Both D-cis- and L-cis-diltiazem attenuate hydrogen peroxide-induced derangements in rat hearts

European Journal of Pharmacology

Volumn 374, Issue 3, 1999, Pages 387-398

  Xiao, Chun Yang ^a   Hara, Akiyoshi ^a   Hashizume, Hiroko ^a   Tanaka, Kunio ^a   Abiko, Yasushi ^a  

^a ASAHIKAWA MEDICAL COLLEGE   (Japan)

Author keywords

D cis Diltiazem; Energy metabolism; Hydrogen peroxide; L cis Diltiazem; Na+, intracellular; NMR (Nuclear magnetic resonance)

Indexed keywords

DILTIAZEM; HYDROGEN PEROXIDE; LACTATE DEHYDROGENASE; TETRODOTOXIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CIS ISOMER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENERGY METABOLISM; HEART HEMODYNAMICS; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MUSCLE CELL; ISOLATED HEART; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; RAT; SODIUM CELL LEVEL; STEREOSPECIFICITY;

ANIMALS; BUFFERS; CALCIUM CHANNEL BLOCKERS; DILTIAZEM; FREE RADICAL SCAVENGERS; HEART; HYDROGEN PEROXIDE; MALE; MYOCARDIUM; OXIDANTS; RATS; RATS, SPRAGUE-DAWLEY; SODIUM; SOLUTIONS; STEREOISOMERISM; TETRODOTOXIN;

EID: 0033005474     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00332-5     Document Type: Article

References (35)

