High prevalence of HCV-RNA in the saliva cell fraction of patients with chronic hepatitis C but no evidence of HCV transmission among sexual partners

Infection

Volumn 27, Issue 2, 1999, Pages 86-91

  Fabris, P ^a,c   Infantolino, D ^a   Biasin, M R ^a   Marchelle, G ^a   Venza, E ^a   Terribile Wiel Marin, V ^b   Benedetti, P ^b,c   Tositti, G ^c   Manfrin, V ^a   De Lalla, F ^d   Giulia Tosilti, M D ^a   Manfrin, M D V ^a   De Lalla, M D F ^a   Bortolo, Ospedale S ^a  

^a Dept of Infectious Diseases ^*

^b Tech   (Italy)

^c Montebelluna and Castelfranco Veneto Hospitals   (Italy)

^d UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS RNA;

ADULT; ARTICLE; CELL FRACTIONATION; CLINICAL ARTICLE; FEMALE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HYBRIDIZATION; MALE; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SALIVA ANALYSIS; SEXUALLY TRANSMITTED DISEASE; VIRUS TITRATION; VIRUS TRANSMISSION;

EID: 0032997278     PISSN: 03008126     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02560503     Document Type: Article

References (41)

1. Alter, M. J., Coleman, P. J., Alexander, W. J., Kramer, E., Miller, J. K., Mandel, E., Hadlcr, S. C., Margolis, H. S.: Importance of heterosexual activity in the transmission of hepatitis B and non-A, non-B hepatitis. JAMA 262 (1989) 1201-1205.
2. Alter, M. J.: Inapparent transmission of hepatitis C: footprints in the sand. Hepatology 14 (1991) 389-391.
3. Alter, M. J., Hadler, S. C., Judson, F. N., Mares, A., Alexander, W. J., Hu, P. Y., Miller, J. K., Moyer, L. A., Fields, H. A., Bradley, D. W.: Risk factors for acute non-A, non-B hepatitis in the United States and association with hepatitis C virus infection. JAMA 264 (1990) 2231-2235.
4. Zanetti, A. K., Tanzi, E., Paccagnini, S., Principi, N., Pizzocolo, G., Caccamo, M. L., D'Amico, E., Gambie, G., Vecchi, L.: Mother-to-child transmission of hepatitis C virus. Lancet 345 (1995) 289-291.
5. Nishioka, K., Watanabe, J., Furuta, S., Tanaka, E., Suzuki, H., Lino, S., Tsuji, T., Yano, M., Kuo, G., Choo, Q. L.: Antibody to the hepatitis C virus in acute hepatitis and chronic liver diseases in Japan. Liver 11 (1991) 65-70.
6. Hollingcr, F. B., Lin, H. J.: Community-acquired hepatitis C virus infection. Gastroenterology 102 (1992) 1426-1429.
7. Abe, K., Kurata, T., Shikata, T., Sugitani, M., Oda, T.: Experimental transmission of non-A, non-B hepatitis by saliva. J. Infect. Dis. 155 (1987) 1078-1079.
8. Dusheiko, G. M., Smith, M., Sheuer, P. J.: Hepatitis C virus transmitted by human bite. Lancet 336 (1990) 503-504.
9. Takamatsu, K., Koyanagi, Y., Okita, K., Yamamoto, N.: Hepatitis C virus RNA in saliva. Lancet 336 (1990) 1515.
10. Hsu, H. H., Wright, T. L., Luba, D., Martin, M., Feinstone, S. M., Garcia, G., Greenberg, H. B.: Failure to detect hepatitis C virus genome in human secretions with the polymerase chain reaction. Hepatology 5 (1991) 763-767.
11. Knödell, R. G., Ishak, H. G., Black, W. C., Chen, T. S., Craig, C., Kaplow itz, N., Kiernan,T. W., Wollman, J.: Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology 1 (1981) 431-435.
12. Imberti, L., Cariani, E., Bettinardi, A., Zonaro, A., Albcrtini, A., Primi, D.: An immunoassay for specific amplified HCV sequences. J. Virol. Methods 34 (1991) 233-243.
13. Viasoz, S., Ziberf, A., Ramakrishnan, K., Widel, A., Caricchini, A., Schreier, E., Roggendorf, M.: Typing of hepatitis C virus isolates by DNA immunoassay. J. Virol. Methods 48 (1994) 81-92.
