Role of K+ channels and sodium pump in the vasodilation induced by acetylcholine, nitric oxide, and cyclic GMP in the rabbit aorta

General Pharmacology

Volumn 33, Issue 1, 1999, Pages 35-41

  Ferrer, M ^a   Marin J ^a   Encabo, A ^a   Alonso, M J ^a   Balfagon G ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

8 Bromo cyclic GMP; Acetylcholine; Nitric oxide; Ouabain; Potassium channel blockers; Rabbit aorta

Indexed keywords

4 AMINOPYRIDINE; 8 BROMO CYCLIC GMP; ACETYLCHOLINE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); APAMIN; BARIUM CHLORIDE; CHARYBDOTOXIN; CYCLIC GMP; GLIBENCLAMIDE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; OUABAIN; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT;

ANIMAL TISSUE; AORTA; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT; VASCULAR ENDOTHELIUM; VASODILATATION;

ACETYLCHOLINE; ANIMALS; AORTA, THORACIC; CYCLIC GMP; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; MALE; MUSCLE TONUS; NA(+)-K(+)-EXCHANGING ATPASE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; OUABAIN; POTASSIUM; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; RABBITS; VASODILATION; VASODILATOR AGENTS;

EID: 0033007361     PISSN: 03063623     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-3623(98)00259-6     Document Type: Article

References (39)

