CD4 segregates into specific detergent-resistant T-cell membrane microdomains

Tissue Antigens

Volumn 53, Issue 1, 1999, Pages 33-40

  Millan J ^a   Cerny, J ^b   Horejsi, V ^b   Alonso, Miguel A ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

Author keywords

CD4; Detergent insoluble membranes; Glycolipids; Glycosylphosphatidylinositol anchored proteins; Src like tyrosine kinases

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; T LYMPHOCYTE RECEPTOR;

ARTICLE; LYMPHOCYTE MEMBRANE; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMALS; ANTIGENS, CD3; ANTIGENS, CD4; ANTIGENS, CD59; CD4-POSITIVE T-LYMPHOCYTES; CELL FRACTIONATION; CELL MEMBRANE; DETERGENTS; GLYCOLIPIDS; GLYCOSYLPHOSPHATIDYLINOSITOLS; HUMANS; LEUKEMIA, T-CELL, ACUTE; LYMPHOCYTE ACTIVATION; MEMBRANE LIPIDS; MEMBRANE PROTEINS; MICE; OCTOXYNOL; PROTEIN KINASES; RECEPTORS, ANTIGEN, T-CELL; SOLUBILITY; TUMOR CELLS, CULTURED;

EID: 0033005749     PISSN: 00012815     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-0039.1999.530104.x     Document Type: Article

References (27)

1. 1. Stefanova I, Horejsi V, Ansotegu I, Knapp W, Stockinger H. GPI-anchored cell-surface molecules complexed to protein tyrosine kinases. Science 1991: 254: 1016-9.
2. 2. Cinek T, Horejsi V. The nature of large noncovalent complexes containing glycosylphosphatidylinositol-anchored membrane glycoproteins and protein tyrosine kinases. J Immunol 1992: 146: 4092-8.
3. 3. Hanada I, Nishijima M, Akamatsu Y, Pagano RE. Both sphingolipids and cholesterol participate in the detergent insolubility of alkaline phosphatase, a glycosylphosphatidylinositol-anchored protein, in mammalian membranes. J Biol Chem 1995: 270: 6254-60.
4. 4. Salomon KR, Rudd CE, Finberg RW. The association between glycosylphosphatidylinositol-anchored proteins and heterotrimeric G protein α subunits in lymphocytes. Proc Natl Acad Sci U S A 1996: 93: 6053-8.
5. 5. Brown D. The tyrosine kinase connection: how GPI-anchored proteins activate T cells. Curr Opin Immunol 1993: 5: 349-54.
6. 6. Korty PE, Brando C., Shevach EM. CD59 functions as a signal-transducing molecule for human T cell activation. J Immunol 1991: 146: 4092-8.
7. fyn. J Immunol 1992: 149: 3535-41.
8. 8. Decker M, Ticchioni M, Mari B, Mari D, Bernard A. The glycosyl-phosphatidylinositol-anchored CD59 protein stimulates both T cell receptor ζ/ZAP-70-dependent and -independent signaling pathways in T cells. Eur J Immunol 1995: 25: 1815-22.
9. 9. Robinson PJ. Phosphatidylinositol membrane anchors and T-cell activation. Immunol Today 1991: 12: 35-41.
10. 10. Arni S, Ilangumaran S, van Echten-Deckert G et al. Differential regulation of Src family protein tyrosine kinases in GPI domains of T lymphocyte plasma membranes. Biochem Biophys Res Commun 1996: 225: 801-7.
11. 11. Cinek T, Hilgert I, Horejsi V. An alternative way of CD4 and CD8 association with protein kinases of the Src family. Immunogenetics 1995: 41: 110-6.
12. 12. Parolini I, Sargiacomo M, Lisanti MP, Peschle C. Signal transduction and glycosylphosphatidylinositol-linked proteins (Lyn, Lck, CD4, CD45, G proteins, and CD55) selectively localize in Triton-insoluble plasma membrane domains of human leukemic cell lines and normal granulocytes. Blood 1996: 87: 3783-94.
13. lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs. Cell 1990: 60: 755-65.
14. 14. Littman DR. The CD4 Molecule. Berlin: Springer-Verlag, 1996.
15. 15. Brown DA, Rose JK. Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface. Cell 1992: 68: 533-44.
16. 16. Schnitzer JE, McIntosh DP, Dvorak AM, Liu J, Oh P. Separation of caveolae from associated microdomains of GPI-anchored proteins. Science 1995: 269: 1435-9.
17. 17. Bohuslav J, Horejsi V, Hansmann C et al. Urokinase plasminogen activator receptor β2-integrins, and Src-kinases within a single receptor complex of human monocytes. J Exp Med 1995: 181: 1381-90.
18. 18. Millán J, Puertollano R, Fan L, Alonso MA. Caveolin and MAL, two protein components of internal detergent-insoluble membranes, are in distinct lipid microenvironments in MDCK cells. Biochem Biophys Res Commun 1997: 233: 707-12.
19. 19. Ilangumaran S, Briol A, Hoessli DC. Distinct interactions among GPI-anchored, transmembrane and membrane associated intracellular proteins, and sphingolipids in lymphocyte and endothelial cell plasma membranes. Biochim Biophys Acta 1997: 1328: 227-36.
20. lck. Cell 1988: 55: 301-8.
21. 21. Tamura GS, Dailey MO, Gallatin WM, McGrath MS, Weismann IL, Pillemer EA. Isolation of molecules recognized by monoclonal antibodies and antisera: the solid phase immunoisolation technique. Anal Biochem 1984: 136: 458-64.
22. 22. Kypta RM, Goldberg Y, Ulug ET, Courtneidge SA. Association between the PDGF receptor and members of the Src family of tyrosine kinases. Cell 1990: 62: 481-91.
23. 23. Brown DA. Interactions between GPI-anchored proteins and membrane lipids. Trends Cell Biol 1992: 2: 338-43.
24. 24. Xavier R, Brennan T, Li Q, McComack C, Seed B. Membrane compartmentation is required for efficient T cell activation. Immunity 1998: 8: 723-32.
25. 25. Montixi C, Langlet C, Bernard A-M et al. Engagement of T cell receptor triggers its recruitment to low density detergent-insoluble membrane domains. EMBO J 1998: 17: 5334-48.
26. 26. Cerny J, Stockinger H, Horejsi V. Noncovalent associations of T lymphocyte surface proteins. Eur J Immunol 1996: 26: 2335-43.
27. 27. Harder T, Scheiffele P, Verkade P, Simons K. Lipid domain structure of the plasma membrane revealed by patching of membrane components. J Cell Biol 1998: 141: 929-42.