Enantiomeric analysis of D- and L-pipecolic acid in plasma using a chiral capillary gas chromatography column and mass fragmentography

Journal of Inherited Metabolic Disease

Volumn 22, Issue 5, 1999, Pages 677-678

  Struys, E A ^a   Jakobs, C ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PHYTANIC ACID; PIPECOLIC ACID;

ARTICLE; CAPILLARY GAS CHROMATOGRAPHY; CHIRALITY; DISORDERS OF PEROXISOMAL FUNCTIONS; ELECTRON CAPTURE DETECTION; ENANTIOMER; HUMAN; MASS FRAGMENTOGRAPHY;

GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; ISOMERISM; PIPECOLIC ACIDS;

EID: 0033002865     PISSN: 01418955     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1005558903769     Document Type: Article

References (4)

1. Armstrong DW, Zukowski J, Ercal N, Gasper M (1993) Stereochemistry of pipecolic acid in the urine and plasma of subjects with peroxisomal deficiencies. J Pharm Biomed Anal 11: 881-886.
2. Baumgartner MR, Verhoeven NM, Jakobs C, Roels F, Wanders RJA, Saudubray JM (1998) A very unusual presentation of Refsum disease revealing a new peroxisomal disorder. J Inher Metab Dis 21: 109.
3. Kok RM, Kaster L, DeJong PJM, Poll-The BT, Saudubray JM, Jakobs C (1987) Stable isotope dilution analysis of pipecolic acid in cerebrospinal fluid, plasma, urine and amniotic fluid using electron capture negative ion mass fragmentography. Clin Chim Acta 168: 143-152.
4. 11]pipecolic acid as internal standard. J Chromatogr 574: 335-339.