1. + and calcium channels. Br J Pharmac 100, 427-434.
2. Alonso, M.J., Salaices, M., Sánchez-Ferrer, C.F., Marín, J., 1992. Pre-dominant role for nitric oxide in the relaxations induced by acetylcholine in cat cerebral arteries. J Pharmac Exp Ther 261, 12-21.
3. Ca channel antagonists reduce NO donor-mediated relaxation of vascular and tracheal smooth muscle. Am J Physiol 268, L152-L159.
4. Bolotina, V.M., Najibi, S., Palacino, J.J., Pagano, P.J., Cohen, R.A., 1994. Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle. Nature 368, 850-853.
5. Brayden, J.E., 1990. Membrane hyperpolarization is a mechanism of endothelium-dependent cerebral vasodilation. Am J Physiol 259, H668-H673.
6. Chen, G., Suzuki, H., Weston, A.H., 1988. Acetylcholine releases endothelium-derived hyperpolarizing factor and EDRF from rat blood vessels. Br J Pharmac 95, 1165-1174.
7. Chen, G., Hashitani, H., Suzuki, H., 1989. Endothelium-dependent relaxation and hyperpolarization of canine coronary artery smooth muscles in relation to the electrogenic Na-K pump. Br J Pharmac 98, 950-956.
8. + channels contributes to vascular tone. Am J Physiol 267, H1135-H1141.
9. Eckman, D.M., Frankovich, J.D., Keef, K.D., 1992. Comparison of the actions of acetylcholine and BRL 38227 in the guinea-pig coronary artery. Br J Pharmac 106, 9-16.
10. Feletou, M., Vanhoutte, P.M., 1988. Endothelium-dependent hyperpolarization of canine coronary smooth muscle. Br J Pharmac 93, 515-524.
11. Ferrer, M., Encabo, A., Conde, M.V., Marín, J., Balfagón, G., 1995. Heterogeneity of endothelium-dependent mechanisms in different rabbit arteries. J Vasc Res 32, 339-346.
12. Furchgott, R.F., Zawadzki, J.V., 1980. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288, 373-376.
13. Garland, C.G., McPherson, G.A., 1992. Evidence that nitric oxide does not mediate the hyperpolarization and relaxation to acetylcholine in the rat small mesenteric artery. Br J Pharmac 105, 429-435.
14. Hwa, J.J., Ghibauci, L., Williams, P., Chatterjee, M., 1994. Comparison of acetylcholine-dependent relaxation in large and small arteries of rat mesenteric vascular bed. Am J Physiol 266, H952-H958.
15. + channels in vasodilation induced by nitroglycerin, acetylcholine and nitric oxide. J Pharmac Exp Ther 267, 1327-1335.
16. G-Nitro-L-arginine-resistant endothelium-dependent relaxation induced by acetylcholine in the rabbit renal artery. Life Sci 55, 491-498.
17. Kitazono, T., Faraci, F.M., Taguchi, H., Heistad, D.D., 1995. Role of potassium channels in cerebral blood vessels. Stroke 26, 1713-1723.
18. Komori, K., Suzuki, H., 1987. Electrical responses of smooth muscle cells during cholinergic vasodilation in the rabbit saphenous artery. Circ Res 61, 586-593.
19. Komori, K., Lorenz, R., Vanhoutte, P.M., 1988. Nitric oxide, ACh and electrical and mechanical properties of canine arterial smooth muscle. Am J Physiol 255, H207-H212.
20. Marín, J., 1995. Age-related changes in vascular responses: a review. Mech. Ageing Dev 79, 71-114.
21. Marín, J., Rodríguez-Martínez, M.A., 1997. Role of vascular nitric oxide in physiological and pathological conditions. Pharmac Ther 75, 111-134.
22. Marín, J., Sánchez-Ferrer, C.F., 1990. Role of endothelium-formed nitric oxide on vascular responses. Gen Pharmac 21, 575-587.
23. Marín, J., Salaices, M., Gómez, B., Lluch, S., 1981. Noradrenergic component in the vasoconstriction induced by 5-hydroxytryptamine in goat cerebral arteries. J Pharm Pharmac 33, 715-719.
24. Moncada, S., Palmer, R.M.J., Higgs, E.A., 1991. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmac Rev 43, 109-142.
25. + channels mediate an endothelium-dependent hyperpolarization in rabbit mesenteric arteries. J Physiol 489, 723-734.
26. Nelson, M.T., Quayle, J.M., 1995. Physiological roles and properties of potassium channels in arterial smooth muscle. Am J Physiol 268, C799-C822.
27. Palmer, R.M.J., Ferrige, A.G., Moncada, S., 1987. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327, 524-526.
28. Plane, F., Garland, C.J., 1993. Differential effects of acetylcholine, nitric oxide and levocromakalim on smooth muscle membrane potential and tone in the rabbit basilar artery. Br J Pharmac 110, 651-656.
29. Plane, F., Pearson, T., Garland, C.J., 1995. Multiple pathways underlying endothelium-dependent relaxation in the rabbit isolated femoral artery. Br J Pharmac 115, 31-38.
30. + pump inhibitors and membrane depolarizing agents on acetylcholine-induced endothelium-dependent relaxation and cyclic GMP accumulation in rat aorta. Eur J Pharmac 110, 203-209.
31. Robertson, B.E., Schubert, R., Hescheler, J., Nelson, M.T., 1993. cGMP-dependent protein kinase activates Ca-activated K channels in cerebral artery smooth muscle cells. Am J Physiol 265, C299-C303.
32. + channels in arterial smooth muscle. Science 245, 177-180.
33. Suzuki, H., 1988. The electrogenic Na-K pump does not contribute to endothelium-dependent hyperpolarization in the rabbit ear artery. Eur J Pharmac 156, 295-297.
34. + ATPase in cyclic GMP-mediated relaxation of canine pulmonary artery smooth muscle cells. Br J Pharmac 122, 112-116.
35. + channels are stimulated by cyclic guanosine monophosphate-dependent protein kinase in canine coronary artery smooth muscle cells. Pfluegers Arch 423, 167-172.
36. Tare, M., Parkington, H.C., Coleman, H.A., Neild, T.O., Dusting, G.J., 1990. Hyperpolarization and relaxation of arterial smooth muscle caused by nitric oxide derived from the endothelium. Nature 346, 69-71.
37. Taylor, S.G., Weston, A.H., 1988. Endothelium-derived hyperpolarizing factor: a new endogenous inhibitor from the vascular endothelium. Trends Pharmac Sci 9, 272-274.
38. Vanheel, B., Van de Voorde, J., Leusen, I., 1994. Contribution of nitric oxide to the endothelium-dependent hyperpolarization in rat aorta. J Physiol 475, 277-284.
39. Xie, H., Triggle, C.R., 1994. Endothelium-independent relaxations to acetylcholine and A23187 in the human umbilical artery. J Vasc Res 31, 92-105.