Interferon-α elevates pulmonary blood pressure in sheep - The role of thromboxane cascade

European Journal of Pharmacology

Volumn 370, Issue 2, 1999, Pages 145-151

  Hanaoka, Masayuki ^a   Kubo, Keishi ^a   Hayano, Toshihide ^a   Koizumi, Tomonobu ^a   Kobayashi, Toshio ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Interferon ; Permeability; Pulmonary hypertension; Sheep; Thromboxane A2

Indexed keywords

ALPHA INTERFERON; OZAGREL; THROMBOXANE A2;

ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL PERMEABILITY; INTRAVENOUS DRUG ADMINISTRATION; LUNG ARTERY PRESSURE; NONHUMAN; PRIORITY JOURNAL; PULMONARY HYPERTENSION; SHEEP;

6-KETOPROSTAGLANDIN F1 ALPHA; ANALYSIS OF VARIANCE; ANIMALS; ANTIVIRAL AGENTS; BODY TEMPERATURE; CAPILLARY PERMEABILITY; ENZYME INHIBITORS; HEMODYNAMIC PROCESSES; HYPERTENSION, PULMONARY; INFUSIONS, INTRAVENOUS; INTERFERON-ALPHA; LUNG; METHACRYLATES; SHEEP; THROMBOXANE B2; THROMBOXANE-A SYNTHASE;

EID: 0033007853     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00107-7     Document Type: Article

References (38)

