Optimization of feed rate profile for the monoclonal antibody production

Bioprocess Engineering

Volumn 20, Issue 2, 1999, Pages 137-146

  Lee, J H ^a   Lim, H C ^b   Yoo, Y J ^c   Park, Y H ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b University of California at Irvine   (United States)

^c Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ALGORITHM; ANTIBODY PRODUCTION; ARTICLE; BIOENGINEERING; BIOREACTOR; KINETICS; PRIORITY JOURNAL; PROCESS CONTROL;

EID: 0033003267     PISSN: 0178515X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004490050572     Document Type: Article

References (12)

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3. Batt, B.C.; Kompala, D.S.: A Structured Kinetic Modeling Framework for the Dynamics of Hybridoma Growth and Monoclonal Antibody Production in Continuous Suspension Cultures, Biotechnol. Bioeng. 34 (1989) 515-531
4. Bibila, T.A.; Robinson, D.K.: In pursuit of the Optimal Fed Batch Process for Monoclonal Antibody Production, Biotechnol. Prog. 11 (1995) 1-13
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9. Noe, W.; Schorn, P.; Berthold, W.: Fed batch Strategies for Mammalian Cell Cultures, In Animal Cell Technology: Products of Today, Prospects of Tommorrow. ed by Spier, R.E.; Griffiths, J.B.; and Berthold, W.; Butterworth-Heinemann, Oxford, UK, (1994) 413-418
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12. Lee, J.H.; Hong, J.; Lim, H.C.: Experimental Optimization of a High Cell Density Fedbatch Culture of Alcaligenes eutrophus for the Production of Poly-b-hydroxybutyric Acid. Biotechnol. Bioeng. 56 (1997) 697-705