Effects of nicardipine on collar-induced intimal thickening and vascular reactivity in the rabbit

Journal of Pharmacy and Pharmacology

Volumn 51, Issue 4, 1999, Pages 441-447

  Kerry, Zeliha ^a   Yasa, Mukadder ^a   Akpinar, Riyad ^a   Sevin, Gülnur ^a   Yetik, Günay ^a   Tosun, Metiner ^a   Özdemir, Necmettin ^a   Erhan, Yildiz ^a   Üstünes, Levent ^a   Özer, Asli ^a  

^a EGE UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; CALCIUM CHANNEL BLOCKING AGENT; GLYCERYL TRINITRATE; NICARDIPINE; PHENYLEPHRINE; POTASSIUM CHLORIDE; SEROTONIN; SILASTIC;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY CONSTRICTION; ARTERY INTIMA PROLIFERATION; ARTICLE; BLOOD VESSEL REACTIVITY; CAROTID ARTERY; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; MALE; NONHUMAN; RABBIT; SUBCUTANEOUS DRUG ADMINISTRATION; VASODILATATION;

ACETYLCHOLINE; ANIMALS; BODY WEIGHT; CALCIUM CHANNEL BLOCKERS; CAROTID ARTERIES; CAROTID ARTERY DISEASES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; MALE; NICARDIPINE; NITROGLYCERIN; PHENYLEPHRINE; RABBITS; SEROTONIN; SURVIVAL RATE; TUNICA INTIMA; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS; VASODILATION; VASODILATOR AGENTS;

EID: 0032998704     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357991772493     Document Type: Article

References (23)

1. Arakawa, H., Mutoh, S., Hirosumi, J., Yamaguchi, I. (1992) Effect of nilvadipine on balloon catheterization-induced intimai thickening of the coronary artery in miniature pigs. J. Cardiovasc. Pharmacol. 20: 731-734
2. Beesley, J., Honey, A. C., Martin, J. F. (1992) Ultrastructural assessment of lesion development in the collared rabbit carotid artery model. Cells Materials 2: 201-203
3. Booth, R. F. G., Martin, J. F., Honey, A. C., Hassall, D. G., Beesley, J. E., Moncada, S. (1989) Rapid development of atherosclerotic lesions in the rabbit carotid artery induced by perivascular manipulation. Atherosclerosis 76: 257-268
4. Catapano, A. L. (1992) The anti-atherogenic potential of calcium antagonists: experimental evidence. J. Cardiovasc. Pharmacol. 20: S44-S50
5. De Meyer, G. R. Y., Bult, H., Martin, J. F., van Hoydonck, A.-E., Herman, A. G. (1990) The effect of a developing neointima on serotonergic and adrenergic contractions. Eur. J. Pharmacol. 187: 519-524
6. De Meyer, G. R. Y., Bult, H., van Hoydonck, A.-E., Jordaens, F. H., Buyssens, N., Herman, A. G. (1991) Neointima formation impairs endothelial muscarinic receptors while enhancing prostacyclin-mediated responses in the rabbit carotid artery. Circ. Res. 68: 1669-1680
7. De Meyer, G. R. Y., Bult, H., Üstünes, L., Kockx, M., Jordaens, F. H., Zonnekeyn, L. L., Herman, A. G. (1994) Vasoconstrictor responses after neo-intima formation and endothelial removal in the rabbit carotid artery. Br. J. Pharmacol. 112: 471-476
8. Hadeishi, H., Mayberg, M. R., Seto, M., Dacey, R. G., Solomon, R. A. (1994) Local application of calcium antagonists inhibits intimal hyperplasia after arterial injury. Neurosurgery 34: 114-121
9. Jayakody, R. L., Kappagoda, C. T. T., Senaratne, M. P. J., Sreeharan, N. (1987) Absence of effect of calcium antagonists on endothelium-dependent relaxation in rabbit aorta. Br. J. Pharmacol. 91: 155-164
10. Jayakody, L., Kappagoda, T., Senaratne, M. P. J., Thomson, A. B. R. (1988) Impairment of endothelium-dependent relaxation: an early marker for atherosclerosis in the rabbit. Br. J. Pharmacol. 94: 335-346
11. Kockx, M. M., De Meyer, G. R. Y., Jacob, W. A., Bult, H., Herman, A. G. (1992) Triphasic sequence of neointimal formation in the cuffed carotid artery of the rabbit. Arterioscler. Thromb. 12: 1447-1457
12. Nakao, J., Ito, H., Ooyama, T., Chang, W. C., Murata, S. (1983) Calcium dependency of aortic smooth muscle cell migration induced by 12-L-hydroxy-5,8,10,14-eicosatetraenoic acid. Atherosclerosis 46: 309-319
13. Nilsson, J., Sjolund, M., Palmberg, L., Von Euler, A. M., Jonzon, B., Thyberg, J. (1985) The calcium antagonist nilvadipine inhibits arterial smooth muscle cell proliferation. Atherosclerosis 58: 109-122
14. Nomoto, A., Hirosumi, J., Sekiguchi, C., Mutoh, S., Yamaguchi, I., Aoki, H. (1987) Anti-atherogenic activity of FR34235 (Nilvadipine), a new potent calcium antagonist. Atherosclerosis 64: 255-261
15. Paoletti, R., Bernini, F., Corsini, A., Soma, M. R. (1995) The anti-atherosclerotic effects of calcium antagonists. J. Cardiovasc. Pharmacol. 25: S6-S10
16. Ross, R. (1993) The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362: 801-803
17. Soma, M. R., Donetti, E., Parolini, C., Barben, L., Paoletti, R., Fumagalli, R., Catapano, A. L. (1994) Effect of lacidipine on the carotid intimai hyperplasia induced by cuff injury. J. Cardiovasc. Pharmacol. 23: S71-S74
18. Stary, H. C., Blankenhorn, D. H., Chandler, A. B., Glakow, S., Insull, W., Richardson, J. R., Rosenfeld, M. E., Schaffer, S. A., Schwartz, C. J., Wagner, W. D., Wissler, R. W. (1992) A definition of the intima of human arteries and of its atherosclerosis-prone regions. Arterioscler. Thromb. 12: 120-134
19. Üstünes, L., Yasa, M., Kerry, Z., Özdemir, N., Berkan, T., Erhan, Y., Özer, A. (1996) Effect of verapamil on intimai thickening and vascular reactivity in the collared carotid artery of the rabbit. Br. J. Pharmacol. 118: 1681-1688
20. van Put, D. J. M., van Hove, C. E., De Meyer, G. R. Y., Wuyts, F., Herman, A. G., Bult, H. (1995) Dexamethasone influences intimal thickening and vascular reactivity in the rabbit collared carotid artery. Eur. J. Pharmacol. 294: 753-761
21. Verbeuren, T. J., Jordaens, F. H., Zonnekeyn, L. L., van Hove, C. E., Coene, M.-C., Herman, A. G. (1986) Effect of hypercholesterolemia on vascular reactivity in the rabbit. I. Endothelium-dependent and endothelium-independent contractions and relaxations in isolated arteries of control and hypercholesterolemic rabbits. Circ. Res. 58: 552-564
22. Vrints, C. J. M., Bult, H., Bosmans, J., Herman, A. G., Snoeck, J. P. (1992) Paradoxical vasoconstriction as a result of acetylcholine and serotonin in diseased human coronary arteries. Eur. Heart J. 13: 824-831
23. Weinstein, D. B., Heider, J. G. (1987) Anti-atherogenic properties of calcium antagonists. Am. J. Cardiol. 59: 163B-172B