1. Balkwill F.R. Interferons. Lancet. 1:1989;1060-1063.
2. Durum, S.K., Oppenheim, J.J., 1993. Proinflammatory cytokines and immunity. In: Paul, W.E. (Ed), Fundamental Immunology. Raven Press, New York, pp. 801-835.
3. Friedman, C., Merigan, T., Sreevalsan, T., 1986. Interferons as Cell Growth Inhibitors and Antitumor Factors. Alan R. Liss, New York.
4. Gerrard T.L., Siegel J.P., Dyer D.R., Zoon K.C. Differential effects of interferon α and interferon γ on interleukin 1 secretion by monocytes. J. Immunol. 138:1987;2535-2540.
5. Greenberg H.B., Pollard R.B., Lutwick L.I., Gregory P.B., Robinson W.S., Merigan T.C. Effect of human leukocyte interferon on hepatitis B virus infection in patients with chronic active hepatitis. N. Engl. J. Med. 295:1976;517-522.
6. Hanaoka M., Kubo K., Miyahara T., Hayano T., Koizumi T., Kobayashi T., Sekiguchi M. Effect of post-treatment with granulocyte colony-stimulating factor on endotoxin-induced lung injury in sheep. Exp. Lung Res. 24:1998;15-25.
7. 2 synthetase inhibitor (E)-3-[p-(1H-imidazol-1-ylmethyl) phenyl]-2-propenoic acid (OKY-046). Japan J. Pharmacol. 41:1986;393-401.
8. Hizawa N., Kojima J., Kojima T., Sukoh N., Yamaguchi E., Kawakami Y., Matsushima T. A patient with chronic hepatitis C who simultaneously developed interstitial pneumonia, hemolytic anemia and cholestatic liver dysfunction after alpha-interferon administration. Intern. Med. 33:1994;337-341.
9. Hoffman T., Lizzio E.F., Ting A., Marshall L.A., Bonvini E., Jennings M.K. Release of arachidonic acid metabolites by human monocytes or lymphocytes: effect of treatment with interferon on stimulation by phorbol ester or calcium ionophore. Clin. Immunol. Immunopathol. 44:1987;82-92.
10. Isaacs A., Lindemann J. Virus interference: I. The interferon. Proc. R. Soc. Lond. B: Biol. Sci. 147:1957;258-263.
11. Jaffe B.M., Behrman H.R., Parker C.W. Radioimmunoassay measurement of prostaglandin E, A, F in human plasma. J. Clin. Invest. 52:1973;398-405.
12. Joklik, W.K., 1990. Interferons. In: Fields, B.N., Knipe, D.M. (Eds.), Virology. Raven Press, New York, pp. 383-410.
13. Kamisako T., Adachi Y., Chihara J., Yamamoto T. Interstitial pneumonitis and interferon-alpha. B.M.J. 306:1993;896.
14. Kelley J. Cytokines of the lung. Am. Rev. Respir. Dis. 141:1990;765-788.
15. 2 mediates increased pulmonary microvascular permeability following limb ischemia. Circ. Res. 64:1989;1178-1189.
16. Koizumi T., Kubo K., Kobayashi T., Sekiguchi M. Effects of thromboxane synthase inhibition on tumor necrosis factor-induced lung injury in sheep. J. Appl. Physiol. 73:1992;618-624.
17. Koizumi T., Kubo K., Shinozaki S., Koyama S., Kobayashi T., Sekiguchi M. Granulocyte colony-stimulating factor does not exacerbate endotoxin-induced lung injury in sheep. Am. Rev. Respir. Dis. 148:1993;132-137.
18. Koyama S., Kobayashi T., Kubo K., Sekiguchi M., Ueda G. Recombinant-human superoxide dismutase attenuates endotoxin-induced lung injury in awake sheep. Am. Rev. Respir. Dis. 145:1992;1404-1409.
19. Kubo K., Kobayashi T. Effects of OKY-046, a selective thromboxane synthetase inhibitor, on endotoxin-induced lung injury in unanesthetized sheep. Am. Rev. Respir. Dis. 132:1985;494-499.
20. Kubo K., Kobayashi T., Hayano T., Koizumi T., Honda T., Sekiguchi M., Sakai A. Effects of ONO-5046, a specific neutrophil elastase inhibitor, on endotoxin-induced lung injury in sheep. J. Appl. Physiol. 77:1994;1333-1340.
21. Mellstedt H., Ahre A., Bjorkholm M., Holm G., Johansson B., Strander H. Interferon therapy in myelomatosis. Lancet. 1:1979;245-247.
22. Moore R.N., Larsen H.S., Horohov D.W., Rouse B.T. Endogenous regulation of macrophage proliferative expansion by colony-stimulating factor-induced interferon. Science. 223:1984;178-181.
23. Moriya K., Yasuda K., Koike K., Ichinose Y., Yotsuyanagi H., Kurokawa K., Iino S. Induction of interstitial pneumonitis during interferon treatment for chronic hepatitis C. J. Gastroenterol. 29:1994;514-517.
24. Motta A.B., Franchi A.M., Gimeno M.F. Role of interferon-alpha in arachidonic acid metabolism by the rat uteri from spayed animals: effect of 17 beta-estradiol. Prostaglandins Leukotrienes Essent. Fatty Acids. 53:1995;267-271.
25. O'Sullivan M.G., Fleisher L.N., Olson N.C., MacLachlan N.J., Brown T.T. Jr. Modulation of arachidonic acid metabolism by bovine alveolar macrophages exposed to interferons and lipopolysaccharide. Am. J. Vet. Res. 51:1990;1820-1825.
26. Shindo M., Di Bisceglie A.M., Cheung L., Shih J.W., Cristiano K., Feinstone S.M., Hoofnagle J.H. Decrease in serum hepatitis C viral RNA during alpha-interferon therapy for chronic hepatitis C. Ann. Intern. Med. 115:1991;700-704.
27. Staeheli P. Interferon induced proteins and the antiviral state. Adv. Virus Res. 38:1990;147-200.
28. Staub N.C., Bland R.D., Brigham K.L., Demling R., Erdman A.J. III, Woolverton W.C. Preparation of chronic lung fistulas in sheep. J. Surg. Res. 19:1975;315-320.
29. 2 levels in patients with classic and variant pectoris. Circulation. 64:1981;1107-1115.
30. Talpaz M., McCredie K.B., Mavligit G.M., Gutterman J.U. Leukocyte interferon-induced myeloid cytoreduction in chronic myelogenous leukemia. Blood. 62:1983;689-692.
31. 2 mediates increased pulmonary microvascular permeability after intestinal reperfusion. J. Appl. Physiol. 82:1997;592-598.
32. Vial T., Descotes J. Clinical toxicity of the interferons. Drug Saf. 10:1994;115-150.
33. Vilcek, J., DeMaeyer, E., 1984. Interferons and the Immune System. Elsevier, Amsterdam, pp. 1-268.
34. Welles S.L., Shepro D., Hechtman H.B. Eicosanoid modulation of stress fibers in cultured bovine endothelial cells. Inflammation. 9:1985;439-450.
35. Yoshikawa J., Kimura K., Takasugi M. Pharmacokinetics of natural IFN-α Antibiotics and Chemotherapy. 3:1987;79-85.
36. 2 analogue and prostacyclin on lung fluid balance in newborn lambs. Circ. Res. 65:1989;1409-1416.
37. Yufu Y., Yamashita S., Nishimura J., Nawata H., Hirata J. Interstitial pneumonia caused by interferon-alpha in chronic myelogenous leukemia. Am. J. Hematol. 47:1994;253.
38. Zamora C.A., Baron D.A., Heffner J.E. Thromboxane contributes to pulmonary hypertension in ischemia-reperfusion lung injury. J. Appl. Physiol. 74:1993;224-229.