14. Simmonds, P., Albert!, A., Alter, H. J., Bonino, F., Bradley, D. W., Brechet, C., Brower, J. T., Chan, S. W., Chajama, K., Chen, D. S., Choo, Q. L., Colombo, M., Cuypers, H. T. M., Date, T., Dusheiko, G. M., Esteban, J. I., Fay, O., Hadziyannis, S. Y., Han, J., Hatzakis, A., Holmes, E. C., Hotta, H., Houghton, M., Irvine, B., Kohara, M., Kolberg, J. A., Kuo, G., Lau, J. Y. N., Lelie, P., Martens, G., McOmish, F., Miyamura, T., Mizokami, M., Nomoto, A., Prince, A. M., Recsink, H. W., Rice, C., Roggendorf, M., Schalm, S. W., Shikata, T., Shimotohno, K., Stuyver, I., Trepö, C., Weiner, A., Yap, P. L., Urdea, M. S.: A proposed system for the nomenclature of hepatitis C viral genotypes. Hepatology 19 (1994) 1321-1324.
15. Detmer, J., Lagier, R., Flynn, J., Zayati, C., Kolberg, J., Collins, M., Urdea, M., Sanchez-Pescador, R.: Accurate quantification of hepatitis C virus RNA (HCV-RNA) from all HCV genotypes by using branched DNA technology. J. Clin. Microbiol. 34 (1996) 901-907.
16. Chiaramonte, M., Stroffolini, T., Lorenzoni, U., Minniti, F., Conti, S., Floreani, A., Ntakirutimana, E., Vian, A., Ngatchu, T., Naccarato, R.: Risk factors in community-acquired chronic hepatitis C virus infection: a case control study in Italy. J. Hepatol. 24 (1996) 129-134.
17. Abe, K., Inchauspe, G.: Transmission of hepatitis C by saliva. Lancet 337 (1991) 248.
18. Klein, R. S., Freeman, K.,Taylor, P. E., Stevens, C. E.: Occupational risk of hepatitis C virus infection among New York City dentists. Lancet 338 (1991) 1539-1542.
19. Thomas, D. L., Gruninger, S. E., Siew, C., Joy, E. D., Quinn, T. C.: Occupational risk of hepatitis C infections among general dentists and oral surgeons in North America. Am. J. Med. 100 (1996) 41-45.
20. Wang, J. T., Wang, T. H., Lin, J. T., Sheu, J. C., Lin, S. M., Chen, D. S.: Hepatitis C virus RNA in saliva of patients with post-transfusion hepatitis C infection. Lancet 337 (1991) 48.
21. Komiyama, K., Moro, I., Mastuda, Y., Morshed, S. A., Nishioka, M., Hayashi, N., Shikata, T.: HCV in saliva of chronic patients having dental treatment. Lancet 338 (1991) 572-573.
22. Nakano, I., Imomoto, M., Fukuda, Y., Koyama, Y., Urano, F., Kanda, N., Isobe, K.: Hepatitis C virus RNA in urine, saliva, and sweat. Am J. Gastroenterol. 87 (1992) 1522.
23. Fried, M. W., Shindo, M., Fong, T. L., Fox, P. C., Hoofnaglc, J. H., Di Biseglie, A. M.: Absence of hepatitis C viral RNA from saliva and semen of patients with chronic hepatitis C. Gastroenterology 102 (1992) 1306-1308.
24. Wang, J. T., Wang, T. H., Lin, J. T., Sheu, J. C., Lin, J. T., Chen, D. S.: Hepatitis C virus RNA in saliva of patients with posttransfusion hepatitis and low efficiency of transmission among spouses. J. Med. Virol. 36 (1992) 28-31.
25. Liou, T. C., Chang, T. T., Young, K. C., Lin, X. Z., Lin, C. Y., Wu, H. L.: Detection of HCV-RNA in saliva, urine, seminal fluid and ascites. J. Med. Virol. 37 (1992) 197-202.
26. Couzigou, P., Richard, L., Dumas, F., Schouler, L., Floury, H.: Detection of HCV-RNA in saliva of patients with chronic hepatitis C. Gut (Suppl.) (1993) S59-S60.
27. Numata, N., Ohori, H., Hayakawa, Y., Saitoh, Y., Tsunoda, A., Kanno, A.: Demonstration of hepatitis C virus genome in saliva and urine of patients with type C hepatitis: usefulness of the single-round polymerase chain reaction method for detection of the HCV genome. J. Med. Virol. 41 (1993) 120-128.
