Meprin B: Transcriptional and posttranscriptional regulation of the meprin β metalloproteinase subunit in human and mouse cancer cells

APMIS

Volumn 107, Issue 1, 1999, Pages 19-27

  Matters, Gail L ^a   Bond, Judith S ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

Meprin expression; mRNA isoforms; Protease; Transcriptional regulation

Indexed keywords

MATRIX METALLOPROTEINASE; MEPRIN;

ANIMAL CELL; ARTICLE; ENZYME INDUCTION; ENZYME SUBUNIT; INTESTINE EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROCESSING; TERATOCARCINOMA; TRANSCRIPTION REGULATION;

EID: 0033003982     PISSN: 09034641     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1699-0463.1999.tb01522.x     Document Type: Article

References (13)

1. 1. Bond JS, Beynon RJ. The astacin family of metalloendopeptidases. Protein Science 1995;4:1247-61.
2. 2. Wolz RL, Bond JS. Meprins A and B. Methods Enzymol 1995;248:325-45.
3. 3. Gorbea CM, Marchand P, Jiang W, Copeland NG, Gilbert DJ, Jenkins NA, Bond JS. Cloning, expression and chromosomal localization of the mouse meprin β subunit. J Biol Chem 1993;268:21035-43.
4. 4. Johnson GD, Hersh LB. Cloning a rat meprin cDNA reveals the enzyme is a heterodimer. J Biol Chem 1992;267:13505-12.
5. 5. Bond JS, Rojas K, Overhauser J, Zoghbi HY, Jiang W. The structural genes MEP1A and MEP1B, for the α and β subunits of the metalloendopeptidase meprin, map to human chromosome 6p and 18q, respectively. Genomics 1995;25:300-3.
6. 6. Dietrich JM, Jiang W, Bond JS. A novel meprin β mRNA in mouse embryonal and human colon cancer cells. J Biol Chem 1996;271:2271-8.
7. 7. Suh E, Chen L, Taylor J, Traber PG. A homeodomain protein related to caudal regulates intestine-specific gene transcription. Mol Cell Biol 1994;14:7340-51.
8. 8. Troelson JT, Mitchelmore C, Spodberg N, Jensen AM, Norén O, Sjöström H. Regulation of lactase-phlorizin hydrolase gene expression by the caudal-related homeodomain protein Cdx-2. Biochem J 1997;322:833-8.
9. 9. Gutman A, Wasylyk B. The collagenase promoter contains a TPA and oncogene-responsive unit encompasing the PEA3 and AP-1 binding sites. EMBO J 1990; 9:2241-6.
10. 10. Gaire M, Magbanua Z, McDonnell S, McNeil L, Lovett DH, Matrisian LM. Structure and expression of the human gene for the matrix metalloproteinase matrilysin. J Biol Chem 1994;269:2032-40.
11. 11. Cavailles V, Augereau P, Rochefort H. Cathepsin D gene is controlled by a mixed promoter, and estrogens stimulate only TATA-dependent transcription in breast cancer cells. Proc Natl Acad Sci USA. 1993; 90:203-7.
12. 12. Chestukhin A, Muradov K, Litovchick L, Shaltiel S. The cleavage of protein kinase A by the kinase-splitting membranal proteinase is reproduced by meprin β. J Biol Chem 1996;271:30272-80.
13. 13. Chestukhin A, Litovchick L, Muradov K, Batkin M, Shatiel S. Unveiling the substrate specificity of meprin β on the basis of the site in protein kinase A cleaved by the kinase splitting membranal proteinase. J Biol Chem 1997;272:3153-60.