Differential effects of octreotide treatment and transsphenoidal surgery on growth hormone-binding protein levels in patients with acromegaly

Journal of Neurosurgery

Volumn 90, Issue 4, 1999, Pages 647-650

  Hernandez, Irma ^a   Soderlund, Daniela ^a   Espinosa De Los Monteros, Ana Laura ^a   Ochoa, Raquel ^a   Zarate, Arturo ^a   Mercado, Moisés ^a  

^a HOSPITAL DE ESPECIALIDADES   (Mexico)

Author keywords

Acromegaly; Growth hormone; Growth hormone binding protein; Insulin like growth factor I; Insulin like growth factor binding protein 3; Octreotide

Indexed keywords

GROWTH HORMONE; GROWTH HORMONE BINDING PROTEIN; OCTREOTIDE; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C;

ACROMEGALY; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; GROWTH HORMONE BLOOD LEVEL; HORMONE INHIBITION; HUMAN; HYPOPHYSIS; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SUBCUTANEOUS DRUG ADMINISTRATION; TRANSSPHENOIDAL SURGERY; TREATMENT OUTCOME;

EID: 0032996813     PISSN: 00223085     EISSN: None     Source Type: Journal    
DOI: 10.3171/jns.1999.90.4.0647     Document Type: Article

References (19)

1. Amit T, Ish-Shalom S, Glaser B, et al: Growth hormone-binding protein in patients with acromegaly. Horm Res 37: 205-211, 1992
2. Baumann G, MacCart JG, Amburn K: The molecular nature of circulating growth hormone in normal and acromegalic man: evidence for a principal and minor monomeric forms. J Clin Endocrinol Metab 56:946-952, 1983
3. Baumann G, Mercado M: Growth hormone-binding proteins in plasma. Nutrition 9:546-553, 1994
4. Baumann G, Stolar MW, Amburn K, et al: A specific growth hormone binding protein in human plasma: initial characterization. J Clin Endocrinol Metab 62:134-141, 1986
5. Fisker S, Kaal A, Montini M, et al: Growth hormone binding protein and growth hormone availability in acromegalic patients treated with long-acting octreotide (Sandostatin-LAR). Eur J Endocrinol 136:61-66, 1997
6. Ho KY, Weissberger AJ, Marbach P, et al: Therapeutic efficacy of the somatostatin analog SMS 201-995 (octreotide) in acromegaly. Effect of dose and frequency and long-term safety. Ann Intern Med 112:173-181, 1990
7. Hochberg Z, Barkey RJ, Even L, et al: The effect of human growth hormone therapy on GH binding protein in GH-deficient children. Acta Endocrinol 125:23-27, 1991
8. Johannsson G, Bjarnason R, Bramnert M, et al: The individual responsiveness to growth hormone (GH) treatment in GH-deficient adults is dependent on the level of GH-binding protein, body mass index, age, and gender. J Clin Endocrinol Metab 81:1575-1581, 1996
9. Kratzsch J, Blum WF, Ventz M, et al: Growth hormone-binding protein-related immunoreactivity in the serum of patients with acromegaly is regulated inversely by growth hormone concentration. Eur J Endocrinol 132:306-312, 1995
10. Leung DW, Spencer SA, Cachianes G, et al: Growth hormone receptor and serum binding protein: purification, cloning and expression. Nature 330:537-543, 1987
11. Losa M, Oeckler R, Schopohl J, et al: Evaluation of selective transsphenoidal adenomectomy by endocrinological testing and somatomedin-C measurement in acromegaly. J Neurosurg 70: 561-567, 1989
12. MacFarlane IA, Stafford S, Wright AD: Circulating growth hormone forms in Type I diabetic subjects: comparison with normal subjects and acromegalics. Acta Endocrinol 112: 547-551, 1986
13. Maiter D, Underwood LE, Macs M, et al: Different effects of intermittent and continuous growth hormone (GH) administration on serum somatomedin-C/insulin-like growth factor I and liver GH receptors in hypophysectomized rats. Endocrinology 123:1053-1059, 1988
14. Martha PM Jr, Reiter EO, Dávila N, et al: Serum growth hormone (GH)-binding protein/receptor: an important determinant of GH responsiveness. J Clin Endocrinol Metab 75: 1464-1469, 1992
15. Mercado M, Baumann G: Growth hormone binding proteins. Endocrinologist 3:268-277, 1993
16. Mercado M, Carlsson L, Vitangcol R, et al: Growth hormone-binding protein determination in plasma: a comparison of immunofunctional and growth hormone-binding assays. J Clin Endocrinol Metab 76:1291-1294, 1993
17. Roelen CAM, Donker GH, Thijssen JHH, et al: High affinity growth hormone binding protein in plasma of patients with acromegaly and the effect of octreotide treatment. Clin Endocrinol 37:373-378, 1991
18. Serri O, Somma M, Comtois R, et al: Acromegaly: biochemical assessment of cure after long term follow-up of transsphenoidal selective adenomectomy. J Clin Endocrinol Metab 61: 1185-1189, 1985
19. Vance ML, Harris AG: Long-term treatment of 189 acromegalic patients with the somatostatin analog octreotide. Results of the International Multicenter Acromegaly Study Group. Arch Intern Med 151:1573-1578, 1991