Histochemical and genetic analysis of colonic mucin glycoproteins in Hirschsprung's disease

Journal of Pediatric Surgery

Volumn 34, Issue 2, 1999, Pages 330-333

  Aslam, A ^a,b   Spicer, R D ^a   Corfield, A P ^a  

^a BRISTOL ROYAL HOSPITAL FOR CHILDREN   (United Kingdom)

^b BIRMINGHAM CHILDREN S HOSPITAL   (United Kingdom)

Author keywords

Hirschsprung's disease; Mucin glycoproteins; Mucin secreting gene

Indexed keywords

ALCIAN BLUE; GLYCOPROTEIN; IRON; MONOCLONAL ANTIBODY; MUCIN;

ACETYLATION; AUTORADIOGRAPHY; COLON; CONFERENCE PAPER; CONTROLLED STUDY; GENE; GENE EXPRESSION; HIRSCHSPRUNG DISEASE; HISTOCHEMISTRY; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; PRIORITY JOURNAL; SULFATION;

EID: 0032996525     PISSN: 00223468     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-3468(99)90202-6     Document Type: Conference Paper

References (19)

1. Corfield A: The role of mucins in the gastrointestinal tract: An overview with emphasis on nutrition, in Renner B, Sawatzki G (eds): New prospectives in infant nutrition. Stuttgart, Georg Thieme Verlag, 1993, pp 57-63
2. Aslam A, Spicer RD, Corfield AP: Children with Hirschsprung disease have an abnormal mucus defensive barrier independent of bowel innervation status. J Pediatr Surg 32:1206-1210, 1997
3. Aslam A, Spicer RD, Corfield AP: Turnover of radioactive mucin precursors in Hirschsprung disease colon correlates with the development of enterocolitis. J Pediatr Surg 33:103-105, 1998
4. Akkary S, Sahwy E, Kandil W, et al: A histochemical study of the mucosubstances of the colon in cases of Hirschsprung's disease with and without enterocolitis. J Pediatr Surg 16:664-668, 1981
5. Allen A, Pearson JP: Mucus glycoproteins in the normal gastrointestinal tract. Eur J Gastroenterol Hepatol 5:193-199, 1993
6. Allen A, Bell A, Mantle M, et al: The structure and physiology of gastrointestinal mucins, in Chantier EN, Elders JB, Elstein M, (eds): Mucus in Health and Disease II, New York, NY, Plenum Press, 1982, p 144
7. Lamont JT: Mucus: The front line of intestinal mucosal defence. Neuroimmunology of gastrointestinal mucosa. Implications for inflammatory diseases. ANNYAS 664:190-201, 1992
8. Smith AC, Podolsky DK: Colonic mucin glycoproteins in health and disease. Clin Gastroenterol 15:815-837, 1986
9. Strous GJ, Dekker J: Mucin-type glycoproteins. Crit Rev Biochem Mol Biol 27:57-92, 1992
10. Pietriwski J, Slomiany A, Murty VLN, et al: Inhibition of Helicobacter pylori colonization by sulfated gastric mucin. Biochem Int 24:749-756, 1991
11. Jass IR, Roberton A: Colorectal mucin histochemistry in health and disease: A critical review. Pathol Int 44:487-504, 1994
12. Filipe MI: The histochemistry of intestinal mucins. Changes in disease, in Whitehead R (ed): Gastrointestinal and Oesophageal Pathology. Edinburgh, Scotland, Churchill Livingstone, 1989, pp 65-89
13. Corfield AP, Wagner SA, O'Donnell LJD, et al: The roles of enteric bacterial sialidase, sialate O-acetyl esterase, and glycosulfatase in the degradation of human colonic mucin. Glycoconj J 10:72-81, 1993
14. Corfield A, Wagner SA, Clamp JR, et al: Mucin degradation in the human colon: Production of sialidase, sialate-O-transferase, N-Acetylneuraminate lyase, arylesterase, and glycosulphatase activities by strains of faecal bacteria. Infec Immunol 60:3971-3978, 1992
15. Richman PI, Bodmer WF: Monoclonal antibodies to human colorectal epithelium: Markers for differentation and tumour characterization. Int J Cancer 39:317-328, 1987
16. Irimura T, Wynn DM, Hagar LG, et al: Human colonic sulfomucin identified by a specific monoclonal antibody. Cancer Res 51:5728-5735, 1991
17. Van Klinken BJW, Dekker J, Büller HA, et al: Biosynthesis of mucins (MUC2-6) along the longitudinal axis of the human gastrointestinal tract. Am J Physiol 273:G296-G302, 1997
18. Van Klinken BJW, Jan-Willem B, Dekker J, et al: Mucin gene structure and expression: Protection versus adhesion. Am J Phisiol 269:G613-G627, 1995
19. Filipe MI, Lake BD: Histochemistry in Pathology. Edinburgh, Scotland, Churchill Livingstone, 1983