GAL4 is regulated by the RNA polymerase II holoenzyme-associated cyclin-dependent protein kinase SRB10/CDK8

Molecular Cell

Volumn 3, Issue 5, 1999, Pages 673-678

  Hirst, Martin ^a   Kobor, Michael S ^a   Kuriakose, Neena ^a   Greenblatt, Jack ^a   Sadowski, Ivan ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLINE; GALACTOSE; RNA POLYMERASE II; TRANSCRIPTION FACTOR;

ARTICLE; CONTROLLED STUDY; EPISTASIS; MUTATION; NONHUMAN; PHOSPHORYLATION; TRANSCRIPTION REGULATION; YEAST;

EID: 0033000483     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80360-3     Document Type: Article

References (33)

1. Balciunas, D., and Ronne, H. (1995). Three subunits of the RNA polymerase II mediator complex are involved in glucose repression. Nucleic Acids Res. 23, 4421-4425.
2. Carlson, M. (1997). Genetics of transcriptional regulation in yeast: connections to the RNA polymerase II CTD. Annu. Rev. Cell Dev. Biol. 13, 1-23.
3. Carlson, M., Osmond, B.C., Neigeborn, L., and Botstein, D. (1984). A suppressor of SNF1 mutations causes constitutive high-level invertase synthesis in yeast. Genetics 107, 19-32.
4. Cismowski, M.J., Laff, G.M., Solomon, M.J., and Reed, S.I. (1995). KIN28 encodes a C-terminal domain kinase that controls mRNA transcription in Saccharomyces cerevisiae but lacks cyclin-dependent kinase-activating kinase (CAK) activity. Mol. Cell. Biol. 15, 2983-2992.
5. Cooper, K.F., Mallory, M.J., Smith, J.B., and Strich, R. (1997). Stress and developmental regulation of the yeast C-type cyclin Ume3p (Srb11p/Ssn8p). EMBO J. 16, 4665-4675.
6. Dubois, M.F., Vincent, M., Vigneron, M., Adamczewski, J., Egly, J.M., and Bensaude, O. (1997). Heat-shock inactivation of the TFIIH-associated kinase and change in the phosphorylation sites on the C-terminal domain of RNA polymerase II. Nucleic Acids Res. 25, 694-700.
7. Feaver, W.J., Svejstrup, J.Q., Henry, N.L., and Kornberg, R.D. (1994). Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK. Cell 79, 1103-1109.
8. Hengartner, C., Myer, V., Liao, S., Wilson, C., Koh, S., and Young, R. (1998). Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases. Mol. Cell 2, 43-53.
9. Holstege F., Jennings E., Wyrick J., Lee T., Hengartner, C., Green, M., Golub, T., Lander, E., and Young, R. (1998). Dissecting the regulatory circuitry of a eukaryotic genome. Cell 95, 717-728.
10. Hung, W., Olson, K.A., Breitkreutz, A., and Sadowski, I. (1997). Characterization of the basal and pheromone-stimulated phosphorylation states of Ste12p. Euro. J. Biochem. 245, 241-251.
11. Jiang, Y.W., Veschambre, P., Erdjument-Bromage, H., Tempst, P., Conaway, J., Conaway, R., and Kornberg, R.D. (1998). Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways. Proc. Natl. Acad. Sci. USA 95, 8538-8543.
12. Kang, T., Martins, T., and Sadowski, I. (1993). Wild type GAL4 binds cooperatively to the GAL1-10 UASG in vitro. J. Biol. Chem. 268, 9629-9635.
13. Kuchin, S., and Carlson, M. (1998). Functional relationships of Srb10-Srb11 kinase, carboxy-terminal domain kinase CTDK-I, and transcriptional compressor Ssn6-Tup1. Mol. Cell. Biol. 18, 1163-1171.
14. Kuchin, S., Yeghiayan, P., and Carlson, M. (1995). Cyclin-dependent protein kinase and cyclin homologs SSN3 and SSN8 contribute to transcriptional control in yeast. Proc. Natl. Acad. Sci. USA 92, 4006-4010.
15. Lee, D., and Lis, J.T. (1998). Transcriptional activation independent of TFIIH kinase and the RNA polymerase II mediator in vivo. Nature 393, 389-392.
