The role of low resistance blood flow pathways in the pathogenesis and healing of venous leg ulcers

Acta Dermato-Venereologica

Volumn 79, Issue 2, 1999, Pages 156-160

  Malanin, Ken ^a,b,c   Kolari, Pertti J ^b   Havu, Väinö K ^a  

^a UNIVERSITY OF TURKU   (Finland)

^b SOUTH KARELIA CENTRAL HOSPITAL   (Finland)

^c NONE   (Finland)

Author keywords

Arteriovenous shunting; Chronic venous insufficiency; Doppler ultrasound; Intermittent pneumatic compression; Laser Doppler fluxmetry

Indexed keywords

ADULT; AGED; ARTERY RESISTANCE; ARTICLE; BLOOD FLOW VELOCITY; CLINICAL ARTICLE; COLOR ULTRASOUND FLOWMETRY; CUFF; FEMALE; HUMAN; LEG BLOOD FLOW; LEG COMPRESSION; LEG ULCER; MALE; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

EID: 0033006650     PISSN: 00015555     EISSN: None     Source Type: Journal    
DOI: 10.1080/000155599750011435     Document Type: Article

References (39)

1. Kolari PJ, Pekanmäki K, Pohjola RT. Transcutaneous oxygen tension in patients with post-thrombotic leg ulcers: treatment with intermittent pneumatic compression. Cardiovasc Res 1988; 22: 138-141.
2. Pekanmäki K, Kolari PJ, Kiistala U. Laser Doppler vasomotion among patients with post-thrombotic venous insufficiency: effect of intermittent pneumatic compression. VASA 1991; 20: 394-397.
3. Coleridge Smith P, Sarin S, Hasty J, Scurr JH. Sequential gradient pneumatic compression enhances venous ulcer healing: a randomized trial. Surgery 1990; 108: 871-875.
4. Rithalia SVS, Edwards J, Sayegh A. Effect of intermittent pneumatic compression on lower limb oxygenation. Arch Phys Med Rehabil 1988; 69: 665-667.
5. Partsch H. Hyperaemic hypoxia in venous ulceration. Br J Dermatol 1984; 110: 249-250.
6. 2 and laser Doppler blood flow measurements in 40 patients with venous leg ulcers. Acta Derm Venereol (Stockh) 1987; 67: 160-182.
7. Cheatle TR, Stibe ECL, Shami SK, Scurr JH, Coleridge Smith PD. Vasodilatory capacity of the skin in venous disease and its relationship to transcutaneous oxygen tension. Br J Surg 1991; 78: 607-610.
8. Svedman C, Cherry GW, Ryan TJ. The veno-arteriolar reflex in venous leg ulcer patients studied by laser Doppler imaging. Acta Derm Venereol (Stockh) 1998; 78: 258-261.
9. Pryce DW, Friedmann PS. Hemodynamics of leg ulceration assessed by laser Doppler flowmetry. J Am Acad Dermatol 1993; 29: 708-714.
10. Malanin K, Kolari PJ, Haapanen A, Helander I, Havu VK. Cutaneous blood flow in legs with severe chronic venous insufficiency recorded before and after a single treatment using intermittent pneumatic compression. Phlebology 1996; 11: 30-33.
11. Fagrell B. Local microcirculation in chronic venous incompetence and leg ulcers. Vasc Surg 1979; 13: 217-225.
12. Wenner A, Leu HJ, Spycher M, Brunner U. Ultrastructural changes of capillaries in chronic venous insufficiency. Expl Cell Biol 1980; 48: 1-14.
13. Franzeck UK, Bollinger A, Huch R, Huch A. Transcutaneous oxygen tension and capillary morphologic characteristics and density in patients with chronic venous incompetence. Circulation 1984; 70: 806-811.
14. Creutzig A, Caspary L, Alexander K. Changes of skin microcirculation in patients with chronic venous insufficiency assessed by laser Doppler fluxmetry and transcutaneous oxymetry. Phlebology 1994; 9: 158-163.
15. Hopkins NFG, Spinks TJ, Rhodes CG, Ranicar ASO, Jamieson CW. Positron emission tomography in venous ulceration and liposclerosis: study of regional tissue function. BMJ 1983; 286: 333-336.
16. Fontaine R. The John Homans Memorial lecture. Remarks concerning venous thrombosis and its sequelae. Surgery 1957; 41: 6-25.
17. Haimovici H, Steinman C, Caplan LH. Role of arteriovenous anastomoses in vascular diseases of the lower extremity. Ann Surg 1966; 164; 990-1002.
