Effect of a 14-day hindlimb suspension on β-adrenoreceptors in rats

Comparative Biochemistry and Physiology - C Pharmacology Toxicology and Endocrinology

Volumn 123, Issue 1, 1999, Pages 95-102

  Bouzeghrane, F ^a,b   Somody, L ^b   Gallo Bona, N ^b   Gauquelin Koch, G ^b   Gharib, C ^b   Fagette, S ^b  

^a UNIVERSITY OF SCIENCES AND TECHNOLOGY HOUARI BOUMEDIENE   (Algeria)

^b UNIVERSITÉ LYON 1   (France)

Author keywords

adrenoreceptors; Affinity constant; Maximal binding capacity; Restraint; Simulated weightlessness

Indexed keywords

BETA ADRENERGIC RECEPTOR; CYANOPINDOLOL; PROPRANOLOL;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXERCISE; HEART; HEART ATRIUM; HEART VENTRICLE; HINDLIMB; IMMOBILIZATION; KIDNEY; MALE; MICROGRAVITY; NONHUMAN; PRIORITY JOURNAL; RAT; SIMULATION; WEIGHTLESSNESS;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; HEART ATRIA; HEART VENTRICLES; HINDLIMB SUSPENSION; KIDNEY; MALE; PINDOLOL; PROTEIN BINDING; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, BETA;

EID: 0033005635     PISSN: 07428413     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0742-8413(99)00015-8     Document Type: Article

References (28)

1. Bouzeghrane F., Fagette S., Somody L., Allevard A.M., Gharib C., Gauquelin G. Restraint vs. hindlimb suspension on fluid and electrolyte balance in rats. J Appl Physiol. 80:1996;1993-2001.
2. Bungo M.W., Charles J.B., Johnson P.C. Cardiovascular deconditioning during space flight and the use of saline as a countermeasure to orthostatic intolerance. Aviat Space Environ Med. 56:1985;985-990.
3. Charles J.B., Bungo M.W. Cardiovascular physiology in space flight. Exp Gerontol. 26:1991;163-168.
4. Chen J., Jin J., Ding Z., Zhang L. A modified tail-suspension model for simulating long-term weightlessness. Chin J Space Sci. 13:1993;159-162.
5. Convertino V.A., Polet J.L., Engelke K.A., Hoffler G.W., Lane L.D., Gunnar C. Evidence for increased β-adrenoreceptor responsiveness induced by 14 days of simulated microgravity in humans. Am J Physiol. 273:1997;93-99.
6. Cottet-Emard J.M., Pequignot J.M., Guëll A., Peyrin L., Gharib C. Catecholamines during short- and long-term head-down bed rest. Physiologist. 33 Suppl. 1:1990;S69-S72.
7. Fagette S., Fareh J., Cottet-Emard J.M., Pequignot J.M., Gauquelin G., Gharib C. Effects of short term hindlimb suspension on central and peripheral norepinephrine turnover in rats. Life Sci. 53:1993;555-561.
8. Fagette S., Lo M., Gharib C., Gauquelin G. Sympathetic nervous activity and cardiovascular variability after a 3-day tail suspension in rats. Eur J Appl Physiol. 69:1994;480-487.
9. Fagette S., Somody L., Bouzeghrane F., Cottet-Emard J.M., Gharib C., Gauquelin G. Central and peripheral sympathetic activities in rats during recovery from simulated weightlessness. J Appl Physiol. 79:1995;1991-1997.
10. Fareh J., Fagette S., Cottet-Emard J.M., Allevard A.M., Viso M., Gauquelin G. Comparison of the effects of spaceflight and hindlimb suspension on rat pituitary vasopressin and brainstem norepinephrine content. Adv Space Res. 14:1994;365-371.
11. Funk D., Stewart J. Role of catecholamines in the frontal cortex in the modulation of basal and stress-induced autonomic output in rats. Brain Res. 741(1-2):1996;220-229.
12. Gharib C., Maillet A., Gauquelin G., Allevard A.M., Güell A., Arbeille Ph. Results of 4-week head-down tilt with and without LBNP countermeasure. I. Volume regulating hormones. Aviat Space Environ Med. 63:1992;3-8.
13. Hellriegel E.T., D'mello A.P. The effect of acute, chronic and chronic intermittent stress on the central adrenergic system. Pharmacol Biochem Behav. 57:1997;207-214.
14. Leach C.S., Altchuler S.I., Cintron-Trevino N.M. The endocrine and metabolic response to space flight. Med Sci Sports Exerc. 15:1983;432-440.
15. Lee K., Miwa S., Fujiwara M., Magaribuchi T., Fujiwara M. Differential effects of hypoxia on the turnover of norepinephrine and epinephrine on the heart, adrenal gland, submaxillary gland and stomach. J Pharmacol Exp Ther. 240:1987;954-958.
16. Lundberg U. Catecholamine and cortisol excretion under physiogically different laboratory conditions. Usdin E., Kvetnansky R., Kopin J. Catecholamines and stress: recent advances. 1980;Elsevier, New York.
17. Maass H., Transmontano J., Baisch F. Response of adrenergic receptors to 10 days head-down tilt bedrest. Acta Physiol Scand. 144(S604):1992;61-68.
18. Martel E., Ponchon P., Champeroux P., Elghozi J.L., Renaud de la Faverie J.F., Dabire H., Pannier B., Richard S., Safar M., Cuche J.L. Mechanism of the cardiovascular deconditioning induced by tail suspension in the rat. Am J Physiol Heart Circ Physiol. 274(43):1998;H1667-H1673.
19. Mekaouche M., Siaud P., Givalois L., Barbanel G., Malaval F., Maurel D., Assenmacher I., Ixart G. Different responses of plasma ACTH and corticosterone and of plasma interleukin-1β to single and recurrent endotoxin challenges. J Leukocyte Biol. 59(3):1996;341-346.
20. Morey E.R. Spaceflight and bone turnover correlation with a new rat model of weightlessness. Bioscience. 29:1979;168-172.
21. Pardini B.J., Lund D.D., Schmid P.G. Organisation of the sympathetic post-ganglionic innervation of the rat heart. J Auton Nerv Syst. 28:1989;193-202.
22. Robertson D., Convertino V.A., Vernikos J. The sympathetic nervous system and the physiologic consequences of spaceflight: a hypothesis. Am J Med Sci. 308:1994;126-132.
23. Sautel M., Sacquet J., Vincent M., Sassard J. NE turnover in genetically hypertensive rats of Lyon strain. II. Peripheral organs. Am Physiol. 255:1988;H736-H741.
24. Scatchard G. The attraction of proteins for small molecules and ions. Ann NY Acad Sci. 51:1949;660-672.
25. Spector T. Refinement of Coomassie blue method of protein quantification. Anal Biochem. 86:1978;142-146.
26. Tucker B.J., Mundy C.A., Ziegler M.G., Baylis C., Blantz R.C. Head-down tilt and restraint on renal function and glomerular dynamics in the rat. J Appl Physiol. 63(2):1987;505-513.
27. Whitson P.A., Charles J.B., Williams W.J., Cintron N.M. Changes in sympathoadrenal response to standing in humans after spaceflight. J Appl Physiol. 79:1995;428-433.
28. Woodman C.R., Stump C.S., Stump J.A., Sebastian L.A., Rahman Z., Tipton C.M. Influences of chemical sympathectomy and simulated weightlessness on male and female rats. J Appl Physiol. 71(3):1991;1005-1014.