The expression of proteolytic enzymes at the dermal invading front of primary cutaneous melanoma predicts metastasis

Pathology Research and Practice

Volumn 195, Issue 3, 1999, Pages 171-175

  Goldmann, Torsten ^a   Suter, Ludwig ^b   Ribbert, Dietrich ^c   Otto, Friedrich ^b  

^a RESEARCH CENTER BORSTEL   (Germany)

^b Fachklinik Hornheide   (Germany)

^c UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Cathepsin; Collagenase; Melanoma; Metastasis; Prognosis; Statistics

Indexed keywords

CATHEPSIN B; CATHEPSIN D; GELATINASE A; PROTEINASE;

ARTICLE; CANCER INVASION; FEMALE; FOLLOW UP; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MELANOMA; METASTASIS; PROGNOSIS; RETROSPECTIVE STUDY;

EID: 0033000365     PISSN: 03440338     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0344-0338(99)80030-2     Document Type: Article

References (25)

1. Allgayer H. Babic R, Grutzner KU, Tarabichi A, Wilhelm Schildberg F, Heiss MM An immunohistochemical assessment of cathepsin D in gastric carcinoma: its impact on clinical prognosis. Cancer 80: 179-187
2. Breslow A (1970) Thickness, cross-sectional areas and depth of invasion in the prognosis of cutaneous melanoma. Ann Surg 172: 902-908
3. Briozzo P, Morisset M, Capony F, Rougeot C, Rochefort H (1988) In vitro degradation of extracellular matrix with 52,000 cathepsin D secreted by breast cancer cells. Cancer Res 18: 3688-3692
4. Chan SJ, San-Segundo B, McCormik MB, Steiner DF (1986) Nucleotide and predicted amino acid sequences of cloned human and mouse preprocathepsin B cDNAs. Proc Natl Acad Sci 83: 7721-7725
5. Cordell JL, Falini B, Erber WN, Gosh AK, Abdulaziz Z, MacDonald S, Pulford KA, Stein H, Mason DY (1984) Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase. J Histochem Cytochem 32: 219-229
6. Cottam DW, Rees RC (1993) Regulation of matrix metalloproteinases: their role in tumor invasion and metastasis. Int J Oncol 2: 861-872
7. Duffy MJ (1987) Do proteases play a role in cancer invasion and metastasis? Eur J Cancer Clin Oncol 23: 583-589
8. Fiedler U (1988) The Biology of Melanoma Metastasis. J Dermatol Surg Oncol 14: 875-881
9. Goldmann T, Ribbert D, Suter L, Brode M and Otto F (1998) Tumor Characteristics Involved in the Metastatic Behaviour as an Improvement in Primary cutaneous Melanoma Prognostics. J Exp Clin Canc Res 17: 483-489
10. Hermanek P, Scheibe O, Spiessl B, Wagner G (1987) UICC, International Union against Cancer, TNM, Klassifikation maligner Tumoren, pp 95-98. Springer-Verlag, Berlin, Heidelberg, New York
11. Honn KV, Timar J, Bazaz R, Sameni M, Ziegler G, Sloane BF (1994) A lipoxygenase metabolite, 12-(S)-HETE, stimulates protein kinase C-mediated releases of cathepsin B from malignant cells. Exp Cell Res 214: 120-130
12. Kirschke H, Barret AJ (1987) Chemistry of lysosomal proteases. In: Lysosomes. Their Role in Protein breakdown, pp 193-238. Academic Pr, London
13. Liotta LA, Stetler-Stevenson WG (1991) Tumor Invasion and Metastasis: An Imbalance of Positive and Negative Regulation. Cancer Res (Suppl) 51: 5040-5049
14. Liotta LA, Tryggvason K, Garbisa S, Robey PG, Abe S (1981) Partial purification and characterization of a neutral protease which cleaves type IV collagen. Biochemistry 20: 100-108
15. Monteagudo C, Merino MJ, San-Juan J, Liotta LA, Stetler-Stevenson WG (1990) Immunhistochemical Distribution of Type IV Collagenase in Normal, Benign and Malignant Breast Tissue. Am J Pathology 136: 585-592
16. Mort JS, Leduc M, Recklies AD (1981) A latent proteinase from ascites fluid of patients with neoplasia. Biochim Biophys Acta 662: 173-180
17. Qian F, Chan SJ, Achkar C, Steiner DF, Frankfater A (1994) Transcriptional regulation of cathepsin B expression in B16 melanomas of varying metastatic potential. Biochem Biophys Res Commun 202: 429-436
18. Rochefort H, Augerau P, Briozzo P, Capony F, Cavailles V, Freiss G, Garcia M, Maudelonde T, Morisset M, Vignon F (1988) Structure, function, regulation and clinical significance of the 52 kD pro-cathepsin D secreted by breast cancer cells. Biochemie 10: 943-949
19. Sachs L (1984) Angewandte Statistik (6th edition). Springer-Verlag, Berlin, Heidelberg, New York
20. Sivestrini R, Veneroni S, Benini E, Di Fronzo G, Daidone MG (1992) p53 and cathepsin D are independent of established prognostic factors in breast cancer. Int J Oncol 1: 507-512
21. Spiegel MR (1990) Statistik (2nd edition). McGraw-Hill Book Company, Hamburg
22. Stetler-Stevenson WG, Krutzsch HC, Wacher MP, Margulies IMK, Liotta LA (1989) The activation of human type IV collagenase proenzyme. Sequence identification of the major conversion product following organomercurial activation. J Biol Chem 264: 1353-1356
23. Suter L, Bröcker EB, Ostmeier H, Schumann J, Sorg Cl (1989) Metastatic human melanoma. Phenotypic heterogeneity and antigen expression in relation to the clinical status. J Cancer Res Clin Oncol 115: 459-464
24. Wang M, Stearns ME (1988) Blocking of Collagenase IV Secretion by Estramustine during in Vitro Tumor Cell Invasion. Cancer Res 48: 6262-6271
25. Zelger B, Hittmair A, Schir M, Öfner C, Fritsch PO, Böcker W, Jasani B, Schmid KW (1993) Immunohistochemically demonstrated metallothionein expression in malignant melanoma. Histopathology 23: 257-264