18. Schalin L. Arteriovenous communication to varicose veins in the lower extremities studied by dynamic angiography. Acta Chir Scand 1980; 146: 397-406.
19. Blalock A. Oxygen content of blood in patients with varicose veins. Arch Surg 1929; 19: 898-905.
20. Lofferer O, Mostbeck A, Partsch II. Arteriovenöse Kurzschlusse der Extremitäten. Nuclearmedizinische Untersuchungen mit besonderer Berucksichtigung des postthrombotischen Unterschenkelgeschwurs. Zentralbl Phlebol 1969; 8: 2-22.
21. Hehne HJ, Locher JT, Waibel PP, Fridrich R. Zur Bedeutung arteriovenöser Anastomosen bei der primären Varicosis und der chronisch-venösen Insuffizienz. Vasa 1974; 3: 396-398.
22. Malanin K, Haapanen A, Havu V. Lowered peripheral resistance in arteries of legs with venous ulcer. Acta Derm Venereol (Stockh) 1994; 74: 110-112.
23. Malanin K, Haapanen A, Kolari PJ, Helander I, Havu VK. The peripheral resistance in arteries of legs is inversely proportional to the severity of chronic venous insufficiency. Acta Derm Venereol (Stockh) 1997; 77: 22-25.
24. Dormandy JA. Pathophysiology of venous leg ulceration. Angiology 1997; 48: 71-75.
25. Carter SA. Indirect systolic pressures and pulse waves in arterial occlusive disease of the lower extremities. Circulation 1968; 37: 624-637.
26. The Venous forum of the Royal Society of Medicine and Societas Phlebologica Scandinavica. Classification and grading of chronic venous disease in the lower limbs: a consensus statement. Phlebology 1995; 10: 42-45.
27. Nilsson GE, Tenland T, Öberg PǍ. Evaluation of a laser Doppler flowmeter for measurement of tissue blood flow. IEEE Trans Biomed Eng 1980; 27: 597-604.
28. Bircher A, De Boer EM, Agner T, Wahlberg JE, Serup J. Guidelines for measurement of cutaneous blood flow by laser Doppler flowmetry. A Report from the Standardization Group of the European Society of Contact Dermatitis. Contact Dermatitis 1994; 30: 65-72.
29. Pekanmäki K, Kolari PJ. Sequential and graded intermittent pneumatic compression device for treatment of swollen limbs. Biomed Technik 1987; 32: 50-54.
30. Stranden E. A comparison between surface measurements and water displacement volumetry for the quantification of leg edema. J Oslo City Hosp 1981; 31: 153-155.
31. Kolari PJ. Penetration of unfocused laser light into the skin. Arch Dermatol Res 1985; 277: 342-344.
32. Gniadecka M. Localization of dermal edema in lipodermatosclerosis, lymphedema and cardiac insufficiency. J Am Acad Dermatol 1996; 35: 37-41.
33. Belcaro GV, Nicolaides AN. Acute effects of intermittent sequential compression in venous hypertension. J Cardiovasc Surg 1993; 34: 493-497.
34. Ryan TJ, Burnand K. Diseases of the veins and arteries leg ulcers. In: Textbook of dermatology. vol. 6, part 3. Champion RH, Burton JL, Burns DA, Breatnach SM, eds. Oxford: Blackwell Scientific Publications, 1998: 2227-2275.
35. Partsch H. Investigations on the pathogenesis of venous leg ulcers. Acta Chir Scand Suppl. 1988; 554: 25-29.
36. Stigall KE, Dorsey JS. Late complications of traumatic arteriovenous fistula. Am Surg 1989; 55: 180-183.
37. Brakman M, Faber WR, Zeegelaar JE, Bousema MT, van Proosdij JL, Kerckhaert JAM. Venous hypertension of the hand caused by hemodialysis shunt: immunofluorescence studies of pericapillary cuffs. J Am Acad Dermatol 1994; 31: 23-26.
38. Jörneskog G, Fagrell B. Discrepancy in skin capillary circulation between fingers and toes in patients with type 1 diabetes. Int J Microcirc 1996; 16: 313-319.
39. Welbourn E. The value of radiological investigation of chronic stasis ulcers of the leg. Clin Radiol 1967; 18: 372-378.