mol. Gen., 5, 973-975.
31. Lidov, H.G. (1996) Dystrophin in the nervous system. Brain Pathol., 6, 63-77.
32. Love, D.R., Hill, D.F., Dickson, G., Spurr, N.K., Byth, B.C., Marsden, R.F., Walsh, F.S., Edwards, Y.H. & Davies, K.E. (1989) An autosomal transcript in skeletal muscle with homology to dystrophin. Nature, 339, 55-58.
33. Mann, S. & Kröger, S. (1996) Agrin is synthesized by retinal cells and colocalizes with gephyrin. Mol. Cell. Neurosci., 8, 1-13.
34. Masu, M., Iwakabe, H., Tagawa, Y., Miyoshi, T., Yamashita, M., Fukuda, Y., Sasaki, H., Hiroi, K., Nakamura, Y., Shigemoto, R., Takada, M., Nakamura, K., Nakao, K., Katsuki, M. & Nakanishi, S. (1995) Specific deficit of the ON response in visual transmission by targeted disruption of the mGluR6 gene. Cell, 80, 757-765.
35. McGinnis, J.F., Stepanik, P.L., Jariangpra'sert, S. & Lerious, V. (1997) Functional significance of recoverin localization in multiple retina cell types. J. Neurosci. Res., 50, 487-195.
36. Make, T., Miyatake, M., Zhao, J., Yoshioka, K. & Uchino, M. (1989) Immunohistochemical dystrophin reaction in synaptic regions. Brain Dev., 11, 344-346.
37. Montanaro, F., Carbonetto, S., Campbell, K.P. & Lindenbaum, M. (1995) Dystroglycan expression in the wild type and mdx mouse neural retina: synaptic colocalization with dystrophin, dystrophin-related protein but not laminin. J. Neurosci. Res., 42, 528-538.
38. Ohlendieck, K., Ervasti, J.M., Matsumura, K., Kahl, S.D., Leveille, C.J. & Campbell, K.P. (1991) Dystrophin-related protein is localized to neuromuscular junctions of adult skeletal muscle. Neuron, 7, 499-508.
39. Peichl, L. & Gonzalez-Soriano, J. (1994) Morphological types of horizontal cell in rodent retinae: a comparison of rat, mouse, gerbil, and guinea pig. Vis. Neurosci., 11, 501-517.
40. Pillers, D.M., Bulman, D.E., Weleber, R.G., Sigesmund, D.A., Musarella, M.A., Powell, B.R., Murphey, W.H., Westall, C., Panton, C., Becker, L.E., Worton, R.G. & Ray, P.N. (1993) Dystrophin expression in the human retina is required for normal function as defined by electroretinography. Nature Genet., 4, 82-86.
41. Cv3 mouse is a model for electroretinography of Duchenne/Becker muscular dystrophy. Invest. Ophthalmol. Vis. Sci., 36, 462-166.
42. Ripps, H. (1982) Night blindness revisited: From man to molecules. Invest. Ophthalmol. Vis. Sci., 23, 588-601.