Cerebrovascular alterations in protein kinase C-mediated constriction in stroke-prone rats

Stroke

Volumn 30, Issue 3, 1999, Pages 656-661

  Smeda, John S ^a,b   King, Shelley ^a  

^a MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

^b MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

Author keywords

Cerebral arteries; Phorbol 12,13 dibutyrate; Protein kinase C; Rats; Stroke

Indexed keywords

BISINDOLYLMALEIMIDE; CHELERYTHRINE; NIFEDIPINE; PHORBOL DIBUTYRATE; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; STAUROSPORINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; ENZYME ACTIVATION; MALE; MIDDLE CEREBRAL ARTERY; NONHUMAN; PRIORITY JOURNAL; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; STROKE;

EID: 0033006973     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.30.3.656     Document Type: Article

References (22)

1. Johnson PC. Autoregulation of blood flow. Circ Res. 1986;59:483-495.
2. Harder DR. Pressure-dependent membrane depolarization in cat middle cerebral artery. Circ Res. 1984;55:197-202.
3. Harder DR, Gilbert R, Lombard JH. Vascular muscle cell depolarization and activation in renal arteries on elevation of transmural pressure. Am J Physiol. 1987;253:F778-F78.
4. Hayashi K, Epstein M, Loutzenhiser R. Pressure-induced vasoconstriction of renal microvessels in normotensive and hypertensive rats. Circ Res. 1989;65:1475-1484.
5. + channels in rabbit myogenic cerebral arteries. Am J Physiol. 1995;269:H348-H355.
6. Hill MA, Falcone JC, Meininger GA. Evidence for protein kinase C involvement in arteriolar myogenic reactivity. Am J Physiol. 1990;259: H1586-H1594.
7. Osol G, Laher I, Cipolla M. Protein kinase C modulates basal myogenic tone in resistance arteries from the cerebral circulation. Circ Res. 1991; 68:359-367.
8. Osol G. Protein kinase C activation lowers the calcium requirement for cerebral artery myogenic tone. In: Halpern W, Bevan J, Breton J, Dustman H, Nelson M, Osol G, eds. 4th International Symposium on Resistance Arteries, Tatoo, NJ: Humana Press Inc; 1994:1-12.
9. +2 influx. J Hypertens. 1989;7(suppl 4):S17-S20.
10. Smeda JS. Cerebral vascular changes associated with hemorrhagic stroke in hypertension. Can J Physiol Pharmacol. 1992;70:552-564.
11. Smeda JS. Hemorrhagic stroke development in spontaneously hypertensive rats fed a North American, Japanese-style diet. Stroke. 1989;20: 1212-1218.
12. Halpern W, Osol G, Coy GS. Mechanical behaviour of pressurized in vitro prearteriolar vessels determined with a video system. Ann Biomed Eng. 1984;12:463-469.
13. Fish DR, Sperti G, Colucci WS, Clapham DE. Phorbol ester increases the dihydropyridine-sensitive calcium conductance in a vascular smooth muscle cell line. Circ Res. 1988;62:1049-1054.
14. Laher I, Bevan JA. Protein kinase C activation selectively augments a stretch-induced, calcium-dependent tone in vascular smooth muscle. J Pharmacol Exp Ther. 1987;242:566-572.
15. Meininger GA, Zawieja DC, Falcone JC, Hill MA, Davey JP. Calcium measurement in isolated arterioles during myogenic and agonist stimulation. Am J Physiol. 1991;261:H950-H959.
16. 2+ sensitivity in pressurized rat cerebral arteries. Am J Physiol. 1998;274:H1920-H1927.
17. Osol G, Laher I, Kelly M. Myogenic tone is coupled to phospholipase C and G protein activation in small cerebral arteries. Am J Physiol. 1993; 265:H415-H420.
18. Narayanan J, Imig M, Roman RJ, Harder DR. Pressurization of isolated renal arteries increases inositol triphosphate and diacylglycerol. Am J Physiol. 1994;266: H1840-H1845.
19. Walsh MP, Andrea JE, Allen BG, Clément-Chomienne O. Smooth muscle protein kinase C. Can J Physiol Pharmacol. 1994;72: 1392-1399.
20. 1-vascular vasopressin receptors. Regul Pept. 1992;38:1-11.
21. Smeda JS, King S. Cerebrovascular alterations associated with stroke. FASEB J. 1996;10:A29. Abstract.
22. 2+] in cerebral arteries of rat by membrane potential and intravascular pressure. J Physiol (Lond). 1998;508:199-209.