Homogeneous genotyping assays for single nucleotide polymorphisms with fluorescence resonance energy transfer detection

Genetic Analysis - Biomolecular Engineering

Volumn 14, Issue 5-6, 1999, Pages 157-163

  Chen, Xiangning ^a   Kwok, Pui Yan ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

DNA ligase; DNA polymerase; Fluorescence resonance energy transfer; Oligonucleotide ligation; Primer extension; Single nucleotide polymorphism

Indexed keywords

CONFERENCE PAPER; DNA DETERMINATION; ESCHERICHIA COLI; FLUORESCENCE; GENE MUTATION; GENETIC POLYMORPHISM; GENOTYPE; MEDICAL GENETICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ANIMALS; DNA MUTATIONAL ANALYSIS; DNA PRIMERS; FISHES; FLUORESCENT DYES; GENOTYPE; HUMANS; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; SPECTROMETRY, FLUORESCENCE;

ESCHERICHIA COLI;

EID: 0033007317     PISSN: 10503862     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1050-3862(98)00016-3     Document Type: Conference Paper

References (17)

1. Cooper D.N., Smith B.A., Cooke H.J. An estimate of unique DNA sequence heterozygosity in the human genome. Hum. Genet. 69:1985;201-205.
2. Drmanac R., Drmanac S., Strezoska Z., Paunesku T., Labat I., Zeremski M. et al. DNA sequence determination by hybridization: a strategy for efficient large-scale sequencing. Science. 260:1993;1649-1652.
3. Livak K.J., Marmaro J., Todd J.A. Towards fully automated genome-wide polymorphism screening. Nat. Genet. 9:1995;341-342.
4. Tyagi S., Bratu D.P., Kramer F.R. Multicolor molecular beacons for allele discrimination. Nat. Biotechnol. 16:1998;49-53.
5. Whitcombe D., Brownie J., Gillard H.L, McKechnie D., Theaker J., Newton C.R., Little S. A homogeneous fluorescence assay for PCR amplicons: its application to real-time, single-tube genotyping. Clin. Chem. 44:1998;918-923.
6. Yershov G., Barsky V., Belgovskiy A., Kirillov E., Kreindlin E., Ivanov I. et al. DNA analysis and diagnostics on oligonucleotide microchips. Proc. Natl. Acad. Sci. USA. 93:1996;4913-4918.
7. Syvanen A.-C., AAlto-Setala K., Harju L., Kontula K., Soderlund H. A primer-guided nucleotide incorporation assay in the genotyping of apolipoprotein E. Genomics. 8:1990;684-692.
8. Landegren U., Kaiser R., Sanders J., Hood L. A ligase-mediated gene detection technique. Science. 241:1988;1077-1080.
9. Nickerson D.A., Kaiser R., Lappin S., Stewart J., Hood L., Landegren U. Automated DNA diagnostics using an ELISA-based oligonucleotide ligation assay. Proc. Natl. Acad. Sci. USA. 87:1990;8923-8927.
10. Pease A.C., Solas D., Sullivan E.J., Cronin M.T., Holmes C.P., Fodor S.P. Light-generated oligonucleotide arrays for rapid DNA sequence analysis. Proc. Natl. Acad. Sci. USA. 91:1994;5022-5026.
11. Chen X., Kwok P.Y. Template-directed dye-terminator incorporation (TDI) assay: a homogeneous DNA diagnostic method based on fluorescence resonance energy transfer. Nucleic Acids Res. 25:1997;347-353.
12. Chen X., Zehnbauer B., Gnirke A., Kwok P.Y. Fluorescence energy transfer detection as a homogeneous DNA diagnostic method. Proc. Natl. Acad. Sci. USA. 94:1997;10756-10761.
13. Foster, T. In: Sinanoglu O, editors. Morden quantum chemistry, Istanbul lectures, Part III. New York: Academic Press, 1965:93-137.
14. Chen X., Livak K.J., Kwok P.Y. A homogeneous, ligase-mediated DNA Diagnostic test. Genome Res. 8:1998;549-556.
15. Tabor S., Richardson C.C. A single residue in DNA polymerases of the Escherichia coli DNA polymerase I family is critical for distinguishing between deoxy- and dideoxyribonucleotides. Proc. Natl. Acad. Sci. USA. 92:1995;6339-6343.
16. Heighway J. BsmI polymorphism in N-ras intron I (RASN). Nucleic Acids Res. 19:1991;682.
17. Trecartin R.F., Liebhaber S.A., Chang J.C., Lee K.Y., Kan Y.W., Furbetta M., Angius A., Cao A. Beta-thalassemia in Sardinia is caused by nonsense mutation. J. Clin. Invest. 68:1981;1012-1017.