Dose-dependent plasma clearance of MK-826, a carbapenem antibiotic, arising from concentration-dependent plasma protein binding in rats and monkeys

Journal of Pharmaceutical Sciences

Volumn 88, Issue 2, 1999, Pages 277-280

  Wong, Bradley K ^a   Bruhin, Patrick J ^a   Lin, Jiunn H ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ERTAPENEM; SERUM ALBUMIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; DOSE RESPONSE; DRUG CLEARANCE; MONKEY; NONHUMAN; PROTEIN ANALYSIS; PROTEIN BINDING; RAT; SPECIES DIFFERENCE;

EID: 0033007586     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js980232k     Document Type: Article

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