16. Liao, S.-M., Zhang, J., Jeffery, D.A., Koleske, A.J., Thompson, C.M., Chao, D.M., Viljoen, M., van Vuuren, H.J.J., and Young, R.A. (1995). A kinase-cyclin pair in the RNA polymerase II holoenzyme. Nature 374, 193-196.
17. Mylin, L.M., Bhat, J.P., and Hopper, J.E. (1989). Regulated phosphorylation and dephosphorylation of GAL4, a transcriptional activator. Genes Dev. 3, 1157-1165.
18. O'Brien, T., Hardin, S., Greenleaf, A., and Lis, J. (1994). Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation. Nature 370, 75-77.
19. Pan, G., Aso, T., and Greenblatt, J. (1997). Interaction of elongation factors TFIIS and elongin A with a human RNA polymerase II holoenzyme capable of promoter-specific initiation and responsive to transcriptional activators. J. Biol. Chem. 272, 24563-24571.
20. Patturajan, M., Schulte, R.J., Sefton, B.M., Berezney, R., Vincent, M., Bensaude, O., Warren, S.L., and Corden, J.L. (1998). Growth-related changes in phosphorylation of yeast RNA polymerase II. J. Biol. Chem. 273, 4689-4694.
21. Ptashne, M., and Gann, A. (1997). Transcriptional activation by recruitment. Nature 386, 569-577.
22. Sadowski, I., Niedbala, D., Wood, K., and Ptashne, M. (1991). GAL4 is phosphorylated as a consequence of transcriptional activation. Proc. Natl. Acad. Sci. USA 88, 10510-10514.
23. Sadowski, I., Costa, C., and Dhanawansa, R. (1996). Phosphorylation of Ga14p at a single C-terminal residue is necessary for galactose-inducible transcription. Mol. Cell. Biol. 16, 4879-4887.
24. Schultz, M., Choe, S., and Reeder, R. (1991). Specific initiation by RNA polymerase I in a whole-cell extract from yeast. Proc. Natl. Acad. Sci. USA 88, 1004-1008.
25. Serizawa, H., Makela, T.P., Conaway, J.W., Conaway, R.C., Weinberg, R.A., and Young, R.A. (1995). Association of Cdk-activating kinase subunits with transcription factor TFIIH. Nature 374, 280-282.
26. Sterner, D.E., Lee, J.M., Hardin, S.E., and Greenleaf, A.L. (1995). The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex. Mol. Cell. Biol. 15, 5716-5724.
27. Stone, G., and Sadowski, I. (1993). GAL4 is regulated by a glucose-responsive functional domain. EMBO J. 12, 1375-1385.
28. Strich, R., Slater, M.R., and Esposito, R.E. (1989). Identification of negative regulatory genes that govern the expression of early meiotic genes in yeast. Proc. Natl. Acad. Sci. USA 86, 10018-10022.
29. Svejstrup, J.Q., Feaver, W.J., and Kornberg, R.D. (1996). Subunits of yeast RNA polymerase II transcription factor TFIIH encoded by the CCL1 gene. J. Biol. Chem. 271, 643-645.
30. Thomas, B.J., and Rothstein, R. (1989). Elevated recombination rates in transcriptionally active DNA. Cell 56, 619-630.
31. Valay, J.G., Simon, M., Dubois, M.F., Bensaude, O., Facca, C., and Faye, G. (1995). The KYN28 gene is required both for RNA polymerase II mediated transcription and phosphorylation of the Rpb1 p CTD. J. Mol. Biol. 249, 535-544.
32. Venetianer, A., Dubois, M.F., Nguyen, V.T., Bellier, S., Seo, S.J., and Bensaude, O. (1995). Phosphorylation state of the RNA polymerase II C-terminal domain (CTD) in heat-shocked cells. Possible involvement of the stress-activated mitogen-activated protein (MAP) kinases. Euro. J. Biochem. 233, 83-92.
33. Wahi, M., and Johnson, A.D. (1995). Identification of genes required for alpha 2 repression in Saccharomyces cerevisiae. Genetics 140, 79-90.