Effects of pH on kinetic parameters of the Na-HCO3 cotransporter in renal proximal tubule

Biophysical Journal

Volumn 76, Issue 6, 1999, Pages 3066-3075

  Gross, Eitan ^a,b   Hopfer, Ulrich ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BICARBONATE; SODIUM;

ANIMAL CELL; ANION TRANSPORT; ARTICLE; COMPUTER SIMULATION; CONTROLLED STUDY; KIDNEY PROXIMAL TUBULE; NONHUMAN; PH; RAT; SODIUM TRANSPORT; TRANSPORT KINETICS;

ANIMALIA;

EID: 0033001867     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(99)77459-X     Document Type: Article

References (39)

1. Acevedo, M. 1994. Effect of acetyl choline on ion transport in sheep tracheal epithelium. Pflugers Arch. 427:543-546.
2. 3 transport in the rta proximal convoluted tubule. A sodium-coupled electrogenic process. J. Gen. Physiol. 86:613-636.
3. Alpern, R. J., and M. Chambers. 1986. Cell pH in the rat proximal convoluted tubule. Regulation by luminal and peritubular pH and sodium concentration. J. Clin. Invest. 78:502-510.
4. + secretion in the proximal tubule. Am. J. Physiol. 245:F647-F659.
5. + exchanger in renal microvillus membrane vesicles. Nature. 299:161-163.
6. Backman, K., B. Harrison, M. Meysenberg, C. Schwartz, and W. Germann. 1992. Inactivation of a volume-sensitive basolateral potassium conductance in turtle colon: effect of metabolic inhibitors. Biochim. Biophys. Acta. 1105:89-96.
7. Bevington, P. R. 1969. Data Reduction and Error Analysis for the Physical Sciences. McGraw-Hill, New York. 314-315.
8. Biagi, B. A., and M. Sohtell. 1986. Electrophysiology of basolateral transport in the rabbit proximal tubule. Am. J. Physiol. 250:F267-F272.
9. +/amino acid transporter from Arabidopsis thaliana. J. Biol. Chem. 271:2213-2220.
10. 3 transport. J. Gen. Physiol. 81:53-94.
11. Boron, W. F., and E. L. Boulpaep. 1983b. Intracellular pH regulation in the renal proximal tubule of the salamander. Na-H exchange. J. Gen. Physiol. 81:29-52.
12. 3. J. Gen. Physiol. 93:123-150.
13. Chao, J., and D. J. Graves. 1970. pH dependence of the kinetic parameters of maltodextrin phosphorylase. Biochem. Biophys. Res. Commun. 40: 1398-1403.
14. 3 cotransport and K conductance in renal proximal tubules. II. Effect of micromolar concentrations. Pflugers Arch. 427:151-156.
15. Emmett, M., R. J. Alpern, and D. W. Seldin. 1992. Metabolic acidosis. In The Kidney, Physiology and Pathophysiology. D. W. Seldin and G. Giebisch, editors. Raven Press Publishers, New York. 2759-2838.
16. - symporter. Mechanism, stoichiometry, and specificity. J. Biol. Chem. 272:27230-27238.
17. Eyring, H., R. Lumry, and J. W. Woodbury. 1949. Some applications of modern rate theory to physiological systems. Rec. Chem. Prog. 10: 100-114.
18. i-2). J. Gen. Physiol. 112:1-18.
19. Grinstein, S., S. Cohen, and A. Rothstein. 1984. Cytoplasmic pH regulation in thymic lymphocytes by an amiloride-sensitive Na/H antiport. J. Gen. Physiol. 83:341-369.
20. Gross, E., and U. Hopfer. 1995. Regulation of Na rebasorption by Ang II: the role of the membrane potential. J. Am. Soc. Nephrol. 6:338A.
21. 3 cotransport in immortalized renal proximal tubule cells. J. Membr. Biol. 152:245-252.
22. 3 cotransportrer kinetics in renal proximal tubule cells. Biophys. J. 75:810-824.
23. +/myo-inositol cotransporter expressed in Xenopus oocytes. J. Membr. Biol. 143: 103-113.
24. Illek, B., H. Fischer, and W. Clauss. 1993. Quinidine sensitive K+ channels in the basolateral membrane of embryonic coprodeum epithelium: regulation by aldosterone and thyroxine. J. Comp. Physiol. B. 163: 556-562.
25. Jordan, P. 1987. How pore mouth charge distributions alter the permeability of transmembrane ionic channels. Biophys. J. 51:297-311.
26. Kirk, K. L., and D. C. Dawson. 1983. Basolateral potassium channel in turtle colon: evidence for single file flow. J. Gen. Physiol. 82:297-313.
27. Klamo, E. M., M. E. Drew, S. M. Landfear, and M. P. Kavanaugh. 1996. Kinetics and stoichiometry of a proton/myo-inositol cotransporter. J. Biol. Chem. 271:14937-14943.
28. Läuger, P., and P. Jauch. 1986. Microscopic description of voltage effects on ion-driven cotransport systems. J. Membr. Biol. 91:275-284.
29. +-coupled oligopeptide transporter hPEPT1. J. Biol. Chem. 271: 5430-5437.
30. +/glucose cotransporter (SGLT1) currents and fluxes. J. Membr. Biol. 162:101-106.
31. Muller-Berger, S., M. Heyer, M. F. Romero, W. F. Boron, and E. Fromter. 1998. Stoichiometry of rat Na-HCO3 cotransporter (rkNBC) overexpressed in Xenopus laevis oocytes measured using giant patches. J. Am. Soc. Nephrol. 9:9A.
32. Ottolenghi, P. 1971. The effect of hydrogen ion concentration on the simplest steady-state enzyme systems. Biochem. J. 123:445-453.
33. +/glucose cotransporter. J. Biol. Chem. 270:27099-27105.
34. +/glucose cotransporter. II. A transport model under nonrapid equilibrium conditions. J. Membr. Biol. 125: 63-79.
35. 3 cotransporter in basolateral membranes of kidney proximal tubule. J. Clin. Invest. 88: 1135-1140.
36. Woodbury, J. W. 1971. Eyring rate theory model of the current-voltage relationship of ion channels in excitable membranes. In Chemical Dynamics. J. O. Hirschfelder, editor. Wiley, New York. 601-617.
37. Woost, P. G., D. E. Orosz, W. Jin, P. S. Frisa, J. W. Jacobberger, J. G. Douglas, and U. Hopfer. 1996. Immortalization and characterization of proximal tubule cells derived from kidneys of spontaneously hypertensive and normotensive rats. Kidney Int. 50:125-134.
38. Yoshitomi, K., and E. Frömter. 1985. How big is the electrochemical potential difference of Na across rat renal proximal tubular cell membranes in vivo? Pflugers Arch. 405:S121-S126.
39. + exchanger NHE3 and the cytoskeletal protein ezrin. J. Biol. Chem. 273:25856-25863.