Delayed-type hypersensitivity reactions to Onchocerca volvulus antigens in exposed and non-exposed African individuals

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 93, Issue 1, 1999, Pages 103-105

  Burchard, Gerd Dieter ^a   Brattig, Norbert W ^a   Kruppa, Thomas F ^a   Horstmann, Rolf D ^a  

^a BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

Author keywords

Delayed type hypersensitivity; Guinea; Onchocerca volvulus; Onchocerciasis

Indexed keywords

PARASITE ANTIGEN;

ADOLESCENT; ADULT; AFRICA; ARTICLE; CONTROLLED STUDY; CROSS REACTION; DELAYED HYPERSENSITIVITY; FEMALE; HELPER CELL; HUMAN; MAJOR CLINICAL STUDY; MALE; NEMATODE; NONHUMAN; ONCHOCERCA VOLVULUS; ONCHOCERCIASIS; PUERPERAL INFECTION; SCHOOL CHILD;

NEMATODA; ONCHOCERCA VOLVULUS;

EID: 0033007746     PISSN: 00359203     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0035-9203(99)90199-2     Document Type: Article

References (21)

1. Allen, J. E. & Maizels, R. M. (1997). Th1-Th2: reliable paradigm or dangerous dogma? Immunology Today, 18, 387-392.
2. Akhtaruzzaman, K. M., Bienzle, U., Rosenkaimer, F., Guggenmoos, R. & Dietrich, M. (1978). Comparison of different methods for the detection of intestinal protozoa and helminths in stool. Tropenmedizin und Parasitologie, 29, 427-431.
3. Bartlett, A., Turk, J., Ngu, J., Mackenzie, C. D., Fuglsang, H. & Anderson, J. (1978). Variation in delayed hypersensitivity in onchocerciasis. Transactions of the Royal Society of Tropical Medicine and Hygiene, 72, 372-377.
4. Brattig, N. W., Krawietz, I., Abakar, A. Z., Erttmann, K. D., Kruppa, T. F. & Massougbodji, A. (1994). Strong IgG isotypic antibody response in sowdah type onchocerciasis. Journal of Infectious Diseases, 170, 955-961.
5. Brattig, N., Nietz, C., Hounkpatin, S., Lucius, R., Seeber, F., Pichlmeier, U. & Pogonka, T. (1997a). Differences in cytokine responses to Onchocerca volvulus extract and recombinant Ov33 and OvL3-1 proteins in exposed subjects with various parasitologic and clinical states. Journal of Infectious Diseases, 176, 838-842.
6. Brattig, N. W., Henkle-Dührsen, K., Hounkpatin, S., Liebau, E., Kruppa, T. F. & Zipfel, P. F. (1997b). Characterization of human immune responses to the cytosolic Superoxide dismutase and glutathione S-transferase from Onchocerca volvulus. Tropical Medicine and International Health, 2, 788-798.
7. Büttner, D. W., Laer, G. V., Mannweiler, E. & Büttner, M. (1982). Clinical, parasitological and serolpgical studies on onchocerciasis in the Yemen Arab Republic. Tropenmedizin und Parasitologie, 33, 201-212.
8. Cher, D. J. & Mosmann, T. R. (1987). Two types of murine T cell clone. II. Delayed-type hypersensitivity is mediated by Th1 clones. Journal of Immunology, 138, 3688-3694.
9. Cua, D. J., Coffman, R. L. & Stohlman, S. A. (1996). Exposure to T helper 2 cytokines in vivo before encounter with antigen selects for T helper subsets via alterations in antigen-presenting cell function. Journal of Immunology, 157, 2830-2836.
10. Elson, L. H., Guderian, R. H., Araujo, E., Bradley, J. E., Days, A. & Nutman, T. B. (1994). Immunity to onchocerciasis: identification of a putatively immune population in a hyperendemic area of Ecuador. Journal of Infectious Diseases, 169, 588-594.
11. Elson, L. H., Calvopina, M., Paredes, W., Araujo, E., Bradley, J. E., Guderian, R. H. & Nutman, T. B. (1995). Immunity to onchocerciasis: putative immune persons produce a Th1-like response to Onchocerca volvulus. Journal of Infectious Diseases, 171, 652-658.
12. Elson, L. H., Days, A., Calvopina, M., Paredes, W., Araujo, E., Guderian, R. H., Bradley, J. E. & Nutman, T. B. (1996). In utero exposure to Onchocerca volvulus: relationship to subsequent infection intensity and cellular immune responsiveness. Infection and Immunity, 64, 5061-5065.
13. Gallin, M., Edmonds, K., Ellner, J. J., Erttmann, K. D., White, A. T., Newland, H. S., Taylor, H. R. & Greene, B. M. (1988). Cell-mediated immune responses in human infection with Onchocerca volvulus. Journal of Immunology, 140, 1999-2007.
14. Greene, B. M., Fanning, M. M. & Ellner, J. J. (1983). Non-specific suppression of antigen-induced lymphocyte blastogenesis in Onchocerca volvulus infection in man. Clinical and Experimental Immunology, 52, 259-265.
15. Ngu, J. L. (1978). Immunological studies on onchocerciasis. Varying skin hypersensitivity and leucocyte migration inhibition in a clinical spectrum of the disease. Acta Tropica, 35, 269-279.
16. Ottesen, E. A. (1995). Immune responsiveness and the pathogenesis of human onchocerciasis. Journal of Infectious Diseases, 171, 659-671.
17. Philipp, M. & Rumjaneck, F. D. (1984). Antigenic and dynamic properties of helminth surface structures. Molecular and Biochemical Parasitology, 10, 245-268.
18. Soboslay, P. T., Lüder, C. G. K., Hoffmann, W. H., Michaelis, I., Helling, G., Heuschkel, C., Dreweck, C. M., Blanke, C. H., Pritze, S., Banla, M. & Schulz-Key, H. (1994). Ivermectin-facilitated immunity in onchocerciasis: activation of parasite-specific Th1-type responses with subclinical Onchocerca volvulus infection. Clinical and Experimental Immunology, 96, 238-244.
19. Soboslay, P. T., Geiger, S. M., Weiss, N., Banla, M., Lüder, C. G., Dreweck, C. M., Batchassi, E., Boatin, B. A., Stadler, A. & Schulz-Key, H. (1997). The diverse expression of immunity in humans at distinct states of Onchocerca volvulus infection. Immunology, 90, 592-599.
20. Steel, C. & Nutman, T. B. (1993). Regulation of IL-5 in onchocerciasis. A critical role for IL-2. Journal of Immunology, 150, 5511-5518.
21. Ward, D. J., Nutman, T. B., Zea Flores, G., Portocarrero, C., Lujan, A. & Ottesen, E. A. (1988). Onchocerciasis and immunity in humans: enhanced T cell responsiveness to parasite antigen in putatively immune individuals. Journal of Infectious Diseases, 157, 536-543.