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Connolly, H.M.1
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Cardiac valvulopathy associated with exposure to fenfluramine or dexfenfluramine
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The prevalence of cardiac valvular insufficiency assessed by transthoracic echocardiography in obese patients treated with appetite suppressant drugs
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Low incidence of valvular heart disease in 226 phentermine-fenfluramine protocol subjects prospectively followed for up to 30 months
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Fen-phen use is not associated with an increased prevalence of significant valvular heart disease
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abstract 3391
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Lopez-Jimenez F, Aldrich HR, Kumar V, et al. Fen-phen use is not associated with an increased prevalence of significant valvular heart disease. Circulation. 1998;98(17):I644 (abstract 3391).
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Prevalence of valvular regurgitation in patients exposed to anorectic agents
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Salti, H.2
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Combination therapy with fenfluramine-phentermine increases the risk of significant aortic insufficiency
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abstract 3394
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Gross SB, Samuels BA, Daley WL, et al. Combination therapy with fenfluramine-phentermine increases the risk of significant aortic insufficiency. Circulation. 1998;98(17):I644 (abstract 3394).
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Catecholamines, sympathomimetic drugs, and adrenergic receptor antagonists
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Hardman JG, Gilman AG, Limbird LE (eds). New York, NY: McGraw-Hill
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5-Hydroxytryptamine serotonin receptor agonists and antagonists
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Hardman JG, Gilman AG, Limbird LE (eds). New York, NY: McGraw-Hill
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Sanders-Bush E, Mayer SE. 5-Hydroxytryptamine (serotonin receptor agonists and antagonists. In: Hardman JG, Gilman AG, Limbird LE (eds). Goodman of Gilman's The Pharmacological Basis of Therapeutics. 9th ed. New York, NY: McGraw-Hill, 1996:249-263.
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Prescribing information for Meridia® sibutramine hydrochloride monohydrate
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Prescribing information for Prozac® (fluoxetine hydrochloride)
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Absence of cardiac valve dysfunction in obese patients treated with sibutramine
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abstract 3389
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Bach, D.S.1
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