Peritoneal irrigation with povidone-iodine solution after laparoscopic- assisted splenectomy significantly decreases port-tumor recurrence in a murine model

Diseases of the Colon and Rectum

Volumn 42, Issue 3, 1999, Pages 319-326

  Lee, Sang W ^a   Gleason, Neil R ^a   Bessler, Marc ^a   Whelan, Richard L ^a,b  

^a New York Presbyterian Hospital Columbia University Medical Center   (United States)

^b NONE   (United States)

Author keywords

Laparoscopy; Peritoneal irrigation; Port wound tumors; Port site tumor recurrence; Povidone iodine; Splenic tumor model

Indexed keywords

POVIDONE IODINE;

ABDOMINAL WALL; ANIMAL CELL; ANIMAL MODEL; ARTICLE; CANCER CELL; COLON ADENOCARCINOMA; CONTROLLED STUDY; FEMALE; LAPAROSCOPIC SURGERY; NONHUMAN; PERITONEUM LAVAGE; SPLEEN TUMOR; SPLENECTOMY; TUMOR LOCALIZATION;

EID: 0033003450     PISSN: 00123706     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02236346     Document Type: Article

References (25)

1. Lee SW, Southall JC, Allendorf JD, Bessler M, Whelan RL. Traumatic handling of the tumor independent of pneumoperitoneum increases port site implantation rate of colon cancer in a murine model. Surg Endosc 1998;12:828-34.
2. Lee SW, Whelan RL, Southall JC, Bessler M. Abdominal wound tumor recurrence after open and laparoscopic-assisted splenectomy in murine model. Dis Colon Rectum 1998;41:824-31.
3. Umpleby HC, Fermor B, Symes MO, et al. Isolation of viable exfoliated colorectal cancer cells at the site of intestinal transection. Br J Surg 1983;70:680.
4. Skipper D, Cooper AJ, Marston JE, et al. Exfoliated cells and in vitro growth in colorectal cancer. Br J Surg 1987;74:1049-52.
5. Smith RR, Thomas LB, Hilber AN. Cell contamination of operative wounds. Cancer 1958;11:53-62.
6. Litsuka Y, Kaneshima S, Tanida O, et al. Intra-peritoneal free cancer cells and their viability in gastric cancer. Cancer 1979;44:1476-80.
7. Jones DB, Guo L-W, Reinhard MK, et al. Impact of pneumoperitoneum on trocar site implantation of colon cancer in hamster model. Dis Colon Rectum 1995;38: 1182-8.
8. Bouvy, ND, Marquet, RL, Jeekel, H, et al. Impact of gas(less) laparoscopy and laparotomy on peritoneal tumor growth and abdominal wall metastases. Ann Surg 1996;224:694-701.
9. Mathew G, Watson DI, Rofe AM, et al. Wound metastases following laparoscopic and open surgery for abdominal cancer in a rat model. Br J Surg 1996;83: 1087-90.
10. Wu JS, Brasfield EB, Guo, LW, et al. Implantation of colon cancer at trocar sites is increased by low pressure pneumoperitoneum. Surgery 1997;122:1-7.
11. Jacobi CA, Sabat R, Bartholomaus B, et al. Pneumoperitoneum with carbon dioxide stimulates growth of malignant colonic cells. Surgery 1997;121:72-8.
12. Lee SW, Bessler M, Whelan RL. Port site tumor recurrence rates in a murine laparoscopic splenectomy model decreased with increased experience [abstract]. Surg Endosc 1998;12:514.
13. Martin JK Jr, Goellner JR. Abdominal fluid cytology in patients with gastrointestinal malignant lesions. Mayo Clin Proc 1986;61:467-71.
14. Murphy PD, Wadhera V, Griffin SM, et al. Free peritoneal tumor cell identification in patients with gastric and colorectal cancer. J R Coll Surg Edinb 1993;38:28-32.
15. Leather AJ, Kocjan G, Savage F, et al. Detection of free malignant cells in the peritoneal cavity before and after resection of colorectal cancer. Dis Colon Rectum 1994; 37:814-9.
16. Hansen E, Wolff N, Knuechel R, et al. Tumor cells in blood shed from the surgical field. Arch Surg 1995;130: 387-93.
17. Zamora JL. Chemical and microbiologic characteristics and toxicity of povidone-iodine solutions. Am J Surg 1986;151:400-6.
18. Lucarotti ME, White H, Deas J, et al. Antiseptic toxicity to breast carcinoma in tissue culture: an adjuvant to conservation therapy? Ann R Coll Surg Engl 1990;72: 388-92.
19. Umpleby HC, Williamson RC. The efficacy of agents employed to prevent anastomotic recurrence in colorectal carcinoma. Ann R Coll Surg Engl 1994;662:192-4.
20. Docherty JG, McGregor, Purdie CA, et al. Efficacy of tumoricidal agents in vitro and in vivo. Br J Surg 1995; 82:1050-2.
21. Lavigne JE, Brown CS, Machiedo GW, et al. The treatment of experimental peritonitis with intraoperative betadine solution. J Surg Res 1974;16:307-11.
22. Pietsch J, Meakins JL. Complications of povidone-iodine absorption in topically treated burn patients. Lancet 1976;1:280-2.
23. Glick PL, Guglielmo J, Tranbaugh RF, et al. Iodine toxicity in a patient treated by continuous povidone-iodine mediastinal irrigation. Ann Thorac Surg 1985;39: 478-80.
24. Keating JP, Neill M, Hill GL. Sclerosing encapsulating peritonitis after intraperitoneal use of povidone-iodine. Aust N Z J Surg 1997;67:742-4.
25. Sindelar WF, Mason GR. Intraperitoneal irrigation with povidone-iodine solution for the prevention of intra-abdominal abscesses in the bacterially contaminated abdomen. Surg Gynecol Obstet 1979;148:409-11.