1. Askenasy N., Tassini M., Vivi A., Navon G. Intracellular volume measurement and detection of edema: multinuclear NMR studies of intact rat hearts during normothermic ischemia. Magn. Reson. Med. 33:1995;515-520.
2. Banerjee A., Grosso M.A., Brown J.M., Rogers K.B., Whitman G.J.R. Oxygen metabolite effects on creatine kinase and cardiac energetics after reperfusion. Am. J. Physiol. 261:1991;H590-H597.
3. Bergmeyer, H.U., 1974a. Methods of Enzymatic Analysis. Academic Press, New York, pp. 1777-1781, 2101-2110, 2127-2131.
4. Bergmeyer, H.U., 1974b. Methods of Enzymatic Analysis. Academic Press, New York, pp. 574-579.
5. Bhatnagar A., Srivastava S.K., Szabo G. Oxidative stress alters specific membrane currents in isolated cardiac myocytes. Circ. Res. 67:1990;535-549.
6. Brown J.M., Terada L.S., Grosso M.A., Whitmann G.J., Velasco S.E., Patt A., Harken A.H., Repine J.E. Xanthine oxidase produces hydrogen peroxide which contributes to reperfusion injury of ischemic, isolated, perfused rat hearts. J. Clin. Invest. 81:1988;1297-1301.
7. + shift agent for perfused rat hearts Magn. Reson. Med. 15:1990;25-32.
8. Duff H.J., Sheldon R.S., Cannon N.J. Tetrodotoxin: sodium channel specific anti-arrhythmic activity. Cardiovasc. Res. 22:1988;800-807.
9. Fisher, A.B., 1988. Intracellular production of oxygen-derived free radicals. In: Halliwell, B. (Eds.), Oxygen Radicals and Tissue Injury. The Upjohn, Bethesda, pp. 9034-9039.
10. 2+ exchange in ventricular myocytes. Am. J. Physiol. 271:1996;H823-H833.
11. Hara A., Abiko Y. Protective effects of dilazep and its novel derivative, K-7259, on mechanical and metabolic derangements induced by hydrogen peroxide in the isolated perfused rat heart. J. Pharmacol. Exp. Ther. 277:1996;565-571.
12. Hara A., Matsumura H., Abiko Y. Lidocaine attenuates both mechanical and metabolic changes induced by hydrogen peroxide in the rat heart. Am. J. Physiol. 265:1993;H1478-H1485.
13. + exchanger attenuates the hydrogen peroxide-induced derangements in isolated perfused rat heart. Naunyn-Schmiedeberg's Arch. Pharmacol. 358:1998;R615. Suppl. 2.
14. Hayashi H., Yoshida H., Hashimoto F., Okazeri S. Changes in polyamine-oxidizing capacity of peroxisomes under various physiological conditions in rats. Biochim. Biophys. Acta. 991:1989;310-316.
15. Hess M.L., Manson N.H. Molecular oxygen: friend and foe. The role of the oxygen free radical system in the calcium paradox, the oxygen paradox and ischemia/reperfusion injury. J. Mol. Cell Cardiol. 16:1984;969-985.
16. Itogawa E., Kurosawa H., Yabana H., Murata S. Protective effect of L-cis-diltiazem on hypercontracture of rat myocytes induced by veratridine. Eur. J. Pharmacol. 317:1996;401-406.
17. Jabr R.I., Cole W.C. Oxygen derived free radical stress activates nonselective cation current in guinea pig ventricular myocytes: role of sulfhydryl groups. Circ. Res. 76:1995;812-824.
18. 2 concentrations and severity of acute lung injury. J. Appl. Physiol. 59:1985;1995-1998.
19. Janero D.R., Burghardt B., Lopez R. Protection of cardiac membrane phospholipid against oxidative injury by calcium antagonists. Biochem. Pharmacol. 37:1988;4197-4203.
20. 2+ paradox damage in rat hearts. Am. J. Physiol. 274:1998;H846-H852.
21. Kokita N., Hara A. Propofol attenuates hydrogen peroxide-induced mechanical and metabolic derangements in the isolated rat heart. Anesthesiology. 84:1996;117-127.
22. Loesser K.E., Kukreja R.C., Kazziha S.Y., Jesse R.L., Hess M.L. Oxidative damage to the myocardium: a fundamental mechanism of myocardial injury. Cardioscience. 2:1991;199-216.
23. Lucchesi B.R. Myocardial ischemia, reperfusion and free radical injury. Am. J. Cardiol. 65:1990;14I-23I.
24. Mak I.T., Weglicki W.B. Comparative antioxidant activities of propranolol, nifedipine, verapamil, and diltiazem against sarcolemmal membrane lipid peroxidation. Circ. Res. 66:1990;1449-1452.
25. Nagy A., Sellei P., Valen G., Sjöquist P.-O., Vaage J. Effects of a novel low-molecular weight antioxidant on cardiac injury induced by hydrogen peroxide. Free Radical Biol. Med. 20:1996;567-572.
26. Nakajima H., Hoshiyama M., Yamashita K., Kiyomoto A. Effect of diltiazem on electrical and mechanical activity of isolated cardiac ventricular muscle of guinea pig. Jpn. J. Pharmacol. 25:1975;383-392.
27. Nakaya H., Tohse N., Kanno M. Electrophysiological derangements induced by lipid peroxidation in cardiac tissue. Am. J. Physiol. 253:1987;H1089-H1097.
28. Nasa Y., Ichihara K., Abiko Y. Both D-cis- and L-cis-diltiazem have anti-ischemic action in the isolated, perfused working rat heart. J. Pharmacol. Exp. Ther. 255:1990;680-689.
29. Nasa Y., Ichihara K., Yoshida R., Abiko Y. Positive inotropic and negative chronotropic effects of (-)-cis-diltiazem in rat isolated atria. Br. J. Pharmacol. 255:1992;696-702.
30. + during myocardial ischemia: consequences for post-ischemic recovery. J. Mol. Cell Cardiol. 29:1997;85-96.
31. Ver Donck L., Borgers M. Myocardial protection by R 56865: a new principle based on prevention of ion channel pathology. Am. J. Physiol. 261:1991;H1828-H1835.
32. Ward C.A., Giles W.R. Ionic mechanism of the effects of hydrogen peroxide in rat ventricular myocytes. J. Physiol. 500:1997;631-642.
33. Weglicki W.B., Mak I.T., Simic M.G. Mechanisms of cardiovascular drugs as antioxidants. J. Mol. Cell Cardiol. 22:1990;1199-1208.
34. Xiao C.Y., Chen M., Hara A., Hashizume H., Abiko Y. Palmitoyl-L-carnitine modifies the myocardial levels of high-energy phosphates and free fatty acids. Basic Res. Cardiol. 92:1997;320-330.
35. Yanagida S., Luo C.S., Doyle M., Pohost G.M., Pike M.M. Nuclear magnetic resonance studies of cationic and energetic alterations with oxidant stress in the perfused heart. Modulation with pyruvate and lactate. Circ. Res. 77:1995;773-783.