28. Ogasawara, S., Kage, M., Kosai, K. I., Shimamatsu, K., Kojiro, M.: Hepatitis C virus RNA in saliva and breast milk of hepatitis C carrier mothers. Lancet 341 (1997) 561.
29. Young, K. C., Chang, T. T., Liou, T. C., Wu, H. L.: Detection of hepatitis C virus RNA in peripheral blood mononuclear cells and in saliva. J. Med. Virol. 41 (1993) 55-60.
30. Slöckl, E. P., Mor, W., Kundi, M., Heinz, F. X., Hofntann, H., Kunz, C.: Prevalence of hepatitis C virus RNA in serum and throat washing of children with chronic hepatitis. J. Med. Virol. 43 (1994) 143-147.
31. Chen, M., Yun, Z. B., Sälbcrg, M., Schvarcz, R., Bcrgquist, I., Berglund, H. B., Sönncrborg, A.: Detection of hepatitis C virus RNA in the cell fraction of saliva before and after oral surgery. J. Med. Virol. 43 (1995) 223-226.
32. Sugimura, H., Yamamoto, H., Walabiki, H., Ogaiva, H., Harada, H., Sailoh, I., Mivamura, T., Inouc, M., Tajima, K., Kino, L: Correlation of detectability of hepatitis C virus genome in saliva of elderly Japanese symptomatic HCV carriers with their hepatic function. Infection 23 (1995) 258-262.
33. Roy, K. M., Bagg, J., Bird, G. L., Spence, E., FolleU, E. A., Mills, P. R., Lau, J. Y.: Serological and salivary markers compared with biochemical markers for monitoring interferon treatment for hepatitis C virus infection. J. Med. Virol. 47 (1995) 429-434.
34. Tang, Z., Yang, D., Hao, L.,Tang, Z., Huang, Y., Wang, S.: Detection and significance of HCV-RNA in saliva, seminal fluid and vaginal discharge in patients with hepatitis C. J.Tongji Med. Univ. 16 (1996) 11-13.
35. Jorgensen, C., Legouffe, M. C., Perney, P., Coste, J., Tissot, B., Segarra, C., Bologna, C., Bourrât, L., Combe, B., Blanc, F., Sany, J.: Sicca syndrome associated with hepatitis C virus infection. Arthritis Rheum. 39 (1996) 1166-1171.
36. Caldwell, S. H., Sue, M., Bowden, J. H., Dickson, R. C., Driscoll, C. J., Yeaton, P., Stevenson, W. C., Ishilani, M. B., McCullough, C. S., Pruett,T. L., Lovel, M. A.: Hepatitis C virus in body fluid after liver transplantation. Liver Transplant Surgery 2 (1996) 124-120.
37. Roy, K. M., Bagg, J., Foliett, E. A., Brewer, A., Lowe, G. D.: Hepatitis C virus in saliva of hemophiliac patients attending an oral surgery unit. Br. J. Oral Maxillofac. Surg. 34 (1996) 162-165.
38. Kage, M., Ogasanara, S., Kosai, K., Nakashima, E., Shimamatsu, K., Kojiro, M., Kimura, A., Fujisawa, T., Matsukuma, Y., Ito, Y., Kondo, S., Kawano, K., Sata, M.: Hepatitis C virus RNA present in saliva but absent in breast milk of the hepatitis C carrier mother. J. Gastroenterol. Hepatol. 12 (1997) 518-521.
39. Üstündag, Y., Hizel, N., Boyacioglu, S., Akalm, E.: Detection of hepatitis GB virus and HCV genomes in the saliva of patients undergoing maintenance haemodialyses. Nephrol. Dial. Transplant. 12 (1987) 2807.
40. Taliani, G., Celestino, D., Badolato, M. C., Pennica, A., Bozza, A., Poliandri, G., Riccieri, V., Benfari, G., Sebastiani, A., De Bac, C., Quaranta, G., Aceti, A.: Hepatitis C virus infection in salivary gland epithelial cells. J. Hepatol. 26 (1997) 1200-1206.
41. Roy, K. M., Bagg, J., McCarron, B., Good,T., Cameron, S., Pithie, A.: Predominance of HCV type 2a in saliva from intravenous drug users. J. Med. Virol. 44 (1998) 271-275.