Changes in rat testicular antioxidant defence profile as a function of age and its impairment by hexachlorocyclohexane during critical stages of maturation

Andrologia

Volumn 31, Issue 2, 1999, Pages 83-90

  Samanta, L ^a   Roy, A ^a   Chainy, G B N ^a  

^a UTKAL UNIVERSITY   (India)

Author keywords

Antioxidant enzymes; ATPase; Hexachlorocyclohexane; Lipid peroxidation; Spermatogenesis; Testis

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ANTIOXIDANT; CATALASE; HEXACHLOROCYCLOHEXANE; SUPEROXIDE DISMUTASE;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MATURATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME METABOLISM; LIPID PEROXIDATION; NONHUMAN; OXIDATIVE STRESS; RAT; SEXUAL MATURATION; SPERMATOGENESIS; TESTIS DEVELOPMENT; TESTIS FUNCTION;

AGING; ANIMALS; ANTIOXIDANTS; CA(2+) MG(2+)-ATPASE; CATALASE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; INSECTICIDES; LINDANE; LIPID PEROXIDATION; MALE; MITOCHONDRIA; RATS; SPERMATOGENESIS; SUPEROXIDE DISMUTASE; TESTIS;

EID: 0033008182     PISSN: 03034569     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1439-0272.1999.00232.x     Document Type: Article

References (19)

1. Bagchi M, Stohs SJ (1993) In vitro induction of reactive oxygen species by 2,3,7,8-tetrachlorodibenzo-p-dioxin, endrin and lindane in rat peritoneal macrophages and hepatic mitochondria and microsomes. Free Rad Biol Med 14:11-18.
2. Barman TE (1974) Enzymes handbook, (Suppl. I) Springer-Verlag, New York, pp. 136-137.
3. Bauche F, Fouchard M, Jegou B (1994) Antioxidant system in rat testicular cells. FEBS Letters 349:392-396.
4. Bus JS, Gibson JE (1979) Lipid peroxidation and its role in toxicology. In: Reviews in Biochemical Toxicology. Hodgson E, Bend JR, Philpot RM (eds) Elsevier, North-Holland, New-York, pp. 125-149.
5. Chainy GBN, Samantaray S, Samanta L (1997)Testosterone-induced changes in testicular antioxidant system. Andrologia 29:343-349.
6. 2+)-adenosine triphosphatase activity in rat testis throughout maturation. J Reprod Fert 33:513-517.
7. Georgiou M, Perkins LM, Payne AH (1987) Steroidsynthesis-dependent, oxygen-mediated damage of mitochondrial and microsomal cytochrome P-450 enzymes in rat Leydig cell cultures. Endocrinology 121:1390-1399.
8. Hall PF (1994) Testicular steroid synthesis: organiation and regulation. In: The Physiology of Reproduction, Vol 1. Knobil E, Neil JD (eds) Raven Press, New York, pp. 1335-1362.
9. Johnson AD (1970) Testicular lipids. In: The Testis, Vol 2. Johnson AD, Gomes WR, Vandermark NL(eds) Academic Press, New York, London, pp. 193-258.
10. 2-production and calcium release in human polymorphonuclear leucocytes. Blood 68:535-540.
11. Lehninger AL, Nelson DL, Cox MM (1993) Principles of Biochemistry. CBS Publishers & Distributors, Delhi, 216 pp.
12. Oberley LW, Oberley TD, Buettner GR (1981) Cell division in normal and transformed cells: the possible role of superoxide and hydrogen peroxide. Medical Hypothesis 7:21-42.
13. Peltola V, Huhtaniemi I, Ahotupa M (1992) Antioxidant enzyme activity in the maturing rat testis. J Androl 13:450-455.
14. Pius J, Shivanandappa T, Krishnakumari MK (1990) Protective role of vitamin A in the male reproductive toxicity of hexachlorocyclohexane (HCH) in the rat. Reprod Toxicol 4:325-330.
15. Pradeep KG, Sccrwani N, Laloraya N, Nivsarkar M, Verma S, Singh A (1990) Superoxide dismutase as a regulatory switch in mammalian testicular steroidogenesis. Biochem Biophys Res Commun 173:302-308.
16. Roy A, Chainy GBN (1996) Age-related change in rat testicular ATPase activities in response to HCH treatment. Bull Environ Contam Toxicol 56:165-170.
17. Samanta L, Chainy GBN (1997) Comparison of hexachlorocyclohexane-induced oxidative stress in the testis of immature and adult rats. Comp Biochem Physiol 118C:319-327.
18. Tomaoki BI (1973) Steroidogenesis and cell structure. Biomchemical pursuit of sites of steroid biosynthesis. J Steroid Biochem 4:89-118.
19. Weisiger RA, Fridovich I (1973) Mitochondrial superoxide dismutase. Site of synthesis and intramitochondrial localization. J Biol Chem 248:4793-4796.