Effect of HSR-903, a new fluoroquinolone, on the concentration of theophylline in serum

Antimicrobial Agents and Chemotherapy

Volumn 43, Issue 6, 1999, Pages 1494-1496

  Niki, Yoshihito ^a   Watanabe, Shinsuke ^a   Tamada, Sadao ^a   Yoshida, Koichiro ^a   Miyashita, Naoyuki ^a   Nakajima, Masamitu ^a   Matsushima, Toshiharu ^a   Sekino, Hisayuki ^b   Matsuoka, Osamu ^b  

^a KAWASAKI MEDICAL SCHOOL   (Japan)

^b Sekino Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYLURIC ACID; 3 METHYLXANTHINE; 5 AMINO 7 (7 AMINO 5 AZASPIRO[2.4]HEPT 5 YL) 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 8 METHYL 4 OXO 3 QUINOLINECARBOXYLIC ACID; CIPROFLOXACIN; ENOXACIN; FLEROXACIN; GREPAFLOXACIN; LEVOFLOXACIN; LOMEFLOXACIN; NORFLOXACIN; OFLOXACIN; PAZUFLOXACIN; PEFLOXACIN; PIPEMIDIC ACID; PRULIFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SPARFLOXACIN; TEMAFLOXACIN; THEOPHYLLINE; TOSUFLOXACIN;

AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG METABOLISM; DRUG URINE LEVEL; ENZYME INHIBITION; GASTROINTESTINAL SYMPTOM; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PRURITUS; RASH; THEOPHYLLINE BLOOD LEVEL;

EID: 0033001533     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.43.6.1494     Document Type: Article

References (8)

1. Hashiguchi, K., N. Miyashita, Y. Kubota, S. Tamada, M. Nakabayashi, M. Nakajima, N. Okimoto, Y. Niki, and R. Soejima. 1995. Effect of pazufloxacin on serum concentration of theophylline. Chemotherapy (Tokyo) 43(S-2):270-275.
2. Maesen, F. P. V., J. P. Teengs, C. Baur, and B. I. Davies. 1984. Quinolones and raised plasma concentrations of theophylline. Lancet ii:530.
3. Nakabayashi, M., K. Hashiguchi, N. Miyashita, Y. Kubota, S. Tamada, Y. Niki, and R. Soejima. 1996. Effect of NM441 on serum concentration of theophylline. Chemotherapy (Tokyo) 44(S-1):184-189.
4. Niki, Y., K. Hashiguchi, M. Kimura, N. Okimoto, and R. Soejima. 1992. Quinolone antimicrobial agents and theophylline. Chemotherapy (Tokyo) 40:598-601.
5. Niki, Y., N. Miyashita, Y. Kubota, M. Nakajima, and T. Matsushima. 1997. In vitro and in vivo antichlamydial activities of HSR-903, a new fluoroquinolone antibiotic. Antimicrob. Agents Chemother. 41:857-859.
6. Scott, N. R., J. Chakraborty, and V. Marks. 1986. Determination of the urinary metabolites of caffeine and theophylline by high-performance liquid chromatography. J. Chromatogr. 375:321-329.
7. Takahashi, Y., N. Masuda, M. Otsuki, M. Miki, and T. Nishino. 1997. In vitro activity of HSR-903, a new quinolone. Antimicrob. Agents Chemother. 41: 1326-1330.
8. Wijnands, W. J. A., C. L. A. Van Herwaarden, and T. B. Vree. 1984. Enoxacin raises plasma theophylline concentrations. Lancet ii:108-109.