Familial factors influence level of functioning in pervasive developmental disorder

Journal of the American Academy of Child and Adolescent Psychiatry

Volumn 38, Issue 6, 1999, Pages 746-753

  MacLean, Joanna E ^a   Szatmari, Peter ^a,e   Jones, Marshall B ^d   Bryson, Susan E ^c   Mahoney, William J ^b   Bartolucci, Giampiero ^a   Tuff, Lawrence ^a  

^a Department of Psychiatry ^*  (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c YORK UNIVERSITY   (Canada)

^d PENN STATE COLLEGE OF MEDICINE   (United States)

^e HAMILTON HEALTH SCIENCES   (Canada)

Author keywords

Asperger's disorder; Autism; Genetics

Indexed keywords

ADAPTIVE BEHAVIOR; ADOLESCENT; ADULT; ARTICLE; ASPERGER SYNDROME; AUTISM; CHILD; COMMUNICATION DISORDER; FAMILY; FEMALE; HUMAN; INTELLIGENCE QUOTIENT; MAJOR CLINICAL STUDY; MALE; NONVERBAL COMMUNICATION; PRIORITY JOURNAL; SIBLING; SOCIAL BEHAVIOR;

EID: 0033006510     PISSN: 08908567     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004583-199906000-00023     Document Type: Article

References (35)

