The effect of cyclosporin A on cultured rabbit subconjunctival fibroblast proliferation

Ophthalmologica

Volumn 213, Issue 2, 1999, Pages 114-119

  Baǧci, Gülseren ^a   Yücel, Iclal ^a   Duranoǧlu, Yaşar ^a  

^a AKDENIZ UNIVERSITY   (Turkey)

Author keywords

Cyclosporin A; Fibroblast proliferation; Subconjunctival tissue

Indexed keywords

CYCLOSPORIN A;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONJUNCTIVA; DOSE RESPONSE; FIBROBLAST; GROWTH CURVE; GROWTH INHIBITION; IMMUNOREGULATION; NONHUMAN; RABBIT;

ANIMALS; CELL DIVISION; CELLS, CULTURED; CONJUNCTIVA; CYCLOSPORINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; IMMUNOSUPPRESSIVE AGENTS; RABBITS;

EID: 0033004483     PISSN: 00303755     EISSN: None     Source Type: Journal    
DOI: 10.1159/000027403     Document Type: Article

References (31)

1. Nussenblatt RB, Palestine AG: Cyclosporin: Immunology, pharmacology and therapeutic uses. Surv Ophthalmol 1986;31:159.
2. Kalsi GS, Gudauskas G, Bussanich N, Freeman DJ, Rootman J: Ocular pharmacokinetics of subconjunctivally administered cyclosporine in the rabbit. Can J Ophthalmol 1991;26: 200-205.
3. Harper CA, Khoobehi B, Peyman GA, Geberhardt BM, Dunlap WA: Bioavailability of microsphere entrapped cyclosporine A in the cornea and aqueous of rabbits. Int Ophthalmol 1993-94;17:337-340.
4. Kanpolat A, Batioǧlu F, Yilmaz M, Akbaş F: Penetration of cyclosporin A into the rabbit cornea and aqueous humor after topical drop and collagen shield administration. CLAO J 1994;20:119-122.
5. Player LL, Elkin SB, Ruckert D, Lut ZS, Grammer J, Chou J, Schmidt KH, Mondino BJ: Ocular absorption, collagen based drug delivery and artifical tears. J Ocul Pharmacol 1994;10: 17-27.
6. Holland EJ, Olsen TW, Ketcham JM, Flame C, Krachmer JH, Purcell JJ, Lam S, Tessler HH, Sugar J: Topical cyclosporin A in the treatment of anterior segment inflammatory disease. Cornea 1993;12:413-419.
7. Broadway D, Grierson I, O'Brien C, Hitchings RA: The effect of topical antiglaucoma medication on the conjunctival cell prolife and results of trabeculectomy. Invest Ophthalmol Vis Sci 1993;34:724.
8. Cunliffe IA, Richardson PS, Rees RC, Rennie IG: Effect of TNF, IL-1, and IL-6 on the proliferation of human Tenon's capsule fibroblasts in tissue culture. Br J Ophthalmol 1995;79: 590-595.
9. Kaan G, Özden Ö: Therapeutic use of topical cyclosporine. Ann Ophthalmol 1993;25:182-186.
10. Hemady R, Tauber J, Foster CS: Immunosuppressive drugs in immuno and inflammatory ocular disease. Surv Ophthalmol 1991;35:369-385.
11. James A, Ateer M, Davis J: Basic cell culture technique and the maintenance of cell lines; in Davis JM (ed): Basic Cell Culture. Oxford/New York/Tokyo, IRL Press at Oxford University, 1996, p 123.
12. Belin MW, Bouchard CS, Phillips TM: Update on topical cyclosporin A. Background, immunology and pharmacology. Cornea 1990;9: 184-195.
13. Kaufman Y, Chang AE, Robb RJ, Rosenberg SA: Mechanism of action of cyclosporin A: Inhibition of lymphokine secretion studies with antigen stimulated T cell hybridomas. J Immunol 1984;133:3107-3111.
14. Foets B, Missoten L, Vanderveeren GW: Prolonged survival of allogenic corneal grafts in rabbits treated with topically appliced cyclosporin A: Systemic absorption and local immunosuppressive effect. Br J Ophthalmol 1985; 69:600.
15. Granelli Piperno A, Andrus L, Steinmann RM: Lymphokine and nonlymphokine mRNA levels in stimulated human T cells: Kinetics, mitogen requirements and efects of cyclosporine A. J Exp Med 1986;163:922.
16. Klaus GCB, Hawrolowicz CM: Activation and proliferation signals in mouse B cells. II. Evidence for activation (60-0.61) signals differing in sensitivity to cyclosporine. Eur J Immunol 1984;14:250.
17. Cirillo R, Triggiani M, Siri L, Ciccarelli A, Pettit GR, Condorelli M, Marone G: Cyclosporin A rapidly inhibits mediator release from human basophils presumably by interacting with cyclophilin. Immunology 1990;144:3891-3897.
18. Graham EM, Saunders MD, James DG, Hamblin A, Grochowska EK, Dumonde D: Cyclosporin A in the treatment of posterior uveitis. Trans Ophthalmol Soc UK 1985;104:146-151.
19. Power WJ, Mulleney P, Fornell M, Collin M: Effect of topical cyclosporin A on conjunctival T cells in patients with secondary Sjögren syndrome. Cornea 1993;12:507-511.
20. Kaufman HE, Steinemann TI, Lehman E, Thomson HW, Varnell ED, Jacob La Barre JT, Gebhardt BM: Collagen based drug delivery and artificial tears. J Ocul Pharmacol 1994;10: 17-27.
21. Hill JC: The use of cyclosporine in high risk keratoplasty. Am J Ophthalmol 1989;107:506.
22. Müftüoǧlu AU, Pazarli H, Yurdakul S, Yaziki H, Ulku BY, Tuzun Y, Serdaroglu S, Altug E, Bahcecioglu H, Gungen G: Short term cyclosporin A treatment of Behçet's disease. Br J Ophthalmol 1987;71:387-390.
23. Ben Ezro D, Maftzir G: Ocular penetration of cyclosporine A in the rat eye. Arch Ophthalmol 1990;108:584-587.
24. Hill JC: The use of cyclosporine in high-risk keratoplasty. Am J Ophthalmol 1989;107:506.
25. Holland EJ, Chan C, Kuwabara T, Palestine AG, Rowsey JJ, Nussenblatt RB: Immunohistologic findings and results of treatment with cyclosporine in ligneous conjunctivitis. Am J Ophthalmol 1989;107:160.
26. Ben Ezro D, Peer J, Brodsky M, Cohen E: Cyclosporin eye drops for the treatment of severe vernal keratoconjunctivitis. Am J Ophthalmol 1986;101:278.
27. Zhao JC, Jin XY: Immunological analysis and treatment of Mooren's ulcer with cyclosporine A applied topically. Cornea 1993;12:481-488.
28. Power WJ, Mullaney P, Fairell M, Collum LM: Effect of topical cyclosporine A on conjunctival T cells in patients with secondary Sjögren's syndrome. Cornea 1993;12:597-511.
29. Laibovitz RA, Solch S, Andriano K, O'Ionell M, Silverman MH: Pilot trial of cyclosporine 1% ophthalmic ointment in the treatment of keratoconjunctivitis sicca. Cornea 1993;12: 315-323.
30. Filipec M, Phan TM, Shao TZ, Rice BA, Merchant A, Forester CS: Topical cyclosporine A and corneal wound healing. Cornea 1992;11: 546-552.
31. Zhao JC, Jin XU: Local therapy of corneal allograft rejection with cyclosporine. Am J Ophthalmol 1995;119:189-194.