New thrombolytic drugs

Australian and New Zealand Journal of Medicine

Volumn 29, Issue 3, 1999, Pages 433-435

  Thomson, A ^a  

^a ROYAL HOBART HOSPITAL   (Australia)

Author keywords

Plasminogen activators; Thrombolytic drugs

Indexed keywords

FIBRIN ANTIBODY; FIBRINOLYTIC AGENT; FIBROLASE; MONOCLONAL ANTIBODY; MUTANT PROTEIN; NEW DRUG; PLASMINOGEN ACTIVATOR; PROUROKINASE; RECOMBINANT PLASMINOGEN ACTIVATOR; SARUPLASE; SNAKE VENOM; STAPHYLOKINASE; TISSUE PLASMINOGEN ACTIVATOR DERIVATIVE; UROKINASE;

BAT; CONFERENCE PAPER; DRUG EFFICACY; DRUG RESEARCH; FIBRINOLYTIC THERAPY; HEART INFARCTION; HUMAN; NONHUMAN; SNAKE;

EID: 0032999130     PISSN: 00048291     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1445-5994.1999.tb00739.x     Document Type: Conference Paper

References (6)

1. 1. De Wood MA, Spores J, Notske R et al. Prevalence of total coronary occlusion during the early hours of transmural myocardial infarction. N Engl J Med 1980; 303: 897-902.
2. 2. Bode C, Smalling RW, Berg G et al. Randomized comparison of coronary thrombolysis achieved with double-bolus reteplase (recombinant plasminogen activator) and front-loaded, accelerated alteplase (recombinant tissue plasminogen activator) in patients with acute myocardial infarction. Circulation 1996; 94: 891-8.
3. 3. Bergum PW, Gardell SJ. Vampire bat salivary plasminogen activator exhibits a strict and fastidious requirement for polymeric fibrin as its cofactor unlike human tissue-type plasminogen activator. J Biol Chem 1992; 267: 17726-31.
4. 4. Vanderschueren S, Barrios L, Kerdsinchai P et al., for the STAR Trial Group. A randomized trial of recombinant staphylokinase versus alteplase for coronary artery patency in acute myocardial infarction. Circulation 1995; 92: 2044-9.
5. 5. PRIMI Trial Study Group. Randomised double-blind trial of recombinant pro-urokinase against steptokinase in acute myocardial infarction. Lancet 1989; 1: 863-8.
6. 6. Markland FS, Friedrichs GS, Pewitt SR et al. Thrombolytic effects of recombinant fibrolase or APSAC in a canine model of carotid artery thrombosis. Circulation 1994; 90: 2448-56.