In vitro assessment of Lipiodol-targeted radiotherapy for liver and colorectal cancer cell lines

British Journal of Cancer

Volumn 79, Issue 11-12, 1999, Pages 1665-1671

  Al Mufti, R A M ^a   Pedley, R B ^a   Marshall, D ^a   Begent, R H J ^a   Hilson, A ^a   Winslet, M C ^a   Hobbs, K E F ^a  

^a ROYAL FREE HOSPITAL   (United Kingdom)

Author keywords

Colorectal liver metastases; In vitro cytotoxicity; Lipiodol therapy; Primary liver cancer; Targeted radiotherapy

Indexed keywords

IODINATED POPPYSEED OIL; IODINE 131; RHODAMINE;

ARTICLE; CANCER RADIOTHERAPY; CELL COUNT; CELL CULTURE; CELL DENSITY; CELL GROWTH; CELL VIABILITY; COLORECTAL CANCER; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG TARGETING; DRUG UPTAKE; ELECTRON MICROSCOPY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; LIVER CANCER; LIVER CELL CARCINOMA; METASTASIS; PRIORITY JOURNAL;

EID: 0033000879     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6690266     Document Type: Article

References (25)

1. ABPI Data Sheet Compendium (1991-1992) The Pharmaceutical Industry, compiled by G Walker. pp. 1199. Datapharm; London
2. Al-Mufti R, Bhattacharya S, Novell JR, Winslet MC and Hobbs KEF (1995a) Intrarterial radiotherapy with Lipiodol-Iodine 131 for irresectable hepatocellular carcinoma. Br J Cancer 72: 19
3. Al-Mufti R, Bhattacharya S, Lewin J, Winslet MC and Hobbs KEF (1995b) In vitro assessment of iodised oil (Lipiodol) uptake in primary and metastatic liver tumours. Br J Cancer 72: 38
4. Al-Mufti RAM, Bhattacharya S, Winslet MC and Hobbs KEF (1996a) Quantification of uptake and retention of iodised oil (Lipiodol) in primary and secondary hepatic malignancy (Abstract presentation). HPB Surgery 9: 72 [P006]
5. Al-Mufti RAM, Bhattacharya S, Hobbs KEF and Winslet MC (1996b) In-vitro assessment of the uptake of Lipiodol by liver tumours: is it a mechanism specific to Lipiodol? (Abstract). HPB Surgery 9: 72 [P005]
6. Bhattacharya S, Dhillon AP, Winslet MC, Davidson BR, Shukla N, Datta Gupta S, Al-Mufti RAM and Hobbs KEF (1996) Human liver cancer cells and endothelial cells incorporate iodised oil. Br J Cancer 73: 877-881
7. BP (1993) The British Pharmacopoeia 1993, Volume II. pp. 967. Published on the Recommendation of the Medicines Commission Pursuant to the Medicines Act 1968. HMSO: London
8. Bretagne J-F, Raoul J-L, Bourget P, Duvauferrier R, Deugneir Y, Faroux R, Ramée A, Herry J-Y and Gastard J (1988) Hepatic artery injection of I-131 labelled lipiodol part II: preliminary results of therapeutic use in patients with hepatocellular carcinoma and liver metastases. Radiology 168: 547-550
9. Chatin I and Bonnrmain B (1992) Composition de Lipiodol Ultra Fluide. Laboratoire Guerbet: France
10. 131I-Lipiodol cytotoxicity in hepatoma cells. Proceedings of the National Science Council, ROC, Part B: Life Sciences 18: 154-160
11. Drewinko B, Romsdahl MM, Yang LY, Ahearn MJ and Trujillo JM (1976) Establishment of a Human Carcinoembryonic Antigen-Producing Colon Adenocarcinoma Cell Line. 36: 467-475
12. Friedman MA (1983) Primary hepatocellular cancer: present results and future prospects. Int J Radiat Oncol Biol Phys 9: 1841-1850
13. Jaffe EA (1987) Cell biology of endothelial cells. Hum Pathol 18: 234-239
14. Jaffe EA, Nachman RL and Becker CG (1973) Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J Clin Invest 52: 2745-2756
15. Knowles BB, Howe CC and Aden DP (1980) Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. Science 209: 497-499
16. Konno T, Maeda H and Iwai K (1983) Effect of arterial administration of high molecular weight anticancer agent SMANCS with lipid lymphographic agent on hepatoma. Eur J Cancer Clin Oncol 19: 1053-1965
17. Konno T, Maeda H, Iwai K, Maki S, Tashiro S, Uchida M and Miyauchi Y (1984) Selective targeting of anti-cancer drug and simultaneous image enhancement in solid tumours by arterially administered lipid contrast medium. Cancer 54: 2367-2374
18. Leibovitz A, Stinson JC, McCombs WB, McCoy CE, Mazur KC and Mabry ND (1976) Classification of human colorectal adenocarcinoma cell line. Cancer Res 36: 4562-4569
19. Madden MV, Krige JEJ, Bailey S, Beningfield SJ, Geddes C, Werner ID and Terblanche J (1993) Randomised trial of targeted chemotherapy with lipiodol and 5-epidoxorubicin compared with symptomatic treatment for hepatoma. Gut 34: 1598-1600
20. Nakakuma K, Tashiro, S and Uemura K (1979) An attempt for increasing effects of hepatic artery ligation for advanced hepatoma (English abstract). Jap-Deutsche Med Beriehte 24: 675-682
21. Nakakuma K, Tashiro S, Hiraoka T, Uemura K, Konno T, Miyauchi Y and Yokoyama I (1983) Studies on anticancer treatment with an oily anticancer drug injected into the ligated feeding hepatic artery for liver cancer. Cancer 52: 2193-2200
22. 131I-Lipiodol. Postgrad Med J 67: 393-395
23. Raoul J-L, Bourguet P, Bretagne JF, Duvanferrier R, Coornaet S, Darnault P, Rammée, Herry JY and Gastard J (1988) Hepatic artery injection of 131-I-labelled lipiodol. Part I: Biodistribution study results in patients with hepatocellular carcinoma and liver metastases. Radiology 168: 541-545
24. Skehan P, Storeng R, Scudiero D, Monks A, McMahon J, Vistica D, Warren JT, Bokesch H, Kenney S and Boyd MR (1990) New colorimetric cytotoxicity assay for anticancer-drug screening. J Natl Cancer Inst 82: 1107-1112
25. Vetter D, Wenger J-J, Bergier J-M, Doffoel M and Bokel R (1991) Transcatheter oily chemoembolization in the management of advanced hepatocellular carcinoma in cirrhosis: results of a Western comparative study in 60 patients. Hepatology 13: 427-433