1. American Psychiatric Association (1994), Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV). Washington, DC: American Psychiatric Association, pp 66-72
2. Bailey A, Le Couteur A, Gottesman I et al. (1995). Autism as a strongly genetic disorder: evidence from a British twin study. Psychol Med 25:63-77
3. Bryson SE, Clark BS, Smith IM (1988), First report of a Canadian epidemiological study of autistic syndromes. J Child Psychol Psychiatry 29:433-445
4. Burke JG, Murphy BM, Bray JC, Walsh D, Kendler KS (1996), Clinical similarities in siblings with schizophrenia. Am J Med Genet 67:239-243
5. Cicchetti DV, Sparrow SS (1981), Developing criteria for establishing interrater reliability of specific items in a given inventory. Am J Ment Defic 86:127-137
6. Cook EH Jr, Courchesne R, Lord C et al. (1997), Evidence of linkage between the serotonin transporter and autistic disorder. Mol Psychiatry 2:247-250
7. Ehlers S, Gillberg C (1993), The epidemiology of Asperger syndrome: a total population study. J Autism Dev Disord 34:1327-1350
8. Holstein S, Rutter M (1977), Infantile autism: a genetic study of 21 twin pairs. J Child Psychol Psychiatry 18:297-321
9. Folstein S, Rutter M (1991), Family History Interview for Developmental Disorders of Cognition and Social Functioning (available from authors)
10. Fombonne E, Bolton P, Prior J, Jordon H, Rutter M (1997), A family study of autism: cognitive patterns and levels in parents and siblings. J Child Psychol Psychiatry 38:667-683
11. Gonez-Isla T, West HL, Rebek GW et al. (1996), Clinical and pathological correlates of apolipoprotein E epsilon 4 in Alzheimer's disease. Ann Neurol 39:62-70
12. Haggard EA (1958), Intraclass Correlation and the Analysis of Variance. New York: Dryden Press, pp 10-16
13. International Molecular Genetic Study of Autism Consortium (1998), A full genome screen for autism with evidence for linkage to a region on chromosome 7q. Hum Mol Genet 7:571-578
14. Kendler KS, Karkowski-Shuman L, O'Neill FA, Straub RE, MacLean CJ, Walsh D (1997), Resemblance of psychotic symptoms and syndromes in affected sibling pairs from the Irish Study of High-Density Schizophrenia Families: evidence for possible etiologic heterogeneity. Am J Psychiatry 154:191-198
15. Klauk SM, Poustka BA, Lesch KP, Poustka A (1997), Serotonin transporter (5-HTT) gene variants associated with autism? Hum Mol Genet 6:2233-2238
16. Le Couteur A, Bailey A, Goode S et al. (1996), A broader phenotype of autism: the clinical spectrum in twins. J Child Psychol Psychiatry 37:785-801
17. Le Couteur A, Rutter M, Lord C et al. (1989), Autism Diagnostic Interview a standardized investigator-based interview. J Autism Dev Disord 19:363-387
18. Lord C, Rutter M, Goode S et al. (1989), Autism Diagnostic Observation Schedule: a standardized observation of communication and social behavior. J Autism Dev Disord 19:185-212
19. Lord C, Rutter M, Le Couteur A (1994), Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorder. J Autism Dev Disord 24:659-685
20. Mahoney WJ, Szatmari P, MacLean JE et al. (1998), Reliability and accuracy of differentiating pervasive developmental disorder subtypes. J Am Acad Child Adolesc Psychiatry 37:278-285
21. Miller JN, Ozonoff S (1997), Did Asperger's cases have Asperger disorder? A research note. J Child Psychol Psychiatry 38:247-251
22. Narod SA, Ford D, Devilee P et al. and the Breast Cancer Linkage Consortium (1995), An evaluation of genetic heterogeneity in 145 breast-ovarian cancer families. Am J Hum Genet 56:254-264
23. Pickles A, Bolton P, Macdonald H et al. (1995), Latent-class analysis of recurrence risks for complex phenotypes with selection and measurement error: a twin and family history study of autism. Am J Hum Genet 57:717-726
24. Ritvo ER, Freeman BJ, Mason-Brothers A, Mo A, Ritvo AM (1985), Concordance for the syndrome of autism in 40 pairs of afflicted twins. Am J Psychiatry 142:74-77
25. Shen MH, Harper BS, Upadhyaya M (1996), Molecular genetics of neurofibromatosis type I (NFI). J Med Genet 33:2-17
26. Sparrow SS, Balla D, Cicchetti D (1984), Vineland Adaptive Behavior Scales (Survey Form). Circles Pines, MN: American Guidance Service
27. Spiker D, Lotspeich L, Kraemer HC et al. (1994), Genetics of autism: characteristics of affected and unaffected children from 37 multiplex families. Am J Med Genet 54:27-35
28. Steffenburg S, Gillberg C, Hellgren L et al. (1989), A twin study of autism in Denmark, Finland, Iceland, Norway and Sweden. J Child Psychol Psychiatry 30:405-416
29. Szatmari P, Archer L, Fisman S, Streiner DL, Wilson FJ (1995), Asperger's syndrome and autism: differences in behavior, cognition and adaptive functioning. J Am Acad Child Adolesc Psychiatry 34:1662-1671
30. Szatmari P, Bryson SE, Streiner DL, Wilson FJ, Ryerse C (1997), The two-year outcome of preschool children with autism and Asperger syndrome. Presented at the annual meeting of the American Academy of Child and Adolescent Psychiatry, Toronto, October
31. Szatmari P, Jones MB (1991), IQ and the genetics of autism. J Child Psychol Psychiatry 32:897-908
32. Szatmari P, Jones MB, Holden J et al. (1996), High phenotypic correlations among siblings with autism and pervasive developmental disorders (PDD). Am J Med Genet 67:354-360
33. Szatmari P, Jones MB, Tuff LP, Bartolucci G, Fisman S, Mahoney WJ (1993), Lack of cognitive impairment in first-degree relatives of children with pervasive developmental disorders. J Am Acad Child Adolesc Psychiatry 32:1264-1273
34. Szatmari P, Jones MB, Zwaigenbaum L, MacLean JE (1998), The genetics of autism: an overview and new directions. J Autism Dev Disord 28:351-368
35. Volkmar FR, Sparrow SS, Goudreau D, Cicchetti D, Paul R, Cohen DJ (1987), Social deficits in autism: an operational approach using the Vineland Adaptive Behavior Scales. J Am Acad Child Adolesc Psychiatry 26:156-161