Ofloxacin otic solution in patients with otitis media: An analysis of drug concentrations

Archives of Otolaryngology - Head and Neck Surgery

Volumn 125, Issue 3, 1999, Pages 337-340

  Ohyama, Masaru ^a,d   Furuta, Shigeru ^a   Ueno, Kazuyoshi ^a   Katsuda, Kenji ^b   Nobori, Takuo ^c   Kiyota, Ryuji ^c   Miyazaki, Yasuhiro ^c  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b Minami Kyushu Hospital   (Japan)

^c Imakiire General Hospital   (Japan)

^d Ohshima Dist Med Assoc Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

OFLOXACIN;

ADOLESCENT; ADULT; AGED; ARTICLE; BACTERIUM ISOLATION; CHILD; CHRONIC OTITIS MEDIA; CLINICAL ARTICLE; DRUG CONCENTRATION; DRUG ELIMINATION; EARDRUM PERFORATION; HUMAN; MIDDLE EAR MUCOSA; OTITIS MEDIA; OTORRHEA; PRESCHOOL CHILD; SCHOOL CHILD; TOPICAL DRUG ADMINISTRATION;

EID: 0033004005     PISSN: 08864470     EISSN: None     Source Type: Journal    
DOI: 10.1001/archotol.125.3.337     Document Type: Article

References (8)

1. Kawamura S, Fujimaki Y, Iwasawa T, et al. A comparative double-blind study of DL-8280 and pipemidic acid in suppurative otitis media [in Japanese]. Otologia Fukuoka. 1984:30:642-670.
2. Heptt W, Lutz H. Clinical experiences with ofloxacin sequential therapy in chronic ear infections. Eur Arch Otorhinolaryngol. 1993;250(suppl):S19-S21.
3. Marshall S, Jones R. In vitro activity of DU-6859a, a new fluorocyclopropyl quinolone. Antimicrobial Agents Chemother. 1993;37:2747-2753.
4. Sato K, Miyazaki T, Araki N, Yamashita K. Experimental study of the influence of ofloxacin (OFLX) otic solution upon the inner ear [in Japanese]. Otologia Fukuoka. 1989;35:58-64.
5. Nobori T, Hanamure Y, Matuzaki T, et al. A study of the influence of ofloxacin on the cochlea after topical administration into the middle ear cavity [in Japanese]. Otologia Fukuoka. 1988;34:1028-1034.
6. Baba S, Kobayashi T, Saito S, et al. Double-blind clinical test result of ofloxacin otic solution for the treatment of suppurative otitis media and its acute exacerbation [in Japanese]. Otologia Fukuoka. 1990;36(suppl 3):564-589.
7. Suzuki K, Ito Y, Kunii H, Ito S, Tsuge I, Baba S. A clinical study of ofloxacin otic solution on suppurative otitis media and otitis externa in children [in Japanese]. Otologia Fukuoka. 1991:37:238-244.
8. Japan Society of Chemotherapy. A method for determining the minimum inhibitory concentration of antimicrobial agents [in Japanese]. Chemotherapy. 1981